Nephroprotective Effects of Alhagi camelorum against Cisplatin-Induced Nephrotoxicity in Albino Wistar Rats

Alhagi camelorum (AC) is an old plant with a significant therapeutic value throughout Africa, Asia, and Latin America. The overuse of cisplatin (Cis > 50 mg/m²) is associated with observed nephrotoxicity, ototoxicity, gastrotoxicity, myelosuppression, and allergic reactions. Remedial measures are needed for the protection of nephrotoxicity against cisplatin. Thus, we investigated the nephroprotective effects of AC plant extract to prevent cisplatin-induced nephrotoxicity in albino Wistar rats. The presence of polyphenols, phenolic compounds, tannins, and saponins was revealed during phytochemical investigation, and a significantly intense antioxidant activity was recorded. There were no toxicological symptoms in the treated rats, and no anatomical, physiological, or histological abnormalities were found compared to the control rats. The results of correcting cisplatin-induced nephrotoxicity revealed that the extract has a significant ability to treat kidney damage, with most parameters returning to normal after only three weeks of therapy. It is concluded that co-administration of cisplatin with AC extract showed exceptional nephroprotective effects at a dose of 600 mg/kg for Cis-induced nephrotoxicity.     

Quantum Computational Investigation of (E)-1-(4-methoxyphenyl)-5-methyl-N′-(3-phenoxybenzylidene)-1H-1,2,3-triazole-4-carbohydrazide

The title compound was synthesized and structurally characterized. Theoretical IR, NMR (with the GIAO technique), UV, and nonlinear optical properties (NLO) in four different solvents were calculated for the compound. The calculated HOMO–LUMO energies using time-dependent (TD) DFT revealed that charge transfer occurs within the molecule, and probable transitions in the four solvents were identified. The in silico absorption, distribution, metabolism, and excretion (ADME) analysis was performed in order to determine some physicochemical, lipophilicity, water solubility, pharmacokinetics, drug-likeness, and medicinal properties of the molecule. Finally, molecular docking calculation was performed, and the results were evaluated in detail.     

Determination of radiological hazard parameters and radioactivity concentrations in bauxite samples: the case of the Sutlegen Mine Region (Antalya,Turkey)

Journal of Radioanalytical and Nuclear Chemistry - Iron phosphate glasses with melting temperatures of?~?1300 °C were developed to immobilize spent nuclear fuels. The...     

Reduction electrochimique des oxydes de fer: Confrontation des caracteristiques electrochimiques et crist allographiques

Electrochemical properties of iron oxides, crystallographic data and examination of etching pits by scanning electron microscopy, suggest that ferric iron has electrochemical reactivity which differs according to its crystallographic position in the solid.     

Self-similar evolution of parabolic pulses in a laser

Self-similar propagation of ultrashort, parabolic pulses in a laser resonator is observed theoretically and experimentally. This constitutes a new type of pulse shaping in mode-locked lasers: in contrast to the well-known static (solitonlike) and breathing (dispersion-managed soliton) pulse evolutions, asymptotic solutions to the nonlinear wave equation that governs pulse propagation in most of the laser cavity are observed. Stable self-similar pulses exist with energies much greater than can be tolerated in solitonlike pulse shaping, and this has implications for practical lasers.     

All-optical transistor action with bistable switching in a photonic crystal cross-waveguide geometry

We demonstrate all-optical switching action in a nonlinear photonic crystal cross-waveguide geometry with instantaneous Kerr nonlinearity, in which the transmission of a signal can be reversibly switched on and off by a control input. Our geometry accomplishes both spatial and spectral separation between the signal and the control in the nonlinear regime. The device occupies a small footprint of a few micrometers squared and requires only a few milliwatts of power at a 10-Gbit/s switching rate by use of Kerr nonlinearity in AlGaAs below half the electronic bandgap. We also show that the switching dynamics, as revealed by both coupled-mode theory and finite-difference time domain simulations, exhibits collective behavior that can be exploited to generate high-contrast logic levels and all-optical memory.     

Generation of 2-nJ pulses from a femtosecond ytterbium fiber laser

We report a mode-locked ytterbium fiber laser that generates femtosecond pulses with energies as large as 2.2 nJ. This represents a 20-fold improvement in pulse energy compared with that of previously reported femtosecond Yb fiber lasers. The laser produces pulses as short as 52 fs, which are to our knowledge the shortest pulses to date from a Yb fiber laser. The laser is diode pumped by a wavelength-division multiplexing coupler, which leads to excellent stability.     

Role of copper species in the oxidative dimerization of arylboronic acids: synthesis of symmetrical biaryls

Certain Cu(I) and Cu(II) salts are able to mediate the dimerization of arylboronic acids in DMF. They provide the corresponding symmetrical biaryls in moderate to very good yields. It is possible to run the reaction catalytically under an oxygen atmosphere without a significant loss of yields.     

Electrophoretic deposition of bacterial cells

The possibility to use alternating current electrophoretic deposition (AC-EPD) to deposit living cells in the form of Staphylococcus aureus and Escherichia coli on stainless steel was assessed. The experimental results revealed that these bacteria can be successfully deposited on metallic surfaces from demineralized water and sucrose based solutions using asymmetric unbalanced electric fields. Cell viability of the deposited bacteria was influenced by the strain and deposition medium.