Zirconium(IV) fluorosulphates : Preparation and characterization

Zr(SO₃F)₄, (A); ZrO(SO₃F)₂, (B); Zr(O₂CCH₃)₂, (SO₃F)₂, (C); and Zr(O₂CCH₃)₃SO₃F, (D) have been prepared and characterized (elemental analysis,i.r. Spectra and thermal analysis). The SO₃F groups are bidentate in (A) – (C) but have C_3V symmetry in D where all the three oxygen atoms of SO₃F group are coordinated in an equivalent manner. (A) – (D) are good Lewis acids and form coordination complexes with pyridine, triphenylphosphine oxide and 2,2′-bipyridyl. The thermal decomposition of the fluorosulphates is complex.     

Peptides—XXXVII: Synthesis of the 1–37 fragment of a lysozyme analogue

Combination of the protected peptide fragments 1–16, 17–26 and 27–37 to yield the 1–37 portion of a lysozyme analogue is described. The fragments were combined using DCCI with the addition of HONSu, and the products purified mainly by gel filtration.     

Complexes of divalent oxovanadium,manganese, iron,cobalt, nickel and copper with the ligand derived from the reaction of 2-aminopyridine and acetylacetone

Summary 2-Aminopyridine reacts with acetylacetone in the presence of VO^II, Mn^II, Fe^II, Co^II, Ni^II, and Cu^II metal salts to give complexes of the type [VO(Ap₂ac)₂X]X and [M(Ap₂ac)₂X₂] where (Ap₂ac) is the ligand formedin situ. The complexes are characterised as distorted octahedral by analyses, conductance, molecular weight, magnetic, electronic and i.r. spectral studies. The i.r. studies reveal that two molecules of aminopyridine are joined by a molecule of acetylacetone through a three carbon atom bridge and that the ligand coordinates through the azomethine and imino nitrogen atoms, whereas pyridine does not take part in coordination. The electronic spectra have been interpreted and tentative assignments are made. In the far i.r. spectra, various metal ligand vibrations are observed and discussed. Attempts to carry out electrophilic substitutions in the complexes failed.     

The integration of certain products of the multivariableH-function with a general class of polynomials

The authors present six general integral formulas (four definite integrals and two contour inegrals) for theH-function of several complex variables, which was introduced and studied in a series of earlier papers by H. M. Srivastava and R. Panda (cf., e.g., [25] through [29]; see also [14] through [18], [20], [24], [32], [34], [35], [37], and [38]). Each of these integral formulas involves a product of the multivariableH-function and a general class of polynomials with essentially arbitrary coefficients which were considered elsewhere by H. M. Srivastava [21]. By assigning suiatble special values to these coefficients, the main results (contained in Theorems 1, 2 and 3 below) can be reduced to integrals involving the classical orthogonal polynomials including, for example, Hermite, Jacobi [and, of course, Gegenbauer (or ultraspherical), Legendre, and Tchebycheff], and Laguerre polynomials, the Bessel polynomials considered by H. L. Krall and O. Frink [9], and such other classes of generalized hypergeometric polynomials as those studied earlier by F. Brafman [3] and by H. W. Gould and A. T. Hopper [8]. On the other hand, the multivariableH-functions occurring in each of our main results can be reduced, under various special cases, to such simpler functions as the generalized Lauricella hypergeometric functions of several complex variables [due to H. M. Srivastava and M. C. Daoust (cf. [22] and [23])] which indeed include a great many of the useful functions (or the products of several such functions) of hypergeometric type (in one and more variables) as their particular cases (see,e. g., [1], [10] and [39]). Many of the aforementioned applications of our integral formulas (contained in Theorems 1, 2 and 3 below) are considered briefly. Further usefulness of some of these consequences of Theorems 1 and 2 in terms of the classical orthogonal polynomials is illustrated by considering a simple problem involving the orthogonal expansion of the multivariableH-function in series of Jacobi polynomials. It is also shown how these general integrals are related to a number of results scattered in the literature. 0261 0262 V     

4-(Arylaminothiocarbonyl)-1-(1-o-methoxyphenylcarbamido)-ethylpiperazines as anticonvulsants

Several 4-(arylaminothiocarbonyl)-1-(1-o-methoxyphenylcarbamido)-ethylpiperazines were synthesized and evaluated for their anticonvulsant activity against pentylenetetrazol-induced seizures in mice. The ability of substituted piperazines to inhibit in vitro respiratory activity of rat brain homogenates was also determined to study their structure-activity relationship.     

Interaction of chloroform with aniline, o-toluidine and N,N-dimethyl aniline

Heats of mixing aniline, o-toluidine, and N,N-dimethyl aniline with chloroform have been determined by an adiabatic calorimeter. The results have been examined for molecular interactions between them, and they indicate that aniline and o-toluidine are associated through hydrogen bonds. Enthalpy of bond formation in a 1:1 complex has also been determined.     

Organic solid-state reactions

The role of voids and cracks in solid-state reaction between 8-hydroxyquinoline and phthalic anhydride has been investigated. 8-hydroxyquinoline reacts with phthalic anhydride both in solution and in solid state, forming a 1:1 yellow-colored complex. X-ray diffraction studies prove that the complex obtained from the solid-state reaction is the same as that obtained from solution. Several techniques have been used to study the kinetics of the reaction in the solid state. Kinetic studies by capillary technique showed that surface migration is the mode of diffusion of reactant concerned. Dilatometric technique confirms the formation of cracks and voids in the systems and shows that the reaction is propagated through the channels.     

Syntheses of the first N-mono- and N,N'-dipolyfluoroalkyl-4,4'-bipyridinium compounds

Reactions of 4,4'-bipyridine (1) with excess of polyfluoroalkyl iodides (2a-d) at 100-110 degrees C, under neat conditions, led to the formation of monoquaternary salts (3a-d) in > 90% yields. Salts 3a-d were metathesized with LiN(SO2CF3)2 either in water or water/acetone mixtures to form ionic liquids (4a-d), respectively, in > 88% yields. When 1 was reacted with 2.5 equivalent of 2a-c in DMF at 110 degrees C, the diquaternary salts 5a-c were formed in > 85% yields. Alternatively, 5a-c were also synthesized by heating a mixture of 3a-c and 2a-c (1.25 equivalent) in DMF. The metathesis reaction of 5a-c with LiN(SO2CF3)2 produced dicationic ionic liquids (6a-c) in > 86% yield.     

Vinyl polymerization: Kinetics of Ce(IV)–acetophenone-initiated polymerization of acrylonitrile in acetic–sulfuric acid mixtures

The polymerization of acrylonitrile (M) initiated by the Ce(IV)–acetophenone (AP) redox pair has been studied in acetic–sulfuric acid mixtures in a nitrogen atmosphere. The rate of polymerization is proportional to [M]^3/2, [AP]^1/2 and [Ce(IV)]^1/2. The rate of disappearance of ceric ion,–R_Ce, is proportional to [AP], [M], and [Ce(IV)]. The effect of certain salts, solvent, acid and temperature on both the rates have been investigated. A suitable kinetic scheme has been proposed, and the composite rate constants k_p ²(k/k/_t) and k₀/k_i are reported.