全文获取类型
收费全文 | 950篇 |
免费 | 87篇 |
国内免费 | 8篇 |
专业分类
化学 | 728篇 |
晶体学 | 1篇 |
力学 | 15篇 |
数学 | 188篇 |
物理学 | 113篇 |
出版年
2024年 | 2篇 |
2023年 | 22篇 |
2022年 | 17篇 |
2021年 | 44篇 |
2020年 | 60篇 |
2019年 | 64篇 |
2018年 | 21篇 |
2017年 | 22篇 |
2016年 | 58篇 |
2015年 | 60篇 |
2014年 | 45篇 |
2013年 | 57篇 |
2012年 | 71篇 |
2011年 | 81篇 |
2010年 | 53篇 |
2009年 | 66篇 |
2008年 | 62篇 |
2007年 | 56篇 |
2006年 | 42篇 |
2005年 | 38篇 |
2004年 | 27篇 |
2003年 | 21篇 |
2002年 | 15篇 |
2001年 | 8篇 |
2000年 | 5篇 |
1999年 | 7篇 |
1998年 | 1篇 |
1997年 | 3篇 |
1996年 | 1篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有1045条查询结果,搜索用时 31 毫秒
121.
Dominik Stöckinger 《Hyperfine Interactions》2013,214(1-3):13-19
The impact of the muon magnetic moment measurement on physics beyond the Standard Model is briefly reviewed. Particular emphasis is given on the case of supersymmetry. The sensitivity of g ? 2 to supersymmetry parameters and the potential for model discrimination and parameter measurements is described. The interplay between LHC data on the Higgs boson, limits on new particles, and g ? 2 is discussed. 相似文献
122.
123.
124.
Let 𝒜 be a unital algebra and let ? be a unitary 𝒜-bimodule. We consider Jordan generalized derivations mapping from 𝒜 into ?. Our results on unitary algebras are applied to triangular algebras. In particular, we prove that any Jordan generalized derivation of a triangular algebra is a generalized derivation. 相似文献
125.
Synthetic folded insulin variants containing an ornithine‐hydroxylamine residue are readily modified in aqueous buffers by amide‐forming ligations with potassium acyltrifluoroborates (KATs). The synthetic insulin analogs were prepared by Fmoc‐SPPS, α‐ketoacid‐hydroxylamine (KAHA) ligation, and a prosthetic C‐peptide that delivers the correct disulfide pattern and allows facile incorporation at the B0 position of Glargine M2 of a new ornithine hydroxylamine protected with a photolabile group. The folded insulin is readily modified by photo‐deprotection followed by amide‐forming KAT ligation to give insulin variants labeled with dyes, lipids, and PEGs, as well as the formation of a covalent dimer. 相似文献
126.
Martin PichetteDrapeau Janet Bahri Dominik Lichte Lukas J. Gooßen 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(3):902-906
In the presence of a bimetallic Pd/Cu system with 1,10‐phenanthroline as the ligand and either air or N‐methylmorpholine N‐oxide as the oxidant, electron‐deficient benzoic acids undergo oxidative decarboxylative coupling with unprotected amines. This operationally simple aniline synthesis is widely applicable with respect to the amine and gives good yields, even on multigram scale. The orthogonality of this reaction to other Pd‐catalyzed cross‐couplings allows the concise synthesis of multisubstituted arenes by sequential C?C, C?Cl, and C?N functionalizations. Mechanistic investigations suggest the intermediacy of a hypervalent Pd species. 相似文献
127.
Dominik Jacob Kathrin Thüring Aurellia Galliot Virginie Marchand Adeline Galvanin Akif Ciftci Karin Scharmann Michael Stock Jean‐Yves Roignant Sebastian A. Leidel Yuri Motorin Raffael Schaffrath Roland Klassen Mark Helm 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(28):9666-9670
128.
Marc‐Andr Kasper Andreas Stengl Philipp Ochtrop Marcus Gerlach Tina Stoschek Dominik Schumacher Jonas Helma Martin Penkert Eberhard Krause Heinrich Leonhardt Christian P. R. Hackenberger 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(34):11757-11762
Requirements for novel bioconjugation reactions for the synthesis of antibody–drug conjugates (ADCs) are exceptionally high, since conjugation selectivity as well as the stability and hydrophobicity of linkers and payloads drastically influence the performance and safety profile of the final product. We report Cys‐selective ethynylphosphonamidates as new reagents for the rapid generation of efficacious ADCs from native non‐engineered monoclonal antibodies through a simple one‐pot reduction and alkylation. Ethynylphosphonamidates can be easily substituted with hydrophilic residues, giving rise to electrophilic labeling reagents with tunable solubility properties. We demonstrate that ethynylphosphonamidate‐linked ADCs have excellent properties for next‐generation antibody therapeutics in terms of serum stability and in vivo antitumor activity. 相似文献
129.
Mihael Erakovi Dominik Cin
i Kreimir Mol
anov Vladimir Stilinovi 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(44):15849-15853
The covalent nature of strong N?Br???N halogen bonds in a cocrystal ( 2 ) of N‐bromosuccinimide ( NBS ) with 3,5‐dimethylpyridine ( lut ) was determined from X‐ray charge density studies and compared to a weak N?Br???O halogen bond in pure crystalline NBS ( 1 ) and a covalent bond in bis(3‐methylpyridine)bromonium cation (in its perchlorate salt ( 3 ). In 2 , the donor N?Br bond is elongated by 0.0954 Å, while the Br???acceptor distance of 2.3194(4) is 1.08 Å shorter than the sum of the van der Waals radii. A maximum electron density of 0.38 e Å?3 along the Br???N halogen bond indicates a considerable covalent contribution to the total interaction. This value is intermediate to 0.067 e Å?3 for the Br???O contact in 1 , and approximately 0.7 e Å?3 in both N?Br bonds of the bromonium cation in 3 . A calculation of the natural bond order charges of the contact atoms, and the σ*(N1?Br) population of NBS as a function of distance between NBS and lut , have shown that charge transfer becomes significant at a Br???N distance below about 3 Å. 相似文献
130.
The complex permittivities of aqueous SDS solutions, with and without the addition of sodium chloride (NaCl), are measured in the frequency range from 200 MHz to 14 GHz. The SDS concentrations are chosen such that the SDS molecules aggregate to micelles. In this frequency range, the measured spectra allow for the identification of two different relaxation processes. That is, the relaxation of the water molecules at frequencies above 1 GHz and the micellar relaxation at frequencies lower than 1 GHz. It is found that the addition of NaCl to the system mostly affects the micellar relaxation process. In detail, the time constant as well as the amplitude of the relaxation decrease by adding NaCl. These effects are attributed to the change in the solution conductivity that changes the properties of the micelle's electrical double layer. We also extract the Dukhin number of the micelles as a function of surfactant and electrolyte content from the measurements. The Dukhin number is a dimensionless group that describes the influence of the surface conductivity on a phenomena. A regression between Dukhin numbers and free sodium ions is found so that all data collapses on a single curve independent of the surfactant concentration. The surface conductivity is a manifestation of the electrical double layer and we use the Bikerman equation to infer the zeta potential of the micelles. Comparison to literature data shows very good agreement and proves that dielectric relaxation spectroscopy can be engaged to infer the zeta potential of micelles. Abbreviations: CMC critical micelle concentration, DRS dielectric relaxation spectroscopy, EDL electrical double layer 相似文献