Europium-directed self-assembly of a luminescent supramolecular gel from a tripodal terpyridine-based ligand

Eu(III), the last piece in the puzzle: Europium-induced self-assembly of ligands having a C(3)-symmetrical benzene-1,3,5-tricarboxamide core results in the formation of luminescent gels. Supramolecular polymers are formed through hydrogen bonding between the ligands. The polymers are then brought together into the gel assembly through the coordination of terpyridine ends by Eu(III) ions (blue dashed arrow: distance between two ligands in the strand direction).     

Chiral (2,5)Pyrido[74]allenoacetylenic Cyclophanes: Synthesis and Characterization

Chiral pyridoallenophanes! The synthesis and characterization of chiral acetylenic pyridoallenophanes along with 2,4‐ and 2,5‐pyridyl[Re(CO)₄LBr] complexes are reported. The relative configurations of the four stereoisomers have been unambiguously assigned. Chromatographic resolution of the racemate of the C₄ stereoisomer was accomplished and mirror‐image CD spectra have been obtained (see figure).

     

A Clear‐Cut Example of Selective BpinBdan Activation and Precise Bdan Transfer on Boron Conjugate Addition

Activating the non‐symmetrical Bpin?Bdan diboron reagent with alkoxide leads to the formation of two possible adducts: MeO^?→Bpin?Bdan or MeO^?→Bdan?Bpin. Experimental and theoretical investigation confirms that the MeO^?→Bpin interaction is preferred and thus selective formation of a C?Bdan bond upon reaction with an activated C?C bond.     

Fluorescence intensity ratio technique for Sm3+ doped calibo glass

The most promising fluorescence based temperature sensing technique has been employed. The effect of variation of the temperature on the fluorescence intensity of the two bands, specially coming from the two closed levels to a common lower level in Sm3+ doped calibo glass monitored using 476.5nm line of Ar+ laser and inferred that the present system can be used as a temperature sensor.     

Carbon nanotube field effect transistors for the fast and selective detection of human immunoglobulin G

We report a field effect transistor (FET) based on a network of single-walled carbon nanotubes (SWCNTs) which can selectively detect human immunoglobulin G (HIgG). HIgG antibodies, which are strongly adsorbed onto the walls of the SWCNTs, are the basic elements of the recognition layer. The non-specific binding of proteins and the effects of other interferences are avoided by covering the non-adsorbed areas of the SWCNTs with Tween 20. The selectivity of the sensor has been tested against bovine serum albumin (BSA), the most abundant protein in plasma. HIgG in aqueous solution with concentrations from 1.25 mg L(-1) (8 nM) can be readily detected with response times of about 10 min. The SWCNT networks that form the basis of the sensor are easily grown by chemical vapour deposition. Silver screen-printed electrodes make the sensor quick to build. The sensitivity obtained with this sensor is similar to other FET devices based on SWCNTs built using much more complicated lithography processes. Moreover, the sensor is a reagentless device that does not need labels to detect HIgG.     

Intriguing behavior of cinchona alkaloids in the enantioselective organocatalytic hydroxyamination of alpha-substituted-alpha-cyanoacetates

The cinchona alkaloid quinine promotes the enantioselective nitroso-aldol reaction between alpha-aryl-alpha-cyanoacetates and nitrosobenzene to give the hydroxyamination products with total chemoselectivity. Treatment of the reaction mixture with Zn/AcOH affords the corresponding amines in high yield and moderate enantioselectivity. An unusual effect on the enantioselectivity was observed with the catalyst loading and solvent. A reductive protocol allows the construction of an optically active 1,2-diamine moiety bearing a quaternary center.     

Synthesis and photophysical properties of fullerene-phthalocyanine-porphyrin triads and pentads

The synthesis and photophysical properties of several fullerene-phthalocyanine-porphyrin triads (1-3) and pentads (4-6) are described. The three photoactive moieties were covalently connected in an one-step synthesis through 1,3-dipolar cycloaddition to C(60) of the corresponding azomethine ylides generated in situ by condensation reaction of a substituted N-porphyrinylmethylglycine derivative and an appropriated formyl phthalocyanine or a diformyl phthalocyanine derivative, respectively. ZnP-C(60)-ZnPc (3), (ZnP)(2)-ZnPc-(C(60))(2) (6), and (H(2)P)(2)-ZnPc-(C(60))(2) (5) give rise upon excitation of their ZnP or H(2)P components to a sequence of energy and charge-transfer reactions with, however, fundamentally different outcomes. With (ZnP)(2)-ZnPc-(C(60))(2) (6) the major pathway is an highly exothermic charge transfer to afford (ZnP)(ZnP(.+))-ZnPc-(C(60)(.-))(C(60)). The lower singlet excited state energy of H(2)P (i.e., ca. 0.2 eV) and likewise its more anodic oxidation (i.e., ca. 0.2 V) renders the direct charge transfer in (H(2)P)(2)-ZnPc-(C(60))(2) (5) not competitive. Instead, a transduction of singlet excited state energy prevails to form the ZnPc singlet excited state. This triggers then an intramolecular charge transfer reaction to form exclusively (H(2)P)(2)-ZnPc(.+)-(C(60)(.-))(C(60)). A similar sequence is found for ZnP-C(60)-ZnPc (3).     

Vehicle and crew scheduling for urban bus lines

A solution to the urban transportation problem is given by vehicle and crew schedules. These schedules must meet the passenger demand and satisfy technical and contractual restrictions stemming from the daily operation of the lines, while optimizing some measure of operational cost. This work describes a computational tool developed to solve the urban transportation problem in the large metropolitan area of São Paulo, Brazil. The techniques used are based on integer programming models coupled with heuristics. The former produces good feasible solutions, and the latter improves the quality of the final solutions. While the operational and labor restrictions are specific to the city of São Paulo, the same ideas can inspire similar approaches for solving the urban transportation problem arising in other metropolitan areas.