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91.
Ohne Zusammenfassung 相似文献
92.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Alexeev GD Alkhazov G Alton A Alverson G Alves GA Ancu LS Aoki M Arnoud Y Arov M Askew A Asman B Atramentov O Avila C Backusmayes J Badaud F Bagby L Baldin B Bandurin DV Banerjee S Barberis E Baringer P Barreto J Bartlett JF Bassler U Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Benitez JA Beri SB Bernardi G Bernhard R Bertram I Besançon M Beuselinck R Bezzubov VA Bhat PC Bhatnagar V Blazey G Blessing S Bloom K 《Physical review letters》2010,105(21):211803
We report results of a search for particles with anomalously high ionization in events with a high transverse energy jet and large missing transverse energy in 2.4 fb?1 of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron pp collider. Production of such particles (quirks) is expected in scenarios with extra QCD-like SU(N) sectors, and this study is the first dedicated search for such signatures. We find no evidence of a signal and set a lower mass limit of 107, 119, and 133 GeV for the mass of a charged quirk with strong dynamics scale Λ in the range from 10 keV to 1 MeV and N=2, 3, and 5, respectively. 相似文献
93.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Alexeev GD Alkhazov G Alton A Alverson G Alves GA Ancu LS Aoki M Arnoud Y Arov M Askew A Asman B Atramentov O Avila C Backusmayes J Badaud F Bagby L Baldin B Bandurin DV Banerjee S Barberis E Baringer P Barreto J Bartlett JF Bassler U Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Benitez JA Beri SB Bernardi G Bernhard R Bertram I Besançon M Beuselinck R Bezzubov VA Bhat PC Bhatnagar V Blazey G Blessing S Bloom K 《Physical review letters》2010,105(22):221802
We report a search for diphoton events with large missing transverse energy produced in pp collisions at √s=1.96 TeV. The data were collected with the D0 detector at the Fermilab Tevatron Collider and correspond to 6.3 fb(-1) of integrated luminosity. The observed missing transverse energy distribution is well described by the standard model prediction, and 95% C.L. limits are derived on two realizations of theories beyond the standard model. In a gauge-mediated supersymmetry breaking scenario, the breaking scale Λ is excluded for Λ<124 TeV. In a universal extra dimension model including gravitational decays, the compactification radius R(c) is excluded for R(c)(-1)<477 GeV. 相似文献
94.
Abazov VM Abbott B Acharya BS Adams M Adams T Alexeev GD Alkhazov G Alton A Alverson G Alves GA Ancu LS Aoki M Arov M Askew A Åsman B Atramentov O Avila C BackusMayes J Badaud F Bagby L Baldin B Bandurin DV Banerjee S Barberis E Baringer P Barreto J Bartlett JF Bassler U Bazterra V Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Beri SB Bernardi G Bernhard R Bertram I Besançon M Beuselinck R Bezzubov VA Bhat PC Bhatnagar V Blazey G Blessing S Bloom K Boehnlein A Boline D 《Physical review letters》2011,107(3):032001
We determine the fraction of tt events with spin correlation, assuming that the spin of the top quark is either correlated with the spin of the top antiquark as predicted by the standard model or is uncorrelated. For the first time we use a matrix-element-based approach to study tt spin correlation. We use tt → W+ b W- b → ?+ νb?- ν b final states produced in pp collisions at a center-of-mass energy sqrt(s)=1.96 TeV, where ? denotes an electron or a muon. The data correspond to an integrated luminosity of 5.4 fb(-1) and were collected with the D0 detector at the Fermilab Tevatron collider. The result agrees with the standard model prediction. We exclude the hypothesis that the spins of the tt are uncorrelated at the 97.7% C.L. 相似文献
95.
Abazov VM Abbott B Acharya BS Adams M Adams T Alexeev GD Alkhazov G Alton A Alverson G Alves GA Ancu LS Aoki M Arnoud Y Arov M Askew A Åsman B Atramentov O Avila C BackusMayes J Badaud F Bagby L Baldin B Bandurin DV Banerjee S Barberis E Baringer P Barreto J Bartlett JF Bassler U Bazterra V Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Beri SB Bernardi G Bernhard R Bertram I Besançon M Beuselinck R Bezzubov VA Bhat PC Bhatnagar V Blazey G Blessing S Bloom K Boehnlein A 《Physical review letters》2011,106(8):081801
We present a search for hypothetical vectorlike quarks in pp ? collisions at √s=1.96 TeV. The data were collected by the D0 detector at the Fermilab Tevatron Collider and correspond to an integrated luminosity of 5.4 fb(-1). We select events with a final state composed of a W or Z boson and a jet consistent with a heavy object decay. We observe no significant excess in comparison to the background prediction and set limits on production cross sections for vectorlike quarks decaying to W+jet and Z+jet. These are the most stringent limits to date for electroweak single vectorlike quark production at hadron colliders. 相似文献
96.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Alexeev GD Alkhazov G Alton A Alverson G Alves GA Ancu LS Aoki M Arnoud Y Arov M Askew A Åsman B Atramentov O Avila C BackusMayes J Badaud F Bagby L Baldin B Bandurin DV Banerjee S Barberis E Baringer P Barreto J Bartlett JF Bassler U Bazterra V Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Beri SB Bernardi G Bernhard R Bertram I Besançon M Beuselinck R Bezzubov VA Bhat PC Bhatnagar V Blazey G Blessing S Bloom K 《Physical review letters》2011,106(12):122001
Using 7.3 fb?1 of pp collisions collected by the D0 detector at the Fermilab Tevatron, we measure the distribution of the variable φ(η)*, which probes the same physical effects as the Z/γ* boson transverse momentum, but is less susceptible to the effects of experimental resolution and efficiency. A QCD prediction is found to describe the general features of the φ(η)* distribution, but is unable to describe its detailed shape or dependence on boson rapidity. A prediction that includes a broadening of transverse momentum for small values of the parton momentum fraction is strongly disfavored. 相似文献
97.
Johnson MC Hu Q Lingardo L Ferre RA Greasley S Yan J Kath J Chen P Ermolieff J Alton G 《Journal of computer-aided molecular design》2011,25(7):689-698
Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT pathway and to the activation of AGC family
protein kinases, including S6K, SGK, and PKC. Dysregulation of this pathway plays a key role in cancer cell growth, survival
and tumor angiogenesis. As such, inhibitors of PDK1 offer the promise of a new therapeutic modality for cancer treatment.
Fragment based drug screening has recently become a viable entry point for hit identification. In this work, NMR spectroscopy
fragment screening of PDK1 afforded novel chemotypes as orthogonal starting points from HTS screening hits. Compounds identified
as hits by NMR spectroscopy were tested in a biochemical assay, and fragments with activity in both assays were clustered.
The Pfizer compound file was mined via substructure and 2D similarity search, and the chemotypes were prioritized by ligand
efficiency (LE), SAR mining, chemical attractiveness, and chemical enablement of promising vectors. From this effort, an isoquinolone
fragment hit, 5 (IC50 870 μM, LE = 0.39), was identified as a novel, ligand efficient inhibitor of PDK1 and a suitable scaffold for further optimization.
Initially in the absence of crystallographic data, a fragment growing approach efficiently explored four vectors of the isoquinolone
scaffold via parallel synthesis to afford a compound with crystallographic data, 16 (IC50 41.4 μM, LE = 0.33). Subsequent lead optimization efforts provided 24 (IC50 1.8 μM, LE = 0.42), with greater than fivefold selectivity against other key pathway kinases. 相似文献
98.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Agelou M Agram JL Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Andeen T Anderson S Andrieu B Arnoud Y Arov M Askew A Asman B Assis Jesus AC Atramentov O Autermann C Avila C Badaud F Baden A Bagby L Baldin B Balm PW Banerjee P Banerjee S Barberis E Bargassa P Baringer P Barnes C Barreto J Bartlett JF Bassler U Bauer D Bean A Beauceron S Begalli M Begel M Bellavance A Beri SB Bernardi G Bernhard R Bertram I 《Physical review letters》2006,96(1):011801
We present a search for the standard model Higgs boson in H --> WW(*) decays with e+e-, e+/-mu-/+, and mu+mu- final states in pp collisions at a center-of-mass energy of square root of s = 1.96 TeV. The data, collected from April 2002 to June 2004 with the D0 detector, correspond to an integrated luminosity of 300-325 pb(-1), depending on the final state. The number of events observed is consistent with the expectation from backgrounds. Limits from the combination of all three channels on the Higgs boson production cross section times branching ratio sigma x BR(H --> WW(*) are presented. 相似文献
99.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Agelou M Agram JL Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Andeen T Anderson S Andrieu B Anzelc MS Arnoud Y Arov M Askew A Asman B Jesus AC Atramentov O Autermann C Avila C Ay C Badaud F Baden A Bagby L Baldin B Bandurin DV Banerjee P Banerjee S Barberis E Bargassa P Baringer P Barnes C Barreto J Bartlett JF Bassler U Bauer D Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Bellavance A 《Physical review letters》2006,97(16):161803
We report a search for the standard model (SM) Higgs boson based on data collected by the D0 experiment at the Fermilab Tevatron Collider, corresponding to an integrated luminosity of 260 pb(-1). We study events with missing transverse energy and two acoplanar b jets, which provide sensitivity to the ZH production cross section in the nunu[over]bb[over] channel, and to WH production when the lepton from the W-->lnu decay is undetected. The data are consistent with the SM background expectation, and we set 95% C.L. upper limits on sigma(pp[over]-->ZH/WH)xB(H-->bb[over]) from 3.4/8.3 to 2.5/6.3 pb, for Higgs-boson masses between 105 and 135 GeV. 相似文献
100.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Agelou M Agram JL Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Andeen T Anderson S Andrieu B Anzelc MS Arnoud Y Arov M Askew A Asman B Assis Jesus AC Atramentov O Autermann C Avila C Ay C Badaud F Baden A Bagby L Baldin B Bandurin DV Banerjee P Banerjee S Barberis E Bargassa P Baringer P Barnes C Barreto J Bartlett JF Bassler U Bauer D Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L Bellavance A 《Physical review letters》2006,97(12):121802
A search for the production of neutral Higgs bosons Phi decaying into tau(+)tau(-) final states in pp[over ] collisions at a center-of-mass energy of 1.96 TeV is presented. The data, corresponding to an integrated luminosity of approximately 325 pb(-1), were collected by the D0 experiment at the Fermilab Tevatron Collider. Since no excess compared to the expectation from standard model processes is found, limits on the production cross section times branching ratio are set. The results are combined with those obtained from the D0 search for Phib(b[over ])-->bb[over ]b(b[over ]) and are interpreted in the minimal supersymmetric standard model. 相似文献