Vortex Counter-Current Chromatography: Performance of a New Preparative Column

A new preparative column for the vortex counter-current chromatograph was fabricated by making many (966) cylindrical separation units to a high-density polyethylene disk and then threading them with 6–40 taps. The resulting column had a total capacity of 364 mL. The performance of this vortex column was examined with three different two-phase solvent systems each using a set of suitable test samples: hexane–ethyl acetate–methanol–0.1 M hydrochloric acid (1:1:1:1, v/v) for the separation of DNP-amino acids; 1-butanol–acetic acid–water (4:1:5, v/v) for the separation of dipeptides; and hexane–acetonitrile–water (20:15:2, v/v) for the separation of Sudan dyes. Most of the separations show high partition efficiency of over a thousand theoretical plates, as expected based on the results previously obtained in preliminary separations with a small column. Overall, the results of the present study suggest that further improvement of the partition efficiency can be obtained by the modifying column configuration.

     

Biological evaluation of novel selenazole‐based compounds as potential thioredoxin reductase inhibitors

Recently, thioredoxin reductase as a target for treatment of tumors has attracted the attention of scientists. 1,2‐[Bis(1,2‐benzisoselenazolone‐3(2 H)‐ketone)]ethane (ethaselen, BBSKE, PCT: CN02/00412), designed and synthesized previously, is an effective thioredoxin reductase inhibitor; presently it is in phase II clinical trials, targeting gastric cancer, lung cancer and colon cancer. To seek more novel and effective anticancer drugs, we have developed many selenazole‐based compounds. Evaluation of the thioredoxin reductase inhibitory effect and investigation of the mechanism of anticancer drugs require abundant thioredoxin reductase, but since commercial thioredoxin reductase is expensive its use is often limited. Therefore, the preparation of thioredoxin reductase is necessary. Base on the above investigation, in this work we have prepared thioredoxin reductase and evaluated selenazole‐based compounds, and found that 44 compounds have high inhibitory effect on thioredoxin reductase with IC₅₀ < 10 µ m , of which 16 compounds have IC₅₀ values below 1 µ m . This is helpful in investigating and elucidating the mechanism of this kind of compound. Copyright © 2012 John Wiley & Sons, Ltd.     

a-CdSe超快光电探测器特性研究

本文报道淀积条件对非晶态硒化镉(a-CdSe)薄膜微区结构的影响,并对利用a-CdSe为光敏介质的超快光电探测器的特性进行了比较深入的测试研究。     

The Choquet-Deny convolution equation μ=μ*σ for probability measures on Abelian semigroups

In this note, we characterize the regular probability measures satisfying the Choquet-Deny convolution equation =* on Abelian topological semigroups for a given probability measure .     

Periodic Solution of a Nonautonomous Diffusive Food Chain System of Three Species with Time Delays

Abstract By using the continuation theorem of coincidence degree theory,the existence of a positive periodicsolution for a nonautonomous diffusive food chain system of three species. dx_1(t)/dt=x_1(t)[r_1(t)-a_(11)(t)x_1(t)-a_(12)(t)x_2(t)]+D_1(t)[y(t)-x_1(t)], dx_2(t)/dt=x_2(t)[-r_2(t)+a_(21)(t)x_1(t-r_1)-a_(22)(t)x_2(t)-a_(23)(t)x_3(t)], dx_3(t)/dt=x_3(t)[-r_3(t)+a_(32)(t)x_2(t-r_2)-a_(33)(t)x_3(t)], dy(t)/dt=y(t)[r_4(t)-a_(44)(t)y(t)]+D_2(t)[x_1(t)-y(t)]+D_2(t)[x_1(t)-y(t)],is established,where,r_i(t),a_(ii)(t)(i=1,2,3,4),D_i(t)(i=1,2),a_(12)(t),a_(21)(t),a_(23)(t)and a_(32)(t) are all positiveperiodic continuous functions with period w>0,T_i(i=1,2)are positive constants.     

全同超形变带转动惯量的粒子数守恒计算

利用推转壳模型的粒子数守恒方法计算了超形变(SD)转动带¹⁹²Hg和¹⁹⁴Hg(1,2,3)的带首转动惯量.分析了带首附近的组态结构及带首转动惯量随对力强度的变化.带首转动惯量之差δJ₀对对力强度十分敏感,而对Nilsson能级参数K、μ及形变参数并不敏感.对力及堵塞效应是造成带首转动惯量差别的主要因素.但与正常形变核相比,对力强度似有较大程度减弱.     

一类非线性椭圆问题的schwarz算法

其中考虑下述泛函最小问题:求u∈W01,α(Ω),使F(u)=     

具有功能反应的两斑块扩散时滞竞争系统正周期解的存在性

§ 1　ＩｎｔｒｏｄｕｃｔｉｏｎＦｏｒｍａｎｙｓｐｅｃｉｅｓｔｈｅｓｐａｔｉａｌｆａｃｔｏｒｓａｒｅｉｍｐｏｒｔａｎｔｉｎｐｏｐｕｌａｔｉｏｎｄｙｎａｍｉｃｓ .Ｔｈｅｔｈｅｏｒｅｔｉｃａｌｓｔｕｄｙｏｆｓｐａｔｉａｌｄｉｓｔｒｉｂｕｔｉｏｎｈａｓｂｅｅｎｅｘｔｅｎｓｉｖｅｌｙｓｔｕｄｉｅｄｉｎｍａｎｙｐａｐｅｒｓ .Ｍｏｓｔｏｆｔｈｅｐｒｅｖｉｏｕｓｐａｐｅｒｓｆｏｃｕｓｅｄｏｎｔｈｅｃｏｅｘｉｓｔｅｎｃｅｏｆｐｏｐｕｌａｔｉｏｎｓｍｏｄｅｌｌｅｄｂｙｓｔｓｔｅｍｓｏｆｏｒｄｉｎａｒｙｄｉｆｆｅｒｅ…     

ITERATIVE APPROXIMATION OF FIXED POINTS OF NON-LIPSCHITZIAN ASYMPTOTICALLY PSEUDOCONTRACTIVE MAPPINGS

The purpose of this paper is to investigate the problem of approximating fixed points of non-Lipschitizian asymptotically pseudocontractive mappings in an arbitrary real Banach space by the modified Ishikawa iterative sequences with errors.     

On complete integrability of a hierarchy of finite-dimensional Hamiltonian systems

A hierarchy of Hamiltonian systems obtained from the Lax pair of KdV hierarchy under the constraint condition on potentialu = q, q is presented. The independent integrals for these Hamiltonian systems are constructed by using recursion operator and shown to be in involution. Thus this hierarchy of Hamiltonian systems is completely integrable in the sense of Liouville, and they commute with each other.This project is supported by the National Natural Science Foundation of China.