全文获取类型
收费全文 | 451篇 |
免费 | 24篇 |
国内免费 | 5篇 |
专业分类
化学 | 358篇 |
力学 | 14篇 |
数学 | 42篇 |
物理学 | 66篇 |
出版年
2023年 | 6篇 |
2022年 | 20篇 |
2021年 | 16篇 |
2020年 | 31篇 |
2019年 | 34篇 |
2018年 | 31篇 |
2017年 | 32篇 |
2016年 | 41篇 |
2015年 | 26篇 |
2014年 | 33篇 |
2013年 | 48篇 |
2012年 | 25篇 |
2011年 | 24篇 |
2010年 | 15篇 |
2009年 | 13篇 |
2008年 | 27篇 |
2007年 | 18篇 |
2006年 | 10篇 |
2005年 | 3篇 |
2004年 | 6篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 2篇 |
1996年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1987年 | 1篇 |
1985年 | 1篇 |
排序方式: 共有480条查询结果,搜索用时 15 毫秒
101.
102.
103.
Bayat Zeinab Saeedzadeh Elham Vahidfar Nasim Sadeghi Mahdi Farzenefar Saeed Daha Fariba Johari Salehi Yalda 《Journal of Radioanalytical and Nuclear Chemistry》2022,331(2):691-700
Journal of Radioanalytical and Nuclear Chemistry - Radiocolloides are essential for the detection of metastatic lymph nodes in breast cancer. In this study [67Ga]Ga-phytate, as an long-lived... 相似文献
104.
Shaabani A Farhangi E Rahmati A 《Combinatorial chemistry & high throughput screening》2006,9(10):771-776
Tetraheterocyclic benzimidazo[1,2-a]quinazolin-4(1H)-one and tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one were synthesized in relatively high yields by the condensation reaction of an aldehyde and a cyclic beta-diketone with 2-aminobenzothiazole, 2-aminobenzimidazole or 3-amino-1,2,4-triazole without using any catalyst under solvent-free conditions. 相似文献
105.
Francesca Parolini Elham Ataie Kachoie Giulia Leo Laura Civiero Luigi Bubacco Giorgio Arrigoni Francesca Munari Michael Assfalg Mariapina D'Onofrio Stefano Capaldi 《Angewandte Chemie (International ed. in English)》2023,62(50):e202310230
Post-translational modifications of Tau are emerging as key players in determining the onset and progression of different tauopathies such as Alzheimer's disease, and are recognized to mediate the structural diversity of the disease-specific Tau amyloids. Here we show that the E3 ligase CHIP catalyzes the site-specific ubiquitination of Tau filaments both in vitro and in cellular models, proving that also Tau amyloid aggregates are direct substrate of PTMs. Transmission electron microscopy and mass spectrometry analysis on ubiquitin-modified Tau amyloids revealed that the conformation of the filaments restricts CHIP-mediated ubiquitination to specific positions of the repeat domain, while only minor alterations in the structure of the fibril core were inferred using seeding experiments in vitro and in a cell-based tauopathy model. Overexpression of CHIP significantly increased the ubiquitination of exogenous PHF, proving that the ligase can interact and modify Tau aggregates also in a complex cellular environment. 相似文献
106.
In this research a novel and efficient procedure for the preparation of phosphonate derivatives using the reaction of 2,4-dihydroxyacetophenone, isopropenylacetylene, 2-amino-N-alkyl benzamide, dialkyl acetylenedicarboxylates and trimethyl phosphite or triphenyl phosphite in the presence of reusable 2D ZnO/Fe3O4 nanocomposites in water at room temperature was investigated. The 2D ZnO/Fe3O4 nanocomposites were synthesized using ionic liquid [OMIM]Br as a stabilizer and soft template. In addition, the power of antioxidant for some prepared compounds was studied using trapping of radicals by DPPH and a ferric reduction activity potential experiment. As a result, compound 6f displayed a noteworthy power for trapping of free radicals and 6b exhibited excellent reducing power compared with standards (BHT and TBHQ). Moreover, the antimicrobial power of some prepared quinazolinone phosphonates was proved by employing the disk diffusion experiment on two kinds of bacteria, Gram-positive and -negative bacteria. The obtained outcomes of disk diffusion test showed that these compounds prevented bacterial growth. Some advantages of this procedure are: short time of reaction, high yields of product and easy separation of catalyst and products. 相似文献
107.
Nouri Parouch Ahmad Koukabi Nadiya Abdous Elham 《Research on Chemical Intermediates》2020,46(7):3295-3310
Research on Chemical Intermediates - In the present study, a magnetically separable potent solid acid nanocatalyst with a facile preparation technique was fabricated via incorporation of fibroin as... 相似文献
108.
109.
This note makes a correction to the paper “Top local cohomology modules and Gorenstein injectivity with respect to a semidualizing module”. 相似文献
110.
Saied Saeed HosseinyDavarani Hamid Reza Moazami Elham Memarian Saeed Nojavan 《Electrophoresis》2016,37(2):339-346
Electromembrane extraction (EME) of model analytes was carried out using a virtually rotating supported liquid membrane (SLM). The virtual (nonmechanical) rotating of the SLM was achieved using a novel electrode assembly including a central electrode immersed inside the lumen of the SLM and five counter electrodes surrounding the SLM. A particular electronic circuit was designed to distribute the potential among five counter electrodes in a rotating pattern. The effect of the experimental parameters on the recovery of the extraction was investigated for verapamil (VPL), trimipramine (TRP), and clomipramine (CLP) as the model analytes and 2‐ethyl hexanol as the SLM solvent. The results showed that the recovery of the extraction is a function of the angular velocity of the virtual rotation. The best results were obtained at an angular velocity of 1.83 RadS?1 (or a rotation frequency of 0.29 Hz).The optimization of the parameters gave higher recoveries up to 50% greater than those of a conventional EME method. The rotating also allowed the extraction to be carried out at shorter time (15 min) and lower voltage (200 V) with respect to the conventional extraction. The model analytes were successfully extracted from wastewater and human urine samples with recoveries ranging from 38 to 85%. The RSD of the determinations was in the range of 12.6 to 14.8%. 相似文献