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11.
Measuring the fermion Yukawa coupling constants is important for understanding the origin of the fermion masses and their relationship with spontaneously electroweak symmetry breaking.In contrast,some new physics(NP)models change the Lorentz structure of the Yukawa interactions between standard model(SM)fermions and the SM-like Higgs boson,even in their decoupling limit.Thus,the precise measurement of the fermion Yukawa interactions is a powerful tool of NP searching in the decoupling limit.In this work,we show the possibility of investigating the Lorentz structure of the bottom-quark Yukawa interaction with the 125 GeV SM-like Higgs boson for future e^+e^- colliders.  相似文献   
12.
Dual-specific tyrosine phosphorylation regulated kinase 1 (DYRK1A) has been regarded as a potential therapeutic target of neurodegenerative diseases, and considerable progress has been made in the discovery of DYRK1A inhibitors. Identification of pharmacophoric fragments provides valuable information for structure- and fragment-based design of potent and selective DYRK1A inhibitors. In this study, seven machine learning methods along with five molecular fingerprints were employed to develop qualitative classification models of DYRK1A inhibitors, which were evaluated by cross-validation, test set, and external validation set with four performance indicators of predictive classification accuracy (CA), the area under receiver operating characteristic (AUC), Matthews correlation coefficient (MCC), and balanced accuracy (BA). The PubChem fingerprint-support vector machine model (CA = 0.909, AUC = 0.933, MCC = 0.717, BA = 0.855) and PubChem fingerprint along with the artificial neural model (CA = 0.862, AUC = 0.911, MCC = 0.705, BA = 0.870) were considered as the optimal modes for training set and test set, respectively. A hybrid data balancing method SMOTETL, a combination of synthetic minority over-sampling technique (SMOTE) and Tomek link (TL) algorithms, was applied to explore the impact of balanced learning on the performance of models. Based on the frequency analysis and information gain, pharmacophoric fragments related to DYRK1A inhibition were also identified. All the results will provide theoretical supports and clues for the screening and design of novel DYRK1A inhibitors.  相似文献   
13.
An efficient method is proposed for modeling time harmonic acoustic propagation in a nonuniform lined duct without flow. The lining impedance is axially segmented uniform, but varies circumferentially. The sound pressure is expanded in term of rigid duct modes and an additional function that carries the information about the impedance boundary. The rigid duct modes and the additional function are known a priori so that calculations of the true liner modes, which are difficult, are avoided. By matching the pressure and axial velocity at the interface between different uniform segments, scattering matrices are obtained for each individual segment; these are then combined to construct a global scattering matrix for multiple segments. The present method is an improvement of the multimodal propagation method, developed in a previous paper [Bi et al., J. Sound Vib. 289, 1091-1111 (2006)]. The radial rate of convergence is improved from O(n(-2)), where n is the radial mode indices, to O(n(-4)). It is numerically shown that using the present method, acoustic propagation in the nonuniform lined intake of an aeroengine can be calculated by a personal computer for dimensionless frequency K up to 80, approaching the third blade passing frequency of turbofan noise.  相似文献   
14.
Bi Qiao  Fang Jin-Qing 《Physica A》2007,383(2):753-762
The general formulas of the network for the power exponents of the degree distribution and the entropy are presented based on an open Liouville equation for the driven network. The proposed harmonious unifying hybrid preferential models (HUHPM) have been studied using the obtained formalism, in which the simulating results are quite consistent with the theoretical results.  相似文献   
15.
A numerical method with renormalization group transformation is used to study the scaling properties of phonon spectrum and its relevant state of one-dimensional quasiperiodic lattice which is constructed by reduced map. We find that the phonon spectrum at finite gaps' edges in the binary chain Fibonacci model is a Cantor-like set spectrum. The spectrum is singularly continuous and the state is a critical state.  相似文献   
16.
We report a detailed characterization of the magnetism and AC transport in single crystals of the organic conductor -(BEDT-TTF)2Cu[N(CN)2]Cl by means of magnetic anisotropy measurements and low-frequency dielectric spectroscopy. Magnetic anisotropy obeys Curie-Weiss law with negative Curie-Weiss temperature in the temperature range 300 K-70 K. An antiferromagnetic transition with concomitant canted antiferromagnetic state is established at 22 K. A large hysteresis in the spin-flop transition and magnetic field reversal of the weak ferromagnetic magnetization are documented for the first time. A broad dielectric relaxation mode of moderate strength () emerges at 32 K, and weakens with temperature. The mean relaxation time, much larger than that expected for single-particle excitations, is thermally activated in a manner similar to the DC conductivity and saturates below 22 K. These features suggest the origin of the broad relaxation as an intrinsic property of the weak ferromagnetic ground state. We propose a charged domain wall in a random ferromagnetic domain structure as the relaxation entity. We argue that the observed features might be well described if Dzyaloshinsky-Moriya interaction is taken into account. A Debye relaxation with similar temperature dependence was also observed and seems to be related to an additional ferromagnetic-like, most probably, field-induced phase. We tentatively associate this phase, whose tiny contribution was sample dependent, with a Cu2+ magnetic subsystem. Received 15 June 1998 and Received in final form 1 February 1999  相似文献   
17.
Diversity being inherent in classifiers is widely acknowledged as an important issue in constructing successful classifier ensembles. Although many statistics have been employed in measuring diversity among classifiers to ascertain whether it correlates with ensemble performance in the literature, most of these measures are incorporated and explained in a non-evidential context. In this paper, we provide a modelling for formulating classifier outputs as triplet mass functions and a uniform notation for defining diversity measures. We then assess the relationship between diversity obtained by four pairwise and non-pairwise diversity measures and the improvement in accuracy of classifiers combined in different orders by Demspter’s rule of combination, Smets’ conjunctive rule, the Proportion and Yager’s rules in the framework of belief functions. Our experimental results demonstrate that the accuracy of classifiers combined by Dempster’s rule is not strongly correlated with the diversity obtained by the four measures, and the correlation between the diversity and the ensemble accuracy made by Proportion and Yager’s rules is negative, which is not in favor of the claim that increasing diversity could lead to reduction of generalization error of classifier ensembles.  相似文献   
18.
X.C. Lu  J.H. Zhu  Z.H. Bi 《Solid State Ionics》2009,180(2-3):265-270
Composite materials of YSZ (yttria-stabilized zirconia) with various Ni–Fe alloys were synthesized and evaluated as the solid oxide fuel cell (SOFC) anode using a 200-µm thick YSZ electrolyte as support and YSZ +La0.8Sr0.2MnO3 (LSM) as cathode. The single cell with the YSZ + Ni0.75Fe0.25 anode exhibited the highest performance among all the investigated cells, e.g. a peak power density of 403, 337, 218 and 112 mW/cm2 was achieved with H2 fuel at 900, 850, 800 and 750 °C, respectively. The composite anode with the Ni0.75Fe0.25 alloy also had the lowest polarization resistance of 0.55 Ω·cm2 at 800 °C among all the alloy compositions, indicating that this specific alloy offered a better anode composition than pure Ni. The possible mechanism for the improved performance of Ni with the Fe alloying addition towards H2 oxidation was discussed.  相似文献   
19.
杨必成 《数学学报》2006,49(3):559-566
本文引入单参数λ,利用β函数,建立Hardy-Hilbert不等式与Mulholland不等式的一个具有最佳常数因子的联系式.作为应用,给出它的等价形式及一些特殊结果.  相似文献   
20.
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