全文获取类型
收费全文 | 954篇 |
免费 | 87篇 |
国内免费 | 8篇 |
专业分类
化学 | 732篇 |
晶体学 | 1篇 |
力学 | 15篇 |
数学 | 188篇 |
物理学 | 113篇 |
出版年
2024年 | 2篇 |
2023年 | 22篇 |
2022年 | 21篇 |
2021年 | 44篇 |
2020年 | 60篇 |
2019年 | 64篇 |
2018年 | 21篇 |
2017年 | 22篇 |
2016年 | 58篇 |
2015年 | 60篇 |
2014年 | 45篇 |
2013年 | 57篇 |
2012年 | 71篇 |
2011年 | 81篇 |
2010年 | 53篇 |
2009年 | 66篇 |
2008年 | 62篇 |
2007年 | 56篇 |
2006年 | 42篇 |
2005年 | 38篇 |
2004年 | 27篇 |
2003年 | 21篇 |
2002年 | 15篇 |
2001年 | 8篇 |
2000年 | 5篇 |
1999年 | 7篇 |
1998年 | 1篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有1049条查询结果,搜索用时 15 毫秒
181.
Perfluoro‐Tagged Benzyloxycarbonyl Protecting Group and Its Application in Fluorous Biphasic Systems
The synthesis of a new perfluoro‐tagged benzyloxycarbonyl protecting group is reported, as well as its application in the parallel protection of amines. Isolation of the protected amines was performed by simple liquid‐liquid extraction between perfluorinated and organic solvents. Deprotection was achieved by standard hydrogenolysis. The novel protecting group was also applied to cyclization protocols leading to quinazoline‐2,4‐diones. These products were isolated by simple extraction procedures 相似文献
182.
Russell Whitesides Dominik Domin William A. Lester Jr. Michael Frenklach 《Proceedings of the Combustion Institute》2009,32(1):577-583
Reaction pathways are presented for hydrogen-mediated isomerization of a zigzag graphene edge containing a five-member carbon ring surrounded by six-member rings. A new reaction sequence in which this embedded five-member ring moves, or migrates, through the edge has been identified. The elementary steps of the pathways were analyzed using density functional theory (DFT). Rate coefficients were obtained by classical transition state theory utilizing the DFT energies, frequencies, and geometries. The results indicate that this new reaction sequence is competitive with the other important zigzag edge reactions allowing embedded five-member rings to move freely within a zigzag edge. The embedded rings have slight thermodynamic preference for the interior of the edge over the corner for large substrates. 相似文献
183.
Dominik Brands Jörg Schröder Axel Klawonn Oliver Rheinbach Dirk Böse Raimund Erbel 《PAMM》2009,9(1):75-78
Atherosclerosis has become one of the most frequent causes of death in the last decades. So the analysis and improvement of corresponding medical treatments, e.g., balloon-angioplasty or stenting, are significant tasks in the fields of biomechanics and biomedical engineering. One important component of the simulation of arterial walls, especially of atherosclerotically degenerated ones, is the knowledge of their anatomical and physiological composition. The intravascular ultrasound and the interpretation by the Virtual Histology provide cross-sectional images of the diseased arterial walls where the different components are characterized by color-coding. The topic of this contribution is the 3D reconstruction and discretization of the artery using these color-coded images and the biplane angiography. (© 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) 相似文献
184.
185.
Ivana Kiov Zdenk To
ík Milo Budínský Ondej imk Radek Liboska Dominik Rejman Ondej Pa
es Ivan Rosenberg 《Tetrahedron letters》2009,50(49):6745-6747
A straightforward procedure leading to the new phosphonylating reagent, methyl 4-toluenesulfonyloxymethylphosphonate, requiring no chromatographic purification is described. This stable reagent works with the same efficiency as dimethyl and other dialkyl esters for the introduction of an O-phosphonomethyl moiety while, in contrast to dimethyl ester, it does not cause any unwanted methylation of sensitive functionalities. Its utility for the alkylation of protected nucleosides in high yield is exemplified. 相似文献
186.
Annekathrin Seifert Dominik Scheid Gerald Linti Prof. Dr. Thomas Zessin 《Chemistry (Weinheim an der Bergstrasse, Germany)》2009,15(44):12114-12120
The gallium(I) derivative [Ga({N(dipp)CMe}2CH)] ( 1 ; dipp=2,6‐diisopropylphenyl) undergoes facile oxidative addition reactions with various element–hydrogen bonds including N? H, P? H, O? H, Sn? H, and H? H bonds. This was demonstrated by its reaction with triphenyltin hydride, ethanol, water, diethylamine, diphenylphosphane, and dihydrogen. All products were characterized by means of single‐crystal X‐ray structure determination, NMR spectroscopy, IR spectroscopy, and mass spectrometry. 相似文献
187.
Andrea Schuy Theo Woike Dominik Schaniel 《Journal of Sol-Gel Science and Technology》2009,50(3):403-408
Photoswitchable hybrid materials are successfully prepared by embedding guanidinium nitroprussides (GuNP, (CN3H6)2[Fe(CN)5NO]) into mesopores of transparent xerogel monoliths. The such prepared hybrid materials exhibit a higher photostability than
the corresponding GuNP solutions, whereby the chemical stability of the [Fe(CN)5NO]2−-anion in titania gel is nearly infinite. By irradiation with light in the blue-green spectral range one nitrosyl isomer is
formed by a 180° rotation of the NO ligand changing the Fe–NO into a Fe–ON coordination (SI), which is detected by the shift
of the ν(NO) stretching vibration from 1945 cm−1 (Fe–NO) to 1820 cm−1 (Fe–ON). Consequently there is enough space around the NO-ligand for such movement in xerogel mesopores. The embedding in
silica xerogels increases the achievable population of the isomeric nitrosyl configuration to about 15% with respect to a
single crystalline powder where only 9% are reached. 相似文献
188.
Natalya Hessenauer‐Ilicheva Alicja Franke Dr. Dominik Meyer Wolf‐D. Woggon Prof. Dr. Rudi van Eldik Prof. Dr. 《Chemistry (Weinheim an der Bergstrasse, Germany)》2009,15(12):2941-2959
Two new models for cytochrome P450 in which the thiolate axial ligand is replaced by an RSO3? group, form oxo‐iron(IV) porphyrin π‐cation radicals as sole oxidation products in “peroxo shunt” reactions (see scheme) independent of the nature of the employed solvent (polar or non‐polar) and electronic nature of the porphyrin rings.
189.
Dominik Nied Wim Klopper Prof. Dr. Frank Breher Prof. Dr. 《Angewandte Chemie (International ed. in English)》2009,48(8):1411-1416
Ge, whiz! A detailed study of the synthesis, structure, redox chemistry, and bonding properties of pentagerma[1.1.1]propellane ( 1 , see picture) examines fundamental aspects of the interactions between the bridgehead germanium atoms. DFT and CASSCF calculations unravel the biradicaloid characteristics of 1 , and preliminary reactivity studies indicate that 1 features some radical‐type behavior.
190.
The applicability of different concentration detection methods for online quantification of liposomes upon asymmetric flow field‐flow fractionation was investigated. Filter‐extruded egg phosphatidylcholine liposomes of different size were used. Online quantification using a differential refractive index (dRI) detector was found feasible for relatively high sample loads in the magnitude of 100 μg lipid (under the chosen fractionation conditions). UV–Vis detection of the turbidity of liposomes was ruled out as online detection method because turbidity increases with particle size and the signal is not only concentration but also particle‐size dependent. Staining of liposomes by Rhodamine phosphatidylethanolamine or Sudan Red and subsequent online UV–Vis detection at the absorption maximum of the dye enabled quantification with much higher sensitivity than dRI detection. Furthermore analyte loss and carry‐over phenomena upon repeated injection of varying liposome sample loads were studied using regenerated cellulose (RC) membranes as accumulation wall. It could be shown that RC membranes are prone to adsorption in case of very small sample loads (0.5 μg). This effect may be overcome by pre‐saturation of the membrane with sample loads of at least 2 μg. For higher sample loads adsorptive losses play a minor role. Recovery from pre‐saturated membranes reached approximately 100% and carry‐over was found negligible. 相似文献