Tetracyclines Communication 33. Synthesis of 8-chloro-5-methoxy-3,10-dioxo-1,2,3,4,4a,9,9a,10-octahydroanthracene [5-chloro-1,3,4,4a,9a,10-hexahydro-8-methoxy-2,9-anthracenedione]

Summary 8-Chloro-5-methoxy-3,10-dioxo-1,2,3,4,4a,9,9a,10-octahydroanthracene (Ib) was synthesized; this can serve as an intermediary in the preparation of the tetracyclic analog (IIb) of aureomycin,Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 806–810, May, 1965 Original article submitted April 22, 1963For preceding communication see [1],The authors thank L. B. Senyavina for infrared spectrum measurements.     

The alkaloids from the fruits of the plant Daphniphyllaceae

Six alkaloids have been isolated from the fruits of the plant Daphniphyllaceae. Two of them are new alkaloids, namely methyl homodaphniphyllate (1) and daphnilactone-B (2). The structure of the former was deduced by chemical transformation from daphniphylline (3). The structure of daphnilactone-B was estimated by the exhaustive spectral analysis as well as by chemical evidences, and finally determined by an X-ray crystallographic analysis of the free base.