甲基二氯硅烷-甲基乙烯基二氯硅烷二元体系等压汽液平衡

利用新型泵式沸点仪,在１０１．３ｋＰａ下测定了甲基二氯硅烷－甲基乙烯基二氯硅烷二元体系液相平衡数据,同时,对甲基乙烯基二氯硅烷的临界性质进行了估算。分别用Ｍａｒｇｕｌｅｓ,ＶａｎＬａａｒ,Ｗｉｌｓｏｎ和ＮＲＴＬ模型进行了关联,结果令人满意。     

Ag microparticles embedded in Si nanowire arrays: a novel catalyst for gas-phase oxidation of high alcohol to aldehyde

A novel catalyst of silver microparticles embedded in a silicon nanowire array support (Ag@SiNW) was prepared by an in situ electroless metal deposition method; it exhibited high selectivity and stability for gas-phase oxidation of high alcohol to its corresponding aldehyde.     

Temperature-insensitive 2-D tilt sensor by incorporating fiber Bragg gratings with a hybrid pendulum

A novel two-dimensional (2-D) tilt sensor is demonstrated by incorporating only two fiber Bragg gratings (FBGs) with a hybrid pendulum transducer. The pendulum transducer is specially designed with hollow half at the upper side and solid half at the lower side. Two FBGs were attached on the surface separated by one fourth of the circumference of the rod of pendulum and across the interface of its hollow and solid parts. Reflection peaks of FBGs split by the applied tilt angle. 2-D tilt angle can be determined by monitoring the wavelength separations of the split peak in two FBGs, which is inherently insensitive to temperature. In the experiment, a sensitivity of 0.054 nm/° over a wide range of 20º has been achieved, with the accuracy of 0.27°.     

Rapid determination of lignosulfonate depolymerization products by advanced polymer chromatography

Depolymerized lignin products are very complex mixtures. Based on a depolymerization solution of commercially available sodium lignosulfonate under mild conditions, a fast and efficient method for the separation and direct characterization of the degree and efficiency of the acid‐catalyzed depolymerization of lignin was developed in this study. Using an ultraviolet detector, the depolymerized lignosulfonate products were well separated and characterized according to the relative molar mass distribution on an advanced polymer chromatographic system with three ethylene‐bridged hybrid columns having small pore sizes (45 Å) in series and tetrahydrofuran as the mobile phase. The developed advanced polymer chromatography method enabled the detection of low‐molecular‐weight lignin degradation products (M_n = 260–1100 Da) with high peak resolutions in less than 7.2 min. Furthermore, preliminary advanced polymer chromatography studies to determine the influence of reaction temperature on the depolymerized products indicated that the depolymerized aromatics fell in several molecular weight ranges with an extremely low dispersity. This new approach can be used for the rapid analysis of lignin depolymerization products.     

致密多孔介质中气体渗流的格子Boltzmann模拟

为了能用格子Boltzmann方法来正确地刻画致密多孔介质中微尺度流动问题,对单通道模型进行推广,并将其应用于孔隙群里气体渗流的数值模拟.通过对部分具有代表性的多孔介质中的实际流动问题进行模拟,研究渗透率与平均压力和Knudsen数之间的相互关系.基于理论分析及相关文献中的试验结果,验证模拟结果,为用格子Boltzmann方法深入研究气体渗流问题奠定基础.     

Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity

The histone lysine methyltransferase EZH2 has been reported to play important roles in cancer aggressiveness, metastasis and poor prognosis. In this study, a series of benzomorpholine derivatives were synthesized and biologically evaluated as EZH2 inhibitors. The target compounds were obtained in good yields from 3-amino-5-bromo-2-hydroxybenzoic acid via cyclization, Suzuki coupling and amidation as the key steps. A preliminary optimization study led to the discovery of several potent novel EZH2 inhibitors (6b, 6c, 6x and 6y). Moreover, 6y inhibited the A549 and NCI-H1975 cell lines (IC₅₀?=?1.1 µM and 1.1 µM, respectively). Further studies indicated that 6y can reduce EZH2 expression in intact cells and cause cell arrest in the G2/M phase.

     

Ga2O3/HZSM-5催化剂在乙烷脱氢反应中的积碳行为和MgO的修饰作用

研究了Ga₂O₃/HZSM-5催化剂在乙烷脱氢反应中的积碳、再生以及MgO的修饰作用. 通过激光拉曼、TG-MS和NH₃-TPD等表征手段对反应过程的积碳种类和速率进行研究. 实验结果表明, 催化剂强酸中心上容易发生乙烷裂解生成甲烷的副反应并产生积碳, 其中石墨型积碳在反应过程中难以消除, 是导致催化剂失活的主要原因. MgO修饰可以减少催化剂强酸中心的量, 对乙烷裂解生成甲烷的副反应活性起到显著抑制作用, 并使积碳速率得到有效控制, 从而提高了催化剂的稳定性和乙烯的选择性. 催化剂再生时, 在空气气氛中加入水蒸气能够提高脱除石墨化碳的效率, 经420 ℃再生后催化剂的活性得到明显恢复.     

高校化学类专业开展新工科建设的建议

The education characters of emerging engineering education (3E) is summarized. The necessary for reform and construction of new chemistry-related majors based on the ideal of 3E is discussed. The main ideas and ways proposed and the main research progresses made by the Instructional Committee of Chemistry Majors, Mistry of Education are briefly introduced with emphasis on the setup of two new majors namely "Chemistry Metrology and Technology" and "Intelligent Molecular Engineering" and reform of "Energy Chemistry". It is of guidance significance for the future reform of chemistry-related majors based on the 3E idea.     

Temperature-insensitive FBG tilt sensor with a large measurement range

A novel two-dimensional tilt sensor with a large measurement range is demonstrated by using four fiber Bragg gratings (FBGs) attached on a cylindrical cantilever-based pendulum. Experimental results show that tilt accuracy of ±0.2° and resolution of 0.013° have been achieved in the range of −40°-40°. The temperature effect is automatically eliminated without additional temperature compensation elements.     

Surface effects on the persistence length of nanowires and nanotubes

Surface effects on the persistence length of quasi-one-dimensional nanomaterials are investigated by using the theory of surface elasticity and the core–shell model of nanobeams. A simple and unified expression is provided to determine the persistence length of nanowires and nanotubes with any regular polygonal cross-sections. It is demonstrated that surface effects have a distinct influence on the persistence length when the characteristic sizes of materials shrink to nanometers. This work is helpful not only for understanding the size-dependent behavior of nanomaterials but also for the design of devices based on nanotubes or nanowires.