FRET-induced nanomolar detection of Fe based on cinnamaldehyde-rhodamine derivative

A new dimethylaminocinnamaldehyde linked rhodamine based fluorescence receptor 3 is synthesized which shows fluorescence resonance energy transfer in the presence of Fe²⁺ ions, thus enhancing rational partition in between donor and acceptor emissions and permitting separated measurement of emissions of both fluorophores.     

Self-assembly and sensor response of photosynthetic reaction centers on screen-printed electrodes

Photosynthetic reaction centers were immobilized onto gold screen-printed electrodes (Au-SPEs) using a self-assembled monolayer (SAM) of mercaptopropionic acid (MPA) which was deliberately defective in order to achieve effective mediator transfer to the electrodes. The pure Photosystem II (PS II) cores from spinach immobilize onto the electrodes very efficiently but fair badly in terms of photocurrent response (measured using duroquinone as the redox mediator). The cruder preparation of PS II known as BBY particles performs significantly better under the same experimental conditions and shows a photocurrent response of 20-35 nA (depending on preparation) per screen-printed electrode surface (12.5mm(2)). The data was corroborated using AFM, showing that in the case of BBY particles a defective biolayer is indeed formed, with grooves spanning the whole thickness of the layer enhancing the possibility of mass transfer to the electrodes and enabling biosensing. In comparison, the PS II core layer showed ultra-dense organization, with additional formation of aggregates on top of the single protein layer, thus blocking mediator access to the electrodes and/or binding sites. The defective monolayer biosensor with BBY particles was successfully applied for the detection of photosynthesis inhibitors, demonstrating that the inhibitor binding site remained accessible to both the inhibitor and the external redox mediator. Biosensing was demonstrated using picric acid and atrazine. The detection limits were 1.15 nM for atrazine and 157 nM for picric acid.     

Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides

A fast and efficient nickel-catalysed iodination reaction of aryl and heteroaryl bromides has been developed. The transformation was found to be general for a wide range of substrates and was used for the synthesis of iodo-PK11195, an imaging agent of Alzheimer's disease and iniparib, a compound used in the treatment of breast cancer.     

Naphthalimide appended rhodamine derivative: through bond energy transfer for sensing of Hg2+ ions

A naphthalimide appended rhodamine based fluorescent chemosensor '1' is synthesized which undergoes through bond energy transfer in the presence of Hg(2+) ions in mixed aqueous media.     

Interferometry of direct photons in central 208Pb + 208Pb collisions at 158A GeV

Two-particle correlations of direct photons were measured in central 208Pb+208Pb collisions at 158A GeV. The invariant interferometric radii were extracted for 100相似文献   

Dielectric and impedance measurements on (1−x)Ba(Fe1/2Ta1/2)O3-xBa(Zn1/3Ta2/3)O3 ceramics

In this work, ((1−x)Ba(Fe_1/2Ta_1/2)O₃-xBa(Zn_1/3Ta_2/3)O₃), ((1−x)BFT-xBZT) ceramics with x = 0.00–0.12 were synthesized by the solid–state reaction method. X-ray diffraction data revealed that both the powders and ceramics were of a pure-phase cubic perovskite structure. All ceramics showed large dielectric constants. For the x = 0.12 sample, a very high dielectric constant (>20,600) was observed. A lowering in the dielectric loss compared to pure BFT ceramics was observed with the BZT addition. The impedance measurements indicated that BZT has a strong effect on the bulk grain and grain boundary resistance of BFT ceramics. These results are in agreement with the measured dielectric properties. Based on dielectric and impedance results, (1−x)BFT-xBZT ceramics could be of great interest for high performance dielectric materials applications due their giant dielectric constant behavior.     

A continuum based modelling approach for adhesively bonded piezo-transducers for EMI technique

In the electro-mechanical impedance (EMI) technique, which is based on induced strain actuation through piezoelectric ceramic (PZT) patch, the knowledge of shear stress distribution in the adhesive bond layer between the patch and the host structure is very pertinent for reliable health monitoring of structures. The analytical derivation of continuum based shear lag model covered in this paper aims to provide an improved and more accurate model for shear force interaction between the host structure and the PZT patch (assumed square for simplicity) through the adhesive bond layer, taking care of all the piezo, structural and adhesive effects rigorously and simultaneously. Further, it eliminates the hassle of determining the equivalent impedance of the structure and the actuator separately, as required in the previous models, which was approximate in nature. The results are compared with the previous models to highlight the higher accuracy of the new approach. Based on the new model, a continuum based interaction term has been derived for quantification of the shear lag and inertia effects.