Recent trends in the chemistry of Sandmeyer reaction: a review

Metal-catalyzed reactions play a vital part to construct a variety of pharmaceutically important scaffolds from past few decades. To carry out these reactions under mild conditions with low-cost easily available precursors, various new methodologies have been reported day by day. Sandmeyer reaction is one of these, first discovered by Sandmeyer in 1884. It is a well-known reaction mainly used for the conversion of an aryl amine to an aryl halide in the presence of Cu(I) halide via formation of diazonium salt intermediate. This reaction can be processed with or without copper catalysts for the formation of C–X (X?=?Cl, Br, I, etc.), C-CF₃/CF₂, C–CN, C–S, etc., linkages. As a result, corresponding aryl halides, trifluoromethylated compounds, aryl nitriles and aryl thioethers can be obtained which are effectively used for the construction of biologically active compounds. This review article discloses various literature reports about Sandmeyer-related transformations developed during 2000–2021 which give different ideas to synthetic chemists about further development of new and efficient protocols for Sandmeyer reaction.

Graphical abstract

An updated compilation of new approaches for Sandmeyer reaction is described in this review to construct a variety of carbon-halogen, carbon-phosphorous, carbon-sulfur, carbon-boron etc. linkages.

     

Magnetic and optical properties of Gd-Tl substituted M-type barium hexaferrites synthesized by co-precipitation technique

The substitution of numerous cations into hexagonal ferrite has been extensively used to endow novel properties and functionalities for various applications. In the present work Gd-Tl substituted barium hexaferrites prepared by co-precipitation process, having the composition Ba_0.75Cu_0.25(Gd_xTl_0.5-x)Fe_11.5O₁₉ (x = 0.0, 0.25 and 0.50). The hexaferrite formation during calcination of sample x = 0.25 was confirmed by TGA/DSC which was processed at 1000 °C for 3 h. The analysis of X-ray diffraction depicts the existence of magneto-plumbite structure with the formation of a minor secondary α–Fe₂O₃ phase x ≤ 0.0 and BaFe₂O₄ phase x ≤ 0.50. UV–Vis spectra reveal the dropping down behavior in the optical energy band gap from 2.47 eV to 1.74 eV. The grains with hexagonal platelet-like shape having size of 0.415–0.446 μm of magnetic powder nanoparticles (MPs) are observed by SEM images. The energy dispersive spectrometer (EDS) analysis was employed for presence of ferrite elements within a single particle. Hysteresis loops signifies the magnetization (M_s) and remnant magnetization (M_r) first increases up to x = 0.25 then reduces with the substitution (x) increment; contrarily, the coercivity (H_c) exhibited initially decreased with maximum content of Tl at x = 0.0 then increases at x = 0.25 after that it decreases at x = 0.50. Maximum values such as M_s (51.727 emu/g), M_r (28.061 emu/g), and H_c (4.057 kOe) are attained for x = 0.25 at room temperature. The synthesized magnetic nanoparticles are found to be suitable for microwave absorbing materials, permanent magnets, catalyst, high density recording media and optoelectronic devices.     

Open problems in some competition models

We present open problems and conjectures for some two-dimensional competition models, namely the logistic competition model and a Ricker-type competition model.     

Weak deflection angle and shadow cast by the charged-Kiselev black hole with cloud of strings in plasma

In this study, the gravitational deflection angle of photons in the weak field limit (or the weak deflection angle) and shadow cast by the electrically charged and spherically symmetric static Kiselev black hole (BH) in the string cloud background are investigated. The influences of the BH charge Q, quintessence parameter γ, and string cloud parameter a on the weak deflection angle are studied using the Gauss-Bonnet theorem, in addition to studying the influences on the radius of photon spheres and size of the BH shadow in the spacetime geometry of the charged-Kiselev BH in string clouds. Moreover, we study the effects of plasma (uniform and non-uniform) on the weak deflection angle and shadow cast by the charged-Kiselev BH surrounded by the clouds of strings. In the presence of a uniform/nonuniform plasma medium, an increase in the string cloud parameter a increases the deflection angle α. In contrast, a decrease in the BH charge Q decreases the deflection angle. Further, we observe that an increase in the BH charge Q causes a decrease in the size of the shadow of the BH. We notice that, with an increase in the values of the parameters γ and a, the size of the BH shadow increases, and therefore, the intensity of the gravitational field around the charged-Kiselev BH in string clouds increases. Thus, the gravitational field of the charged-Kiselev BH in the string cloud background is stronger than the field produced by the pure Reissner-Nordstrom BH. Moreover, we use the data released by the Event Horizon Telescope (EHT) collaboration, for the supermassive BHs M87* and Sgr A*, to obtain constraints on the values of the parameters γ and a.     

The \bar \partial -problem on q-pseudoconvex domains with applications

For a q-pseudoconvex domain Ω in ? ⁿ , 1 ≤ q ≤ n, with Lipschitz boundary, we solve the $\bar \partial $ -problem with exact support in Ω. Moreover, we solve the $\bar \partial $ -problem with solutions smooth up to the boundary over Ω provided that it has smooth boundary. Applications are given to the solvability of the tangential Cauchy-Riemann equations on the boundary.     

Mixed micellization and interfacial properties of dodecyltrimethylammonium bromide and tetraethyleneglycol mono-n-dodecyl ether in absence and presence of sodium propionate

Mixed micelle formation and interfacial properties of aqueous binary surfactant combinations of dodecyltrimethylammonium bromide (C12TAB) and tetraethyleneglycol mono-n-dodecyl ether (C12E4) at 30 degrees C in absence and presence of sodium propionate (NaPr) have been investigated. The critical micelle concentration, aggregation number, micropolarity and interfacial adsorption have been quantitatively estimated by surface tension and steady-state fluorescence measurements. The micellar and adsorption characteristics like composition, activity coefficients and mutual interaction parameters have been estimated following different theoretical treatments like that of Clint, Rubingh, Rodenas, Maeda, Blankschtein and Rosen. The analysis reveals very small mole fraction of cationic surfactant in both the mixed micelles and mixed monolayer inspite of synergism. Blankschtein's model predicts a continuous decrease in synergism due to the salt effect of NaPr; Rubingh's approach, on the contrary, indicates an increase in it above 30 mM of NaPr concentration. Aggregation number variation with NaPr indicates the same. Mixed monolayer shows better synergism compared to that in mixed micelles which increases with the addition of sodium propionate above 30 mM concentration.