Global L p estimates for degenerate Ornstein–Uhlenbeck operators

We consider a class of degenerate Ornstein–Uhlenbeck operators in ${\mathbb{R}^{N}}We consider a class of degenerate Ornstein–Uhlenbeck operators in \mathbbR^N{\mathbb{R}^{N}} , of the kind

A o ?i, j=1p0aij?xixj2 + ?i, j=1Nbijxi?xj\mathcal{A}\equiv\sum_{i, j=1}^{p_{0}}a_{ij}\partial_{x_{i}x_{j}}^{2} + \sum_{i, j=1}^{N}b_{ij}x_{i}\partial_{x_{j}}      952. Risk Processes with Non-stationary Hawkes Claims Arrivals      Gabriele Stabile  Giovanni Luca Torrisi 《Methodology and Computing in Applied Probability》2010,12(3):415-429 We consider risk processes with non-stationary Hawkes claims arrivals, and we study the asymptotic behavior of infinite and finite horizon ruin probabilities under light-tailed conditions on the claims. Moreover, we provide asymptotically efficient simulation laws for ruin probabilities and we give numerical illustrations of the theoretical results.      953. Quantitative isoperimetric inequalities for a class of nonconvex sets      Giovanni Colombo  Khai T. Nguyen 《Calculus of Variations and Partial Differential Equations》2010,37(1-2):141-166 Quantitative versions (i.e., taking into account a suitable “distance” of a set from being a sphere) of the isoperimetric inequality are obtained, in the spirit of Fuglede (Trans Am Math Soc 314:619–638, 1989) and Fusco et al. (Ann Math 168:941–980, 2008) for a class of not necessarily convex sets called φ-convex sets. Our work is based on geometrical results on φ-convex sets, obtained using methods of both nonsmooth analysis and geometric measure theory.      954. Step by step palladium mediated syntheses of new 2-(pyridin-2-yl)-6-R-nicotinic acids and esters      Giacomo Luigi Petretto  Sergio Stoccoro  Maria Agostina Cinellu  Giovanni Minghetti 《Journal of organometallic chemistry》2010,695(2):256-259 Taking advantage of palladium peculiar “rollover” C,N cyclometallation, it is possible to promote C(3) functionalization of 6-alkyl-substituted-2,2′-bipyridines. The carbonylation reaction of rollover species [Pd(Ln)Cl]2, (HL1 = 6-isopropyl-2,2′-bipy, 1; HL2 = 6-neopentyl-2,2′-bipy, 2; HL3 = 6-ethyl-2,2′-bipy, 3; HL4 = 6-methyl-2,2′-bipy, 4) allowed the synthesis of 2-(pyridin-2-yl)-6-alkyl-nicotinic acids or esters. These nicotinic derivatives are extremely rare and, as far as we know, quite unreported in the case of the 6-substituted molecules.      955. Unusual photochemical dynamics of a bridged azobenzene derivative      Carstensen O  Sielk J  Schönborn JB  Granucci G  Hartke B 《The Journal of chemical physics》2010,133(12):124305 In a large-scale simulation study of ultrafast photochemical dynamics for an azobenzene compound with an additional ethylenic bridge we have found unexpected features: while the dynamics starting from the Z isomer follow a barrierless path with steep gradients, the dynamics starting from the E isomer proceed through a different conical intersection surrounded by a rather flat potential energy landscape and then encounter a sizeable barrier in the electronic ground state that markedly influences the reaction behavior. Direct comparisons with experimental static UV spectra, quantum yields, and transient absorption spectra show good agreement and reveal signatures of this unusual behavior.      956. Including quantum decoherence in surface hopping      Granucci G  Persico M  Zoccante A 《The Journal of chemical physics》2010,133(13):134111 In this paper we set up a method called overlap decoherence correction (ODC) to take into account the quantum decoherence effect in a surface hopping framework. While keeping the standard surface hopping approach based on independent trajectories, our method allows to account for quantum decoherence by evaluating the overlap between frozen Gaussian wavepackets, the time evolution of which is obtained in an approximate way. The ODC scheme mainly depends on the parameter σ, which is the Gaussian width of the wavepackets. The performance of the ODC method is tested versus full quantum calculations on three model systems, and by comparison with full multiple spawning (FMS) results for the S(1)→S(0) decay in the azobenzene molecule.      957. Synthesis of 2,3-dihydro-1,4-dithiinyl nucleosides via Pummerer-type glycosidation      Concetta Paolella  Flavio Cermola  Giovanni Palumbo 《Tetrahedron letters》2010,51(46):6060-6063 A straightforward procedure for the preparation of nucleoside analogue 1 and its regioisomer 2 containing a dihydro-1,4-dithiin as sugar moiety has been accomplished in four steps by our readily available heterocyclic system 5. Nucleobase insertion was carried out by direct addition of N4-acetylcytosine to sulfoxide derivatives via Pummerer-type glycosidation reaction.      958. Antihepatotoxic and antioxidant activities of methanol extract and isolated compounds from Ficus chlamydocarpa      Donfack JH  Simo CC  Ngameni B  Tchana AN  Kerr PG  Finzi PV  Vidari G  Giardina S  Buonocore D  Ngadjui BT  Moundipa PF  Marzatico F 《Natural product communications》2010,5(10):1607-1612 Free radicals, in particular radical oxygen species (ROS), play an important role in the aetiology and pathogenesis of various diseases. Current research in many countries focuses on the use of local medicinal plants as a promising source of liver protective agents. This paper describes the hepatoprotective effects of the methanol extract and four isolated compounds from Ficus chlamydocarpa on CCl4-induced liver damage, as well as the possible antioxidant mechanisms involved in this protection. The DPPH test, along with the beta-Carotene-Linoleic Acid Model System and Ferric-Reducing Antioxidant Power assays, as well as the inhibition of microsomal lipid peroxidation were used to measure radical-scavenging and antioxidant activities. Pretreatment of rats with the methanol extract of F. chlamydocarpa before CCl4 administration, significantly prevented serum increase of hepatic enzyme markers, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT), in a dose-dependent manner. The hepatoprotection was also associated with a significant enhancement in hepatic reduced glutathione (GSH) and a marked decrease of liver malondialdehyde (MDA). Among the four compounds 1-4, isolated from the methanol extract, alpha-amyrin acetate (1) and luteolin (4) showed a significant hepatoprotective activity, as indicated by their ability to prevent liver cell death and lactate dehydrogenase (LDH) leakage during CCl4 intoxication.      959. The Meyer-Schuster rearrangement: a new synthetic strategy leading to prostaglandins and their drug analogs, Bimatoprost and Latanoprost      Giuseppe Zanoni  Alessandro D’Alfonso  Lazzaro Feliciani  Giovanni Vidari 《Tetrahedron》2010,66(38):7472-8542 Gold(I) mediated Meyer-Schuster rearrangement for the installation of the ‘lower’ side chain of prostaglandins and their analogs has been developed. This Au-mediated rearrangement, featuring a low catalyst loading and mild reaction conditions, has been demonstrated to be an efficient alternative to the standard Horner-Wadsworth-Emmons reaction in prostaglandin chemistry. Moreover, the present results provide a new synthetic process leading to pharmacologically active prostanoids: Latanoprost and Bimatoprost, that continue to hold key positions in the anti-glaucoma drug market.      960. Gold-catalyzed regiospecific intermolecular hydrothiolation of allenes      Menggenbateer  Giovanni Ferrara  Tienan Jin  Yoshinori Yamamoto 《Tetrahedron letters》2010,51(35):4627-1712 AuBr3-catalyzed regiospecific intermolecular hydrothiolation of aromatic allenes and aromatic thiols afforded the corresponding dithioacetals in good yields at 0 °C in 5 min.      [首页] « 上一页 [91] [92] [93] [94] [95] 96 [97] [98] [99] [100] 下一页 » 末  页»

Risk Processes with Non-stationary Hawkes Claims Arrivals

We consider risk processes with non-stationary Hawkes claims arrivals, and we study the asymptotic behavior of infinite and finite horizon ruin probabilities under light-tailed conditions on the claims. Moreover, we provide asymptotically efficient simulation laws for ruin probabilities and we give numerical illustrations of the theoretical results.     

Quantitative isoperimetric inequalities for a class of nonconvex sets

Quantitative versions (i.e., taking into account a suitable “distance” of a set from being a sphere) of the isoperimetric inequality are obtained, in the spirit of Fuglede (Trans Am Math Soc 314:619–638, 1989) and Fusco et al. (Ann Math 168:941–980, 2008) for a class of not necessarily convex sets called φ-convex sets. Our work is based on geometrical results on φ-convex sets, obtained using methods of both nonsmooth analysis and geometric measure theory.     

Step by step palladium mediated syntheses of new 2-(pyridin-2-yl)-6-R-nicotinic acids and esters

Taking advantage of palladium peculiar “rollover” C,N cyclometallation, it is possible to promote C(3) functionalization of 6-alkyl-substituted-2,2′-bipyridines. The carbonylation reaction of rollover species [Pd(Lⁿ)Cl]₂, (HL¹ = 6-isopropyl-2,2′-bipy, 1; HL² = 6-neopentyl-2,2′-bipy, 2; HL³ = 6-ethyl-2,2′-bipy, 3; HL⁴ = 6-methyl-2,2′-bipy, 4) allowed the synthesis of 2-(pyridin-2-yl)-6-alkyl-nicotinic acids or esters. These nicotinic derivatives are extremely rare and, as far as we know, quite unreported in the case of the 6-substituted molecules.     

Unusual photochemical dynamics of a bridged azobenzene derivative

In a large-scale simulation study of ultrafast photochemical dynamics for an azobenzene compound with an additional ethylenic bridge we have found unexpected features: while the dynamics starting from the Z isomer follow a barrierless path with steep gradients, the dynamics starting from the E isomer proceed through a different conical intersection surrounded by a rather flat potential energy landscape and then encounter a sizeable barrier in the electronic ground state that markedly influences the reaction behavior. Direct comparisons with experimental static UV spectra, quantum yields, and transient absorption spectra show good agreement and reveal signatures of this unusual behavior.     

Including quantum decoherence in surface hopping

In this paper we set up a method called overlap decoherence correction (ODC) to take into account the quantum decoherence effect in a surface hopping framework. While keeping the standard surface hopping approach based on independent trajectories, our method allows to account for quantum decoherence by evaluating the overlap between frozen Gaussian wavepackets, the time evolution of which is obtained in an approximate way. The ODC scheme mainly depends on the parameter σ, which is the Gaussian width of the wavepackets. The performance of the ODC method is tested versus full quantum calculations on three model systems, and by comparison with full multiple spawning (FMS) results for the S(1)→S(0) decay in the azobenzene molecule.     

Synthesis of 2,3-dihydro-1,4-dithiinyl nucleosides via Pummerer-type glycosidation

A straightforward procedure for the preparation of nucleoside analogue 1 and its regioisomer 2 containing a dihydro-1,4-dithiin as sugar moiety has been accomplished in four steps by our readily available heterocyclic system 5. Nucleobase insertion was carried out by direct addition of N⁴-acetylcytosine to sulfoxide derivatives via Pummerer-type glycosidation reaction.     

Antihepatotoxic and antioxidant activities of methanol extract and isolated compounds from Ficus chlamydocarpa

Free radicals, in particular radical oxygen species (ROS), play an important role in the aetiology and pathogenesis of various diseases. Current research in many countries focuses on the use of local medicinal plants as a promising source of liver protective agents. This paper describes the hepatoprotective effects of the methanol extract and four isolated compounds from Ficus chlamydocarpa on CCl4-induced liver damage, as well as the possible antioxidant mechanisms involved in this protection. The DPPH test, along with the beta-Carotene-Linoleic Acid Model System and Ferric-Reducing Antioxidant Power assays, as well as the inhibition of microsomal lipid peroxidation were used to measure radical-scavenging and antioxidant activities. Pretreatment of rats with the methanol extract of F. chlamydocarpa before CCl4 administration, significantly prevented serum increase of hepatic enzyme markers, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT), in a dose-dependent manner. The hepatoprotection was also associated with a significant enhancement in hepatic reduced glutathione (GSH) and a marked decrease of liver malondialdehyde (MDA). Among the four compounds 1-4, isolated from the methanol extract, alpha-amyrin acetate (1) and luteolin (4) showed a significant hepatoprotective activity, as indicated by their ability to prevent liver cell death and lactate dehydrogenase (LDH) leakage during CCl4 intoxication.     

The Meyer-Schuster rearrangement: a new synthetic strategy leading to prostaglandins and their drug analogs, Bimatoprost and Latanoprost

Gold(I) mediated Meyer-Schuster rearrangement for the installation of the ‘lower’ side chain of prostaglandins and their analogs has been developed. This Au-mediated rearrangement, featuring a low catalyst loading and mild reaction conditions, has been demonstrated to be an efficient alternative to the standard Horner-Wadsworth-Emmons reaction in prostaglandin chemistry. Moreover, the present results provide a new synthetic process leading to pharmacologically active prostanoids: Latanoprost and Bimatoprost, that continue to hold key positions in the anti-glaucoma drug market.     

Gold-catalyzed regiospecific intermolecular hydrothiolation of allenes

AuBr₃-catalyzed regiospecific intermolecular hydrothiolation of aromatic allenes and aromatic thiols afforded the corresponding dithioacetals in good yields at 0 °C in 5 min.