Effects of particle packing on the sintered microstructure

The sintering process is shown to be critically dependent on particle-packing density and porosity uniformity. Sintering experiments were conducted on compacts consisting of monodisperse, spherical TiO₂ particles. Densification kinetics and microstructure evolution for two initial packing densities, 55% and 69% of theoretical, were investigated. The lower-density compacts sintered rapidly to theoretical density, yet improved particle-packing density and uniformity significantly enhanced densification.     

Perturbation calculation of correlation energies for polyatomic molecules I. Initial results

The calculation of correlation energies for polyatomic molecules is discussed. Four second-order perturbation expressions are considered; only the simplest, a Rayleigh-Schroedinger expansion with the Moller-Plesset partitioning of the Hamiltonian is invariant to an arbitrary mixing of degenerate orbitals and has the correct dependence on the number of particles. In the absence of degeneracies an iterative Brillouin-Wigner method is proposed. Calculations predict that correlation effects favor the non-classical form of carbonium ions.     

Chemical ionization mass spectrometry. i-Butane reactant gas modified by ethanolamine or ethylenediamine

1,2-Diaminoethane and 2-aminoethanol-1 were added to the isobutane plasma of a chemical ionization mass spectrometer. The resulting reactant gas mixture did not react with additives containing a single oxygen functional group. Addition reactions were observed with some additives containing multiple oxygen functions. Additives containing nitrogen functions were protonated by the reactant mixture. The relative proportion of protonation to addition depended on the ability of the additive to chelate the reactant ion and on the basicity of the additive. This use of 1,2-diaminoethane and 2-aminoethanol-1 provides a convenient method of varying the reactivity of the plasma in a chemical ionization source.     

Generation and reactions of azaxylylenes

Azaxylylenes produced by flash vacuum pyrolysis of 2-aminobenzyl alcohols, dihydrobenzoxazinones and dihydrobenzoxazines undergo intramolecular cyclisation, H-shifts or Diels-Alder reactions, depending on their substituents.     

Commercial production of125I-Fibrinogen injection

In 1975 Health Protection Branch approval was received to distribute¹²⁵I-Fibrinogen Injection. Since that time over 30,000 vials of this drug have been prepared and used in the detection of venous thrombosis. Diagnosis of venous thrombosis with fibrinogen leg scanning depends on the incorporation of¹²⁵I-Fibrinogen into the thrombus, which is then detected by measuring the consequent increase of overlying surface radioactivity using a small Na(TI) detector. The preparation of the drug relies on careful donor selection to minimize the chance of transmitting hepatitis. Careful separation of the fibrinogen is necessary to ensure that a high concentration of clottable protein is available for iodination. Fibrinogen having a clottable protein content in excess of 80% is iodinated using the ICl method. This product must have a consistent high quality. The control procedures used to examine the quality of each batch are described.     

Bestimmung von Corticosteroiden im Blut durch Doppelmarkierung und Messung von 14C und 3H in der Gasphase

Ohne ZusammenfassungAuszug aus der Dissertation Reinhard Ködding, Technische Hochschule München 1961.