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911.
We consider a general class of models consisting of a small quantum system $S$ interacting with a reservoir $R$ . We compare three applications of 2nd order perturbation theory (the Fermi Golden Rule) to the study of such models: (1) the van Hove (weak coupling) limit for the dynamics reduced to $S$ ; (2) the Fermi Golden Rule applied to the Liouvillean—an argument that was used in recent papers on the return to equilibrium; (3) the Fermi Golden Rule applied to the so-called C-Liouvillean. These three applications lead to three Level Shift Operators. As our main result, we prove that if the reservoir $R$ is thermal (if it satisfies the KMS condition), then the Level Shift Operator obtained in (1) (often called the Davies generator) and the Level Shift Operator constructed in (2) are connected by a similarity transformation. We also show that the Davies generator coincides with the Level Shift Operator obtained in (3) for a general $R$ . 相似文献
912.
Jensen TW Hu BH Delatore SM Garcia AS Messersmith PB Miller WM 《Journal of the American Chemical Society》2004,126(46):15223-15230
The ability to present cell adhesion molecule (CAM) ligands in controlled amounts on a culture surface would greatly facilitate the control of cell growth and differentiation. Supported lipid monolayer/bilayer systems have previously been developed that allow for presentation of CAM ligands for cell interaction; however, these systems have employed peptide loadings much higher than those used in poly(ethylene glycol) (PEG)-based immobilization systems. We report the development of synthetic methods that can be used for the efficient and versatile creation of many linear and cyclic lipid-linked peptide moieties. Using RGD-based peptides for the alpha5beta1 integrin as a model system, we have demonstrated that these lipopeptides support efficient cell binding and spreading at CAM ligand loadings as low as 0.1 mol %, which is well below that previously reported for supported lipid systems. Engineered lipopeptide-based surfaces offer unique presentation options not possible with other immobilization systems, and the high activity at low loadings we have shown here may be extremely useful in presenting multiple CAM ligands for studying cell growth, differentiation, and signaling. 相似文献
913.
Coronado E Galán-Mascarós JR Gómez-García CJ Murcia-Martínez A Canadell E 《Inorganic chemistry》2004,43(25):8072-8077
The salt [ET](3)[Sb(2)(L-tart)(2)].CH(3)CN (1) has been obtained by electrocrystallization of the organic donor bis(ethylendithio)tetrathiafulvalene (ET or BEDT-TTF) in the presence of the chiral anionic complex [Sb(2)(L-tart)(2)](2-) (L-tart = (2R,3R)-(+)-tartrate). This salt crystallizes in the chiral space group P2(1)2(1)2(1) (a = 11.145(2) angstroms, b = 12.848(2) angstroms, c = 40.159(14) angstroms, V = 5750.4(14) angstroms(3), Z = 4) and is formed by alternating layers of the anions and of the organic radicals in a noncentrosymmetric alpha-type packing. This compound shows a room temperature electrical conductivity of approximately 1 S.cm(-1) and semiconducting behavior with an activation energy of approximately 85 meV. Analysis of the magnetic susceptibility and band structure, however, suggests that this compound should be a narrow band gap semiconductor. 相似文献
914.
García Ruano JL Alonso de Diego SA Martín MR Torrente E Martín Castro AM 《Organic letters》2004,6(26):4945-4948
[reaction: see text] Thermolysis of enantiopure sulfonyl pyrazolines 4 and 5, easily obtained from (Z)-3-p-tolylsulfinylacrylonitriles (1), afforded sulfonyl cyclopropanes (6, 7) in a completely stereoselective manner in almost quantitative yields. Both cyclopropanes and alkylidenecyclopropanes, containing one or two chiral carbon atoms, one of them being quaternary, were obtained by hydrogenolysis of the C-S bonding and under the conditions reported by Julia, respectively. The highly stereoselective extrusion of nitrogen suggests a concerted mechanism. 相似文献
915.
The present study aims to investigate the quercetin-deoxyribonucleic acid (DNA) interaction occurring in bulk solution either electrochemically using differential pulse voltammetry or spectrophotometrically, in order to explain the possible DNA-damaging activity of quercetin. A very weak interaction between quercetin and DNA in solution was found to take place. However, since extensive quercetin-induced DNA damage via reaction with Cu(II) has been reported, an electrochemical study of the DNA-Cu(II)-quercetin system in solution was undertaken. The product of DNA interaction with quercetin-Cu(II) complex was observed. Damages to DNA were electrochemically recognized via the increasing of the anodic peaks corresponding to the oxidation of guanosine and adenosine bases and spectrophotometrically via increasing of the 260 nm adsorption band. It was also observed that dsDNA damage produced by the quercetin-Cu(II) complex occurred with time. Control experiments with different mixtures of Cu(II), quercetin, ssDNA, dsDNA or poly[A] were carried out in order to establish a possible mechanism of interaction between DNA and quercetin via Cu(II). 相似文献
916.
Rodríguez Flores J Berzas Nevado JJ Contento Salcedo AM Cabello Díaz MP 《Journal of separation science》2004,27(1-2):33-40
A capillary zone electrophoresis method is proposed for the separation of six of the antidepressants most used for the treatment of mental illness (clomipramine, paroxetine, fluoxetine, citalopram, fluvoxamine, and trazodone). Optimum conditions for their separation were investigated. A background electrolyte solution consisting of 50 mM phosphate buffer adjusted to pH 2.0, hydrodynamic injection, and 25 kV as separation voltage were used. Relative standard deviations (RSD) were <0.38% and <2.93% for migration time and corrected peak area (n = 24), respectively. Detection limits obtained for the six antidepressants ranged from 0.03 to 0.11 mg L(-1). Stability of the solutions, linear concentration range, accuracy, and precision were examined during validation of the method. A ruggedness test of this method was performed using the fractional factorial model of Plackett-Burman, requiring in our case design of a matrix of 15 experiments, in which the influence of seven factors at three different levels was tested on different electrophoretic results: efficiency; resolution; and corrected peak area. Statistical evaluation of electrophoretic results was achieved by Youden and Steiner's method. The described method is rapid, sensitive, and rugged and it was tested for the pharmaceutical formulation analysis, giving recoveries between 95.6 and 99.1% with respect to the nominal content. 相似文献
917.
Steven Dale Cutkosky Jü rgen Herzog Ana Reguera 《Transactions of the American Mathematical Society》2004,356(5):1833-1874
Let be a resolution of singularities of a normal surface singularity , with integral exceptional divisors . We consider the Poincaré series
where
We show that if has characteristic zero and is a semi-abelian variety, then the Poincaré series is rational. However, we give examples to show that this series can be irrational if either of these conditions fails.
where
We show that if has characteristic zero and is a semi-abelian variety, then the Poincaré series is rational. However, we give examples to show that this series can be irrational if either of these conditions fails.
918.
Recent progress in somatic embryogenesis from selected mature trees of Quercus suber, has led to a demand for maintenance of a large number of selected embryogenic lines. To facilitate the management of this material a protocol for the long-term storage of this germplasm should be defined. This study reports on the use of a simple vitrification procedure for the successful cryopreservation of three cork oak embryogenic lines. High embryo recovery levels (88-93 percent) were obtained by first preculturing 2-4 mg clumps of two or three globular embryos on semisolid medium containing 0.3 M sucrose for three days, followed by incubation in PVS2 vitrification solution at 0 degree C for 60 min before direct immersion in liquid nitrogen. The mean number of embryos produced per explant was significantly greater for cryostored embryos than for untreated stock cultures, but the productivity of the latter was recovered in subsequent subcultures of the material produced by cryostored embryos. The germination and plant regeneration rates achieved by cultures derived from cryostored embryos, around 60 percent, were similar to those of non-cryopreserved stock cultures. 相似文献
919.
We show that with the help of the two well known Einstein assumptions used by him in the treatment of geometry on relativistically rotating disc, and elementary logical analysis only, two different and opposite models of rotating discs can be constructed: In one of them the disc, set rotating from the stationary state, changes neither its radius nor circumference, as measured from stationary inertial frame; while in the other both the radius and the circumference contract by the same Lorentz factor. We also show that one can construct discs whose contraction factors vary continuously from unity (no contraction) to the full Lorentz factor. 相似文献
920.