Is there stereoselectivity in spin trapping superoxide by 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide?

[reaction: see text] Ester-containing nitrones, including 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide 5, have been reported to be robust spin traps for superoxide (O2*-). Using a chiral column, we have been able to isolate the two enantiomers of nitrone 5. With enantiomerically pure nitrone 5a and 5b we explored whether one of these isomers was solely responsible for the EPR spectrum of aminoxyl 6. Data obtained demonstrate that the spin trapping of O2*- by nitrone 5a and nitrone 5b affords the identical EPR spectra and lifetimes in homogeneous aqueous solution and exhibits the same ratio of cis and trans isomers. Quantum chemical modeling in vacuo also finds no difference, aside from the expected optical activity, arising from the difference in stereochemistry.     

The Antibacterial Activity Mode of Action of Plantaricin YKX against Staphylococcus aureus

We aimed to evaluate the inhibitory effect and mechanism of plantaricin YKX on S. aureus. The mode of action of plantaricin YKX against the cells of S. aureus indicated that plantaricin YKX was able to cause the leakage of cellular content and damage the structure of the cell membranes. Additionally, plantaricin YKX was also able to inhibit the formation of S. aureus biofilms. As the concentration of plantaricin YKX reached 3/4 MIC, the percentage of biofilm formation inhibition was over 50%. Fluorescent dye labeling combined with fluorescence microscopy confirmed the results. Finally, the effect of plantaricin YKX on the AI-2/LuxS QS system was investigated. Molecular docking predicted that the binding energy of AI-2 and plantaricin YKX was −4.7 kcal/mol and the binding energy of bacteriocin and luxS protein was −183.701 kcal/mol. The expression of the luxS gene increased significantly after being cocultured with plantaricin YKX, suggesting that plantaricin YKX can affect the QS system of S. aureus.     

Nonlinear Modeling Study of Aerodynamic Characteristics of an X38-like Vehicle at Strong Viscous Interaction Regions

Strong viscous interaction and multiple flow regimes exist when vehicles fly at high altitude and high Mach number conditions. The Navier–Stokes(NS) solver is no longer applicable in the above situation. Instead, the direct simulation Monte Carlo (DSMC) method or Boltzmann model equation solvers are usually needed. However, they are computationally more expensive than the NS solver. Therefore, it is of great engineering value to establish the aerodynamic prediction model of vehicles at high altitude and high Mach number conditions. In this paper, the hypersonic aerodynamic characteristics of an X38-like vehicle in typical conditions from 70 km to 110 km are simulated using the unified gas kinetic scheme (UGKS), which is applicable for all flow regimes. The contributions of pressure and viscous stress on the force coefficients are analyzed. The viscous interaction parameters, Mach number, and angle of attack are used as independent variables, and the difference between the force coefficients calculated by UGKS and the Euler solver is used as a dependent variable to establish a nonlinear viscous interaction model between them in the range of 70–110 km. The evaluation of the model is completed using the correlation coefficient and the relative orthogonal distance. The conventional viscous interaction effect and rarefied effect are both taken into account in the model. The model can be used to quickly obtain the hypersonic aerodynamic characteristics of X38-like vehicle in a wide range, which is meaningful for engineering design.     

低温制备≥99.5%多晶氧化铝陶瓷

本文通过引入稀土氧化物Y2O3、Tm2O3为烧结助剂低温制备了氧化铝含量大于99.5;的多晶氧化铝陶瓷.实验表明:稀土氧化物的加入能够明显降低99.5;多晶氧化铝陶瓷的烧结温度,提高致密度.Y2O3、Tm2O3混合烧结助剂与单一稀土氧化物的烧结助剂相比能够明显抑制晶粒的生长,促进晶粒的均匀发育.当Y2O3+Tm2O3的含量为0.3;质量分数时,99.5;多晶氧化铝陶瓷的相对密度可达99.2;理论密度,抗弯强度为533MPa,显微硬度为17.2GPa.陶瓷断裂主要以穿晶断裂为主.     

壳层厚度对骨架Fe@HZSM-5核壳催化剂费托合成催化性能的影响

在不同的水热合成时间下,以铁铝合金为铁源和铝源,四丙基氢氧化铵为分子筛的模板剂和抽提合金中的铝的碱,一步制得了以骨架铁为核、不同厚度的HZSM-5分子筛为壳的Raney Fe@HZSM-5催化剂.采用元素分析、氮物理吸附、X射线粉末衍射、氨脱附、扫描电子显微镜等手段,考察了水热时间对催化剂基本物化性质的影响.随着水热时...     

MAGNETOMECHANICAL BEHAVIORS OF GIANT MAGNETOSTRICTIVE MATERIALS

The Laves phase alloy Tb-Dy-Fe, commercially known as Terfenol-D, exhibits the giant room-temperature magnetostriction at moderate field strength of a few kOe due to its combination of high magnetostriction and low magnetocrystalline anisotropic energy. Thus, this pseudobinary rare earth iron compound has found quite a number of applications such as in magnetomechanical transducers, actuators and adaptive vibration control systems. The simultaneous measurements of magnetostriction and magnetization at various fixed compressive pre-stresses applied in the axial direction for Tb0.3Dy0.7Fe1.95 samples are presented. The results show that the magnetostriction increases with increasing compressive stress until it reaches 1742 ×10^6 under 25 MPa, so does the coercive magnetic field. And the hysteresis loop area for magnetization and magnetostriction also increases with the increment of applied compressive stresses. But the maximum magnetic susceptibility χ（dM/dH） is obtained under zero stress field and the strain derivative dλ/dH increases to the highest amplitude of 0.039×10^-6 A^-1m at a stress level of 5 MPa. In the strain versus magnetization intensity curve, the initial fiat stage mainly consisting of a 180° domain wall motion becomes shorter with increasing stress. It means more initial domains are driven to the transversal direction under the compressive stress before magnetization, which is consistent with the improvement of the magnetostriction.     

顺式氰戊菊酯与牛血清白蛋白相互作用的荧光光谱研究

用荧光光谱法研究了在生理pH值条件下杀虫剂顺式氰戊菊酯与牛血清白蛋白(BSA)的相互作用。结果表明:顺式氰戊菊酯对BSA的荧光有较强的猝灭作用,该猝灭属于静态猝灭。根据猝灭结果求得了不同温度下顺式氰戊菊酯与牛血清白蛋白作用的结合位点数、结合常数及反应热力学参数,并据此推测了它们之间主要的相互作用力为疏水作用力。还用同步荧光光谱法探讨了顺式氰戊菊酯对BSA构象的影响。     

Comparative study on transport properties of N-, P-, and As-doped SiC nanowires: Calculated based on first principles

According to the one-dimensional quantum state distribution, carrier scattering, and fixed range hopping model, the structural stability and electron transport properties of N-, P-, and As-doped SiC nanowires(N-SiCNWs, P-SiCNWs, and As-SiCNWs) are simulated by using the first principles calculations. The results show that the lattice structure of NSiCNWs is the most stable in the lattice structures of the above three kinds of doped SiCNWs. At room temperature,for unpassivated SiCNWs, the doping effect of P and As are better than that of N. After passivation, the conductivities of all doped SiCNWs increase by approximately two orders of magnitude. The N-SiCNW has the lowest conductivity. In addition, the N-, P-, As-doped SiCNWs before and after passivation have the same conductivity–temperature characteristics,that is, above room temperature, the conductivity values of the doped SiCNWs all increase with temperature increasing.These results contribute to the electronic application of nanodevices.     

Oscillation of coercivity between positive and negative in MnxGe1-x：H ferromagnetic semiconductor films

Amorphous MnxGe1-x :H ferromagnetic semiconductor films prepared in mixed Ar with 20% H2 by magnetron cosputtering show global ferromagnetism with positive coercivity at low temperatures. With increasing temperature, the coercivity of MnxGe1-x :H films first changes from positive to negative, and then back to positive again, which was not found in the corresponding MnxGe1-x and other ferromagnetic semiconductors before. For Mn0.4Ge0.6 :H film, the inverted Hall loop is also observed at 30 K, which is consistent with the negative coercivity. The negative coercivity is explained by the antiferromagnetic exchange coupling between the H-rich ferromagnetic regions separated by the H-poor non-ferromagnetic spacers. Hydrogenation is a useful method to tune the magnetic properties of MnxGe1-x films for the application in spintronics.