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71.
F. M. Horn und R. Zaloziecki 《Fresenius' Journal of Analytical Chemistry》1890,29(1):718-720
Ohne Zusammenfassung 相似文献
72.
Anna Luise Grab Dirk Hose Patrick Horn Elisabetta Ada Cavalcanti-Adam Anja Seckinger Martin Müller 《Particle & Particle Systems Characterization》2021,38(3):2000263
In the malignant plasma cell disease multiple myeloma (MM), bone lesions and resulting fractures caused by MM cell (MMC) accumulation represent a major cause of morbidity and mortality. Despite recent advantages in systemic treatment, residual MMCs remain, especially in bone lesions. Therefore an interfacial delivery system for local treatment of MM and induced bone disease based on polyelectrolyte complex nanoparticles (PEC NP) loaded with bone morphogenetic protein 6 (BMP-6) inducing de-novo bone formation and MMC apoptosis is presented herein. BMP-6 loaded PEC NP are fabricated by defined mixing bio-related cationic and anionic polysaccharides and BMP-6 according to molar ratio of BMP-6/PEC-NP of 1/3. BMP-6/PEC NP bound to a model substrate releases 10% BMP-6 sustainably within two weeks as accessed by infrared spectroscopy. BMP-6 loaded PEC NP adheres to cell membranes of MMCs and MSCs and activated phosphorylation of Smad 1/5. Osteogenic differentiation (ALP-concentration) is enhanced in MSCs (p < 0.05). All patient samples (10/10) of MMCs show significant induction of apoptosis (median 84%, p < 0.05). Finally, BMP-6/PEC NP are successfully integrated in a commercial hyaluronic acid based hydrogel material revealing MMC death as principal proof for the local treatment of MM induced bone lesions. 相似文献
73.
J. Horn 《Mathematische Annalen》1897,49(3-4):453-472
Ohne Zusammenfassung 相似文献
74.
R. Weichenhain A. Horn E.W. Kreutz 《Applied Physics A: Materials Science & Processing》1999,69(7):S855-S858
Nano- and picosecond laser radiation offers better possibilities by achieving higher accuracy in microstructuring because of much lower heat load compared to larger pulses. The influence of wavelength, pulse energy, overlap and the properties of processing gas atmosphere on material removal and roughness of ceramics are investigated for ns-pulses. The removal threshold and the removal rate per pulse for ns- and ps- laser pulses are presented. Strategies, which reduce the surface roughness and enhance the efficieny of the production of three dimensional structures are reported. These results show the parameter field which permits a precise material removal during the production of microstructures without damaging the remaining structure. 相似文献
75.
76.
Navasardyan T Adams GS Ahmidouch A Angelescu T Arrington J Asaturyan R Baker OK Benmouna N Bertoncini C Blok HP Boeglin WU Bosted PE Breuer H Christy ME Connell SH Cui Y Dalton MM Danagoulian S Day D Dodario T Dunne JA Dutta D El Khayari N Ent R Fenker HC Frolov VV Gan L Gaskell D Hafidi K Hinton W Holt RJ Horn T Huber GM Hungerford E Jiang X Jones M Joo K Kalantarians N Kelly JJ Keppel CE Kubarovski V Li Y Liang Y Malace S Markowitz P McGrath E McKee P Meekins DG Mkrtchyan H Moziak B 《Physical review letters》2007,98(2):022001
A large data set of charged-pion (pi+/-) electroproduction from both hydrogen and deuterium targets has been obtained spanning the low-energy residual-mass region. These data conclusively show the onset of the quark-hadron duality phenomenon, as predicted for high-energy hadron electroproduction. We construct several ratios from these data to exhibit the relation of this phenomenon to the high-energy factorization ansatz of electron-quark scattering and subsequent quark-->pion production mechanisms. 相似文献
77.
In this paper we present inspection results from several bonded wafer systems using a newly developed infrared gray-field
polariscope (IR-GFP). This device measures the residual stress-fields associated with defects trapped at the bonded interface
to enable the detection of subwavelength defects. Results from IR-GFP imaging are contrasted with conventional infrared transmission
(IRT) imaging of the same samples, showing marked improvements in defect detection as well as the ability to quantify the
residual stress fields. This inspection method reveals that interfaces deemed defect-free using IRT imaging may be, in fact,
teeming with defects. 相似文献
78.
Many authors have recognized that traffic under the traditional car‐following model (CFM) is subject to flow instabilities. A recent model achieves stability using bilateral control (BCM)—by looking both forward and backward [1]. (Looking back may be difficult or distracting for human drivers, but is not a problem for sensors.) We analyze the underlying systems of differential equations by studying their eigenvalues and eigenvectors under various boundary conditions. Simulations further confirm that bilateral control can avoid instabilities and reduce the chance of collisions. 相似文献
79.
Ľ. Vrtoch M. Pipíška M. Horník J. Augustín J. Lesný 《Journal of Radioanalytical and Nuclear Chemistry》2011,287(3):853-862
In order to gain biosorbent that would have the ability to bind cesium ions from water solution effectively, potassium nickel
hexacyanoferrate(II) (KNiFC) was incorporated into the mushroom biomass of Agaricus bisporus. Cesium sorption by KNIFC-modified A. bisporus biosorbent was observed in batch system, using radiotracer technique using 137Cs radioisotope. Kinetic study showed that the cesium sorption was quite rapid and sorption equilibrium was attained within
1 h. Sorption kinetics of cesium was well described by pseudo-second order kinetics. Sorption equilibrium was the best described
by Freundlich isotherm and the distribution coefficient was at interval 7,662–159 cm3 g−1. Cesium sorption depended on initial pH of solution. Cesium sorption was very low at pH0 1.0–3.0. At initial pH 11.0, maximum sorption of cesium was found. Negative effect of monovalent (K+, Na+, NH4
+) and divalent (Ca2+, Mg2+) cations on cesium sorption was observed. Desorption experiments showed that 0.1 M potassium chloride is the most suitable
desorption agent but the complete desorption of cesium ions from KNiFC-modifed biosorbent was not achieved. 相似文献
80.
Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy 总被引:1,自引:0,他引:1
Sokolova V Ludwig AK Hornung S Rotan O Horn PA Epple M Giebel B 《Colloids and surfaces. B, Biointerfaces》2011,87(1):146-150
Exosomes from three different cell types (HEK 293T, ECFC, MSC) were characterised by scanning electron microscopy (SEM), dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA). The diameter was around 110 nm for the three cell types. The stability of exosomes was examined during storage at -20°C, 4°C, and 37°C. The size of the exosomes decreased at 4°C and 37°C, indicating a structural change or degradation. Multiple freezing to -20°C and thawing did not affect the exosome size. Multiple ultracentrifugation also did not change the exosome size. 相似文献