Microdetermination of carbon in organic compounds by oxygen flask combustion with atomic absorption spectrophotometric,gravimetric, and titrimetric finishes

A simple and accurate method is presented for the determination of the carbon content of organic compounds by electric oxygen flask combustion. Five results are obtained for one experiment by atomic absorption spectrophotometric, gravimetric, and titrimetric finishes.     

Mutually unbiased projectors and duality between lines and bases in finite quantum systems

Quantum systems with variables in the ring Z(d)$\mathbb{Z}\left(d\right)$ are considered, and the concepts of weak mutually unbiased bases and mutually unbiased projectors are discussed. The lines through the origin in the Z(d)×Z(d)$\mathbb{Z}\left(d\right)\times \mathbb{Z}\left(d\right)$ phase space, are classified into maximal lines (sets of d$d$ points), and sublines (sets of d_i$d_i$ points where d_i|d$d_i|d$). The sublines are intersections of maximal lines. It is shown that there exists a duality between the properties of lines (resp., sublines), and the properties of weak mutually unbiased bases (resp., mutually unbiased projectors).     

Electronic structure of some adenosine receptor antagonists. III. Quantitative investigation of the electronic absorption spectra of alkyl xanthines

Quantitative and comparative investigation of the electronic absorption spectra of theophylline, caffeine and their derivatives is reported. The spectra of theophylline, caffeine and theobromine were compared to establish the predominant tautomeric species in solution. This comparison, analysis of solvent effects and assignments of the observed transitions via MO computations indicate the exits of only one tautomeric species in solution that is the N7 form. A low-lying triplet state was identified which corresponds to a HOMO-LUMO transition. This relatively long-lived T1 state is always less polar than the ground state and may very well underlie the photochemical reactivity of alkyl xanthines. Substituents of different electron donating or withdrawing strengths and solvent effects are investigated and analyzed. The present analysis is facilitated via computer deconvolution of the observed spectra and MO computation.     

Perisomalien A,a new cytotoxic scalarane sesterterpene from the fruits of Periploca somaliensis

Abstract

The CHCl₃ fraction of MeOH extract of Periploca somaliensis (family Asclepiadaceae) fruits afforded a new scalarane sesterterpene, namely perisomalien A (1), along with lupeol acetate (2), β-amyrin (3), cycloart-23Z-ene-3β,25-diol (4), and β-sitosterol-3-O-β-D-glucopyranoside (5). Their chemical structures were established by various spectroscopic analyses, in addition to comparison with the formerly reported data. Moreover, the cytotoxic activity of these metabolites was assessed towards MCF-7, HepG2, and HCT-116 tumour cell lines using sulforhodamine B (SRB) assay. Compound 4 showed the most potent cytotoxic profile with IC₅₀ 9.0?µM towards MCF-7, compared to doxorubicin (IC₅₀ 0.18?µM). Also, 1 and 4 possessed the most potent effect towards HepG2 with IC₅₀s 26.7 and 25.9?μM, respectively. In addition, all tested compounds showed cytotoxic effects with IC₅₀ values ranging from 19.9 to 39.3?µM against HCT-116.     

Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract

Foods with medical value have been proven to be beneficial, and they are extensively employed since they integrate two essential elements: food and medication. Accordingly, diabetic patients can benefit from papaya because the fruit is low in sugar and high in antioxidants. An RP-HPLC method was designed for studying the pharmacokinetics of metformin (MET) when concurrently administered with papaya extract. A mobile phase of 0.5 mM of KH₂PO₄ solution and methanol (65:35, v/v), pH = 5 ± 0.2 using aqueous phosphoric acid and NaOH, and guaifenesin (GUF) were used as an internal standard. To perform non-compartmental pharmacokinetic analysis, the Pharmacokinetic program (PK Solver) was used. The method’s greenness was analyzed using two tools: the Analytical GREEnness calculator and the RGB additive color model. Taking papaya with MET improved the rate of absorption substantially (time for reaching maximum concentration (T_max) significantly decreased by 75% while maximum plasma concentration (C_max) increased by 7.33%). The extent of absorption reduced by 22.90%. Furthermore, the amount of medication distributed increased (30.83 L for MET concurrently used with papaya extract versus 24.25 L for MET used alone) and the clearance rate rose by roughly 13.50%. The results of the greenness assessment indicated that the method is environmentally friendly. Taking papaya with MET changed the pharmacokinetics of the drug dramatically. Hence, this combination will be particularly effective in maintaining quick blood glucose control.     

Directed packings with block size 5 and even ν

Let andk be positive integers. A transitively orderedk-tuple (a ₁,a ₂,...,a _k) is defined to be the set {(a _i, a_j) 1i<jk} consisting ofk(k–1)/2 ordered pairs. A directed packing with parameters ,k and index =1, denoted byDP(k, 1; ), is a pair (X, A) whereX is a -set (of points) andA is a collection of transitively orderedk-tuples ofX (called blocks) such that every ordered pair of distinct points ofX occurs in at most one block ofA. The greatest number of blocks required in aDP(k, 1; ) is called packing number and denoted byDD(k, 1; ). It is shown in this paper that for all even integers , where [x] is the floor ofx.     

Computational study of decaying annular vortex flow using the Rε/k − ε turbulence model

In this article, we present three dimensional CFD study of turbulent vortex flow in an annular passage using OpenFOAM 1.6. The vortex flow is generated by introducing the flow through a tangential entry to the passage. For the analysis presented in this article, turbulence was modeled using the R_ε/k − ε model, in addition, a comparison between such model with the standard k − ε model was conducted and discussed. The main characteristics of the flow such as vortex structure and recirculation zone were investigated. It was found that flow is subjected to Rankine vortex structure with three forced vortex regimes and a free vortex region near to the outer wall. The phenomenon of vortex decay was investigated by depicting the swirl number trend along the axial direction of the flow domain. It was found that the vortex decay is subjected to an exponential decay behavior. New coefficients for the exponential decay correlation were derived based on local values of velocity components in different radial planes.     

Optimizing head/media electrical characterization in the presence of skew at high track density

The skew angle causes a discrepancy in determining the reader-to-writer offset (RWO) when using different periodical patterns in track profile tests. It also separates the peak overwrite (OW) from the peak high frequency amplitude HFA, (1 T periodical pattern) on corresponding track profiles. Furthermore, higher track density and larger skew angle exacerbate the skew effect and induce more RWO error, thus impacting the parametric performance optimization. Simulation studies are used to interpret the skew effect on the RWO determination and OW cross-track characteristics. Based on experimental investigations and simulation analyses, using the HFA, track profile for deriving the optimal RWO is proposed for spin-stand tests. Actual parametric characterization has proven that the optimal RWO minimized the skew effect and the RWO error, thus improving the parametric performance and reducing the test variation. The method is beneficial and necessary for the high track density characterization.     

The fractional coupled KdV equations： Exact solutions and white noise functional approach

Variable coefficients and Wick-type stochastic fractional coupled KdV equations are investigated. By using the mod- ified fractional sub-equation method, Hermite transform, and white noise theory the exact travelling wave solutions and white noise functional solutions are obtained, including the generalized exponential, hyperbolic, and trigonometric types.     

Large eddy simulations of partially premixed ethanol dilute spray flames using the flamelet generated manifold model

The paper presents Large Eddy Simulations (LESs) for the Sydney ethanol piloted turbulent dilute spray flames ETF2, ETF6, and ETF7. The Flamelet Generated Manifold (FGM) approach is employed to predict mixing and burning of the evaporating fuel droplets. A methodology to match the experimental inflow spray profiles is presented. The spray statistical time-averaged results show reasonable agreement with mean and RMS data. The Particle Size Distribution (PSD) shows a good match downstream of the nozzle exit and up to x/D = 10. At x/D = 20 and 30 the PSD is under-predicted for droplets with mean diameter D10 > 20μm and over-predicted for the smaller size droplets. The simulations reasonably predict the reported mean flame structure and length. The effect of increasing the carrier velocity (ETF2–ETF7) or decreasing the liquid fuel injection mass flow rate (ETF2–ETF6) is found to result in a leaner, shorter flame and stronger spray–flow interactions. Higher tendency to local extinction is observed for ETF7 which is closer to blow-off compared to ETF2 and has higher scalar dissipation rates, higher range of Stokes number, and faster droplet response. The possible sources of LES-FGM deviations from the measurements are discussed and highlighted. In particular, the spray time-averaged statistical error contribution is quantified and the impact of the inflow uncertainty is studied. Sensitivity analysis to the pre-vaporized nozzle fuel mass fraction show that such small inflow perturbations (by ±?2% for the ETF2 flame) have a strong impact on the flame structure, and the droplets’ dynamics. Conditional scatter plots show that the flame exhibits wide range of mixing conditions and bimodal mixing lines particularly at upstream locations (x/D?相似文献