Molybdenum hexacarbonyl supported on functionalized multi-wall carbon nanotubes: Efficient and highly reusable catalysts for epoxidation of alkenes with tert-butyl hydroperoxide

In the present work, highly efficient epoxidation of alkenes catalyzed by Mo(CO)₆ supported on amines modified multi-wall carbon nanotubes, MWCNTs, is reported. The prepared catalysts were characterized by elemental analysis, scanning electron microscopy, FT-IR and diffuse reflectance UV-Vis spectroscopic methods. These new heterogenized catalysts, [Mo(CO)₆@amines-MWCNT], were used as highly efficient catalysts for epoxidation of alkenes with tert-BuOOH. These robust catalysts could be reused several times without loss of their catalytic activities.     

Optimal solutions of a (3 + 1)-dimensional B-Kadomtsev-Petviashvii equation

We explored and specialized new Lie infinitesimals for the (3 + 1)-dimensional B-Kadomtsev-Petviashvii (BKP) using the commutation product, which results a system of nonlinear ODEs manually solved. Through two stages of Lie symmetry reduction, (3 + 1)-dimensional BKP equation is reduced to nonsolvable nonlinear ODEs using various combinations of optimal Lie vectors. Using the integration and Riccati equation methods, we investigate new analytical solutions for these ODEs. Back substituting to the original variables generates new solutions for BKP. Some selected solutions illustrated through three-dimensional plots.     

Stability analysis of fractional order neutral-type systems considering time varying delays,nonlinear perturbations,and input saturation

This article investigates the robust stability of fractional order neutral-type systems involving nonlinear perturbations and time varying delays in the presence of input saturation. Design criteria, expressed in terms of linear matrix inequalities, are derived with the aid of the Lyapunov Krasovskii functional for the state feedback controller. Based on the cone complementarity linearization method, an optimization problem is also formulated for finding the controller gains subject to maximizing the domain of attraction. The main results are confirmed by numerical simulations.     

Preparation,Characterization and Optimization of Egg Albumin Nanoparticles as Low Molecular‐Weight Drug Delivery Vehicle

Protein nanoparticles have been recognized as carriers to deliver low molecular‐weight drugs, anticancer drug, DNA, vaccines, oligonucleotides, peptides and etc. The purpose of this research was preparation of Egg Albumin (EA) nanoparticle with suitable size/size distribution and good surface properties for drug delivery application based on simple coacervation method along with optimization of the nanoparticles by employing Taguchi method. Several synthesis parameters were examined to characterize their impacts on nanoparticle size and topography. These variables were including temperature, EA concentration, desolvating agent volume, pH value and agitation speed. In addition, size and morphology of prepared nanoparticles were analyzed by photon correlation spectroscopy (PCS) as well as atomic force microscopy (AFM). As result of Taguchi analysis in this research, desolvating agent volume and pH were most influencing factors on particle size. The minimum size of nanoparticles (～51 nm) were obtained at Temperature 55 °C, 30 mg/ml EA concentration, desolvating agent volume 50 ml, agitation speed of 500 rpm and pH 4. The mechanistic of optimum conditions for preparing protein nanoparticles from Egg Albumin for the first time and their characterization as delivering nano system are discussed.     

Preparation and evaluation of a new 99mTc labeled bombesin derivative for tumor imaging

A variety of human tumors like prostate and breast cancer express bombesin receptors. Due to this a new bombesin analogue was labeled with ^99mTc via HYNIC and tricine as a coligand and investigated further. Peptide was synthesized on a solid phase using Fmoc strategy. Labeling with ^99mTc was performed at 100 °C for 10 min and radiochemical analysis involved ITLC and HPLC methods. The stability of radiopeptide was checked in the presence of human serum at 37 °C up to 24 h. Internalization was studied with the human GRP receptor cell line PC-3. The biodistribution was studied in mice. Labeling yield of >98% was obtained corresponding to a specific activity of ~80.9 GBq/μmol. Radiopeptide internalization into PC-3 cells was moderate and specific (10.7 ± 1.2% at 4 h). A high and specific GRP receptor expressing mouse tumor and pancreas uptake (1.12 ± 0.08 and 1.04 ± 0.11% ID/g after 1 h respectively) was also determined.     

Synthesis and characterization of activated carbon@zerovalent iron–nickel nanoadsorbent for highly efficient removal of Reactive Orange 16 from aqueous sample: experimental design,kinetic, isotherm and thermodynamic studies

Research on Chemical Intermediates - A simple and fast method based on activated carbon@nanozerovalent iron–nickel (AC@nZVI/Ni) nanoadsorbent was developed for highly efficient removal of...     

Allocation of advertising budget between multiple channels to support sales in multiple markets

We consider the allocation of a limited marketing budget between multiple channels in order to promote sales at multiple markets. The channels differ in their type, level of targetability (or reach), and costliness. We incorporate the “threshold effect” from each market in our resource allocation which requires some positive advertising investment in each market before much sales impact can be observed from it. The increased number of channels in recent years with the advent of digital advertising, along with the added complexity created by the threshold effect, necessitates the development of new allocation approaches. In this paper, we formulate the firm’s resource allocation decision as a nonlinear and nonseparable knapsack problem. We develop a branch and cut solution method which is enhanced by a heuristic approach. A set of numerical experiments illustrate the performance of our methods and evaluate the usefulness of two rule-of-thumb strategies commonly used in practice.