Study of the π+π+π-π- system centrally 0 produced by incident π+ andp beams at 85 GeV/c

The reactions π⁺ p→π⁺(π⁺π⁺π^-π^-)p andpp→p(π⁺π⁺π^-π^-)p, where the (π⁺ π⁺ π^- π^-) system is centrally produced have been studied at 85 GeV/c. The π⁺π⁺π^-π^- mass spectrum shows evidence for thef ₁ (1285) meson with a mass of 1278±2 MeV and width 41±12 MeV which decays mainly through ρ⁰(770)π⁺π^-. Thef ₁(1285) is also observed in the ηπ⁺π^- channel. There is no significant evidence for ηππ or 4π decay modes of thef ₁(1420). The ρ⁰ρ⁰ production is found to be small. A Dalitz plot analysis of the 3π system shows evidence fora ₂ (1320) production and for a large contribution of theJ ^PC=1⁺⁺ ρπ wave.     

The reaction of C2F5 radicals with H2S

The reaction of C₂F₅ radicals with H₂S was studied over the range 1°?123°C using C₂F₅ radicals generated by photolysis of perfluoropropionic anhydride. The rate constant k_H for reaction (2) is given by where θ = 2.303RT/cal mole^?1. The relevance of this result to conflicting published data on the analogous reaction between CF₃ radicals and H₂S is discussed. It is concluded that there is little difference in the Arrhenius parameters for reaction of CF₃ and C₂F₅ radicals with H₂S.     

The photochemistry of hexafluoroacetylacetone in the vapour phase. Occurrence of a novel HF elimination reaction

Photolysis of the vapour of hexafluoroacetylacetone HFAA in its enolic form involves decomposition by two independent primary processes, one of which is a novel elimination of HF giving 2,2-difluoro-2,3-dihydro-5-trifluoromethylfuran-3-one: The HF is not vibrationally excited. Photolysis of the cyclic product of reaction (5) yields CF₂ radicals which, if HFAA is present, undergo an insertion into the enolic OH bond, (9) The infrared, ultraviolet, nuclear magnetic resonance, and mass spectra of HFAA and of the products of reactions (5) and (6) have been measured. Approximate quantum yields for reactions (1) and (5) have been obtained. Both ?₁ and ?₅ depend on pressure and the ratio ?₁/?₅ increases with temperature and decreased wavelength of photolysing light. It is proposed that the ratio ?₁/?₅ increases as the vibrational energy of electronically excited HFAA increases.     

Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression

Background  

In the adult hippocampus, the granule cell layer of the dentate gyrus is a heterogeneous structure formed by neurons of different ages, morphologies and electrophysiological properties. Retroviral vectors have been extensively used to transduce cells of the granule cell layer and study their inherent properties in an intact brain environment. In addition, lentivirus-based vectors have been used to deliver transgenes to replicative and non-replicative cells as well, such as post mitotic neurons of the CNS. However, only few studies have been dedicated to address the applicability of these widespread used vectors to hippocampal cells in vivo. Therefore, the aim of this study was to extensively characterize the cell types that are effectively transduced in vivo by VSVg-pseudotyped lentivirus-based vectors in the hippocampus dentate gyrus.     

A general test of the Copernican principle

To date, there has been no general way of determining if the Copernican principle--that we live at a typical position in the Universe--is in fact a valid assumption, significantly weakening the foundations of cosmology as a scientific endeavor. Here we present an observational test for the Copernican assumption which can be automatically implemented while we search for dark energy in the coming decade. Our test is entirely independent of any model for dark energy or theory of gravity and thereby represents a model-independent test of the Copernican principle.     

Analysis of transverse momentum and event shape invN scattering

The transverse momentum distributions of hadrons produced in neutrino-nucleon charged current interactions and their dependence onW are analysed in detail. It is found that the components of the transverse momentum in the event plane and normal to it increase withW at about the same rate throughout the availableW range. A comparison withe ⁺ e ^? data is made. Studies of the energy flow and angular distributions in the events classified as planar do not show clear evidence for high energy, wide angle gluon radiation, in contrast to the conclusion of a previous analysis of similar neutrino data.     

Coherent production of π+ mesons in ν-neon interactions

The coherent production of π⁺ mesons by charged current neutrino interactions on neon nuclei in BEBC is compared to the predictions of the PCAC hypothesis and the meson dominance model. Good agreement is observed.     

Highly luminescent, triple- and quadruple-stranded, dinuclear Eu, Nd, and Sm(III) lanthanide complexes based on bis-diketonate ligands

The bis(beta-diketone) ligands 1,3-bis(3-phenyl-3-oxopropanoyl)benzene, H(2)L(1) and 1,3-bis(3-phenyl-3-oxopropanoyl) 5-ethoxy-benzene, H(2)L(2), have been prepared for the examination of dinuclear lanthanide complex formation and investigation of their properties as sensitizers for lanthanide luminescence. The ligands bear two conjugated diketonate binding sites linked by a 1,3-phenylene spacer. The ligands bind to lanthanide(III) or yttrium(III) ions to form neutral homodimetallic triple stranded complexes [M(2)L(1)(3)] where M = Eu, Nd, Sm, Y, Gd and [M(2)L(2)(3)], where M = Eu, Nd or anionic quadruple-stranded dinuclear lanthanide units, [Eu(2)L(1)(4)](2-). The crystal structure of the free ligand H(2)L(1) has been determined and shows a twisted arrangement of the two binding sites around the 1,3-phenylene spacer. The dinuclear complexes have been isolated and fully characterized. Detailed NMR investigations of the complexes confirm the formation of a single complex species, with high symmetry; the complexes show clear proton patterns with chemical shifts of a wide range due to the lanthanide paramagnetism. Addition of Pirkle's reagent to solutions of the complexes leads to splitting of the peaks, confirming the chiral nature of the complexes. Electrospray and MALDI mass spectrometry have been used to identify complex formulation and characteristic isotope patterns for the different lanthanide complexes have been obtained. The complexes have high molar absorption coefficients (around 13 x 10(4) M(-1)cm(-1)) and display strong visible (red or pink) or NIR luminescence upon irradiation at the ligand band around 350 nm, depending on the choice of the lanthanide. Emission quantum yield experiments have been performed and the luminescence signals of the dinuclear complexes have been found to be up to 11 times more intense than the luminescence signals of the mononuclear analogues. The emission quantum yields and the luminescence lifetimes are determined to be 5% and 220 micros for [Eu(2)L(1)(3)], 0.16% and 13 micros for [Sm(2)L(1)(3)], and 0.6% and 1.5 micros for [Nd(2)L(1)(3)]. The energy level of the ligand triplet state was determined from the 77 K spectrum of [Gd(2)L(1)(3)]. The bis-diketonate ligand is shown to be an efficient sensitizer, particularly for Sm and Nd. Photophysical studies of the europium complexes at room temperature and 77 K show the presence of a thermally activated deactivation pathway, which we attribute to ligand-to-metal charge transfer (LMCT). Quenching of the luminescence from this level seems to be operational for the Eu(III) complex but not for complexes of Sm(III) and Nd(III), which exhibit long lifetimes. The quadruple-stranded europium complex has been isolated and characterized as the piperidinium salt of [Eu(2)L(1)(4)](2-). Compared with the triple-stranded Eu(III) complex in the solid state, the quadruple-stranded complex displays a more intense emission signal with a distinct emission pattern indicating the higher symmetry of the quadruple-stranded complex.     

Improvements to EPA method 531.1 for the analysis of carbamates that resulted in the development of U.S. EPA Method 531.2

This project is undertaken to fully optimize the U.S. Environmental Protection Agency Method 531.1 post-column chemistries and to incorporate recent advances in liquid chromatographic separation, post-column derivatization, and detection techniques. Sample preservation and storage stability studies establish citric acid as a suitable replacement for the caustic monochloroacetic acid in the current method and confirm its antimicrobial effectiveness. Performance of an alternate set of commercially available post-column reagents is also investigated. This research has resulted in the publication of Method 531.2, a high-performance liquid chromatographic direct injection method for the analysis of N-methylcarbamoyloximes and N-methylcarbamates using post-column derivatization and fluorescence detection.