Caiguo Gong  Harry W. Gibson 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》1997,109(21):2426-2428

  相似文献   

    

Christoph Gibson  Gbor A. G. Sulyok  Diane Hahn  Simon L. Goodman  Günter Hlzemann  Horst Kessler 《Angewandte Chemie (International ed. in English)》2001,40(1):165-169

  相似文献   

    

George J. P. Britovsek  Vernon C. Gibson  Sergio Mastroianni  Daniel C. H. Oakes  Carl Redshaw  Gregory A. Solan  Andrew J. P. White  David J. Williams 《欧洲无机化学杂志》2001,2001(2):431-437

The synthesis and characterisation of iron(II) dichloro complexes containing neutral tridentate nitrogen ligands of the type 2-arylaminoalkyl-6-aryliminoalkylpyridine [2-ArNHCR(Me)-6-ArN=CR]C₅H₃N (R = H, Ar = 2,6-iPr₂C₆H₃ or 2,4,6-Me₃C₆H₂; R = Me, Ar = 2,6-iPr₂C₆H₃)] and 2,6-bis(arylaminomethyl)pyridine [2,6-(ArNHCH₂)₂]C₅H₃N (Ar = 2,6-iPr₂C₆H₃) are described and their activity in ethylene polymerisation is compared with their 2,6-bis(aryliminoalkyl)pyridine analogues.  相似文献   

    

Susan E. Gibson  Andrea Stevenazzi 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2003,115(16):1844-1854

  相似文献   

    

Gibson SE  Ibrahim H  Steed JW 《Journal of the American Chemical Society》2002,124(18):5109-5116

Six X-ray crystal structures are reported, all containing substituted triphenylmethanol derivative 4 either alone or as its mono or bis(chromium tricarbonyl) complexes. All four chromium complexes studied crystallize with two independent molecules in the crystallographic asymmetric unit. It is demonstrated that from the X-ray crystal structure of the acentric racemic (+/-)-(1pR,1' 'R)(1pS,1' 'S)-[Cr(CO)(3)(eta(6)-t-BuC(6)H(3)(CMeOMe)CPh(2)OH)], (+/-)-3, it is possible to deduce the 4-fold helical structure of the chiral (-)-(1pR,1' 'R) isomer, (-)-3. The bimetallic derivatives demonstrate the ability to control intermolecular interactions by the positioning of relative stereochemistry.  相似文献   

    

Harry W. Gibson  William S. Bryant  Sang‐Hun Lee 《Journal of polymer science. Part A, Polymer chemistry》2001,39(12):1978-1993

Poly[(methyl acrylate)‐rotaxa‐(30‐crown‐10)] ( 5 ) and poly[(methyl methacrylate)‐rotaxa‐(30‐crown‐10)] ( 6 ) were synthesized by azobisisobutyronitrile‐initiated free‐radical bulk polymerizations of the respective monomers in the presence of 30‐crown‐10 ( 1 ; equimolar; 5 times the monomer mass). For 5 , 3.8 mass % (0.81 mol % with respect to the monomer) of the crown was incorporated versus 1.7 mass % (0.39 mol % with respect to the monomer) for 6 . Control reactions with 18‐crown‐6, which is to small to be threaded, showed that chain transfer to the crown ethers was detectable only for the acrylate but was relatively negligible and spectroscopically distinct. The threading yields were much higher with these systems than with polystyrene, most likely because of the greater compatibility of the crown ether with these polar monomers and polymers and the consequent ability to carry out the polymerizations homogeneously in the absence of added solvent; however, the threading process was still essentially statistical. Therefore, the polymerization of methacrylate monomers 8a – 8c based on tetraarylmethane moieties connected via diethyleneoxy or triethyleneoxy spacers was examined in the presence of 1 in the belief that the supramolecular semirotaxane monomer 9 formed statistically in situ could be captured more efficiently and produce higher threading yields, presumably of side‐chain polyrotaxanes, than the simple (meth)acrylate monomers. Azobisisobutyronitrile‐initiated polymerizations either neat or in toluene produced polyrotaxanes 10 with up to about 1.6 mass % and 2 mol % threaded crown ether, presumably trapped on the pendant stoppered side chains. Although primarily statistical in nature, the latter rotaxane syntheses afforded on a molar basis 3–7 times more efficient incorporation of 1 than styrene (0.33 mol %), methyl acrylate (0.81 mol %), or methyl methacrylate (0.39 mol %) monomers for the preparation of main‐chain polypseudorotaxanes and indeed even surpassed the 60‐crown‐20/polyacrylonitrile system (1.5 mol %). This was presumed to be due to the fact that the loss of the crown ether, once it was threaded onto the monomer to form 9 and the latter was polymerized, was either retarded (by the tetraphenylmethyl stopper in 10a ) or prevented completely [by tris(p‐t‐butylphenyl)phenylmethyl stoppers in 10b and 10c ]. © 2001 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 39: 1978–1993, 2001  相似文献   

    

Sebastian G. Spain  Matthew I. Gibson  Neil R. Cameron 《Journal of polymer science. Part A, Polymer chemistry》2007,45(11):2059-2072

Glycopolymers are receiving increasing interest due to their application in areas, such as glycomics, medicine, biotechnology, sensors, and separation science. Consequently, new methods for their synthesis are constantly being developed, with an increasing emphasis on the preparation of well-defined polymers and on the production of complex macromolecular architectures such as stars. This review covers recent developments in the synthesis of glycopolymers, with a particular emphasis on (i) the use of controlled radical polymerization to prepare well-defined glycopolymers from unprotected monomers and (ii) postpolymerization modification strategies using reactive polymer precursors (including “click” reactions). Recent work on the production of glycosylated polypeptides, which are under investigation as mimics of naturally occurring glycoproteins, is also included. The authors offer some suggestions as to future developments and remaining challenges in this topical area of polymer chemistry. © 2007 Wiley Periodicals, Inc. J Polym Sci PartA: Polym Chem45: 2059–2072, 2007  相似文献   

    

Susan E. Gibson  Cristina Lecci 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2006,118(9):1392-1405

  相似文献   

    

Wright P  Chassaing C  Cussans N  Gibson D  Green C  Gleave M  Jones R  Macrae P  Saunders K 《Biomedical chromatography : BMC》2006,20(6-7):585-596

Increased demand for assays for compounds at the early stages of drug discovery within the pharmaceutical industry has led to the need for open-access mass spectrometry systems for performing quantitative analysis in a variety of biological matrices. The open-access mass spectrometers described here are LC/MS/MS systems operated in 'multiple reaction monitoring' (MRM) mode to obtain the sensitivity and specificity required to quantitate low levels of pharmaceutical compounds in an excess of biological matrix. Instigation of these open-access systems has resulted in mass spectrometers becoming the detectors of choice for non-expert users, drastically reducing analytical method development time and allowing drug discovery scientists to concentrate on their core expertise of pharmacokinetics and drug metabolism. Setting up an open-access facility that effectively allows a user with minimal mass spectral knowledge to exploit the MS/MS capability of triple quadrupole mass spectrometers presents a significantly different challenge from setting up qualitative single stage mass spectrometry systems. Evolution of quantitative open access mass spectrometry within a pharmaceutical drug metabolism and pharmacokinetics group, from its beginnings as a single generic system to a series of specialist fully integrated walk-up facilities, is described.  相似文献   

    

Paul A. Cameron  Vernon C. Gibson  Derek J. Irvine 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2000,112(12):2225-2228

  相似文献