全文获取类型
收费全文 | 323篇 |
免费 | 14篇 |
国内免费 | 3篇 |
专业分类
化学 | 198篇 |
晶体学 | 2篇 |
力学 | 14篇 |
综合类 | 1篇 |
数学 | 47篇 |
物理学 | 78篇 |
出版年
2023年 | 6篇 |
2022年 | 9篇 |
2021年 | 12篇 |
2020年 | 9篇 |
2019年 | 9篇 |
2018年 | 4篇 |
2017年 | 14篇 |
2016年 | 19篇 |
2015年 | 12篇 |
2014年 | 10篇 |
2013年 | 38篇 |
2012年 | 14篇 |
2011年 | 13篇 |
2010年 | 7篇 |
2009年 | 10篇 |
2008年 | 18篇 |
2007年 | 15篇 |
2006年 | 8篇 |
2005年 | 6篇 |
2004年 | 8篇 |
2003年 | 5篇 |
2002年 | 4篇 |
2001年 | 6篇 |
2000年 | 3篇 |
1999年 | 5篇 |
1998年 | 5篇 |
1995年 | 9篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 3篇 |
1990年 | 5篇 |
1989年 | 4篇 |
1988年 | 3篇 |
1987年 | 3篇 |
1986年 | 6篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1981年 | 5篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1968年 | 2篇 |
1967年 | 2篇 |
1965年 | 1篇 |
1960年 | 1篇 |
排序方式: 共有340条查询结果,搜索用时 15 毫秒
331.
Despite the significant influence of solution temperature on the structure of electrical double layer, the lack of theoretical model intercepts us to explain and predict the interesting experimental observations. In this work, we study the structure of electrical double layer as a function of thermochemical properties of the solution by proposing a phenomenological temperature dependent surface complexation model. We found that by introducing a buffer layer between the diffuse layer and stern layer, one can explain the sensitivity of zeta potential to temperature for different bulk ion concentrations. Calculation of the electrical conductance as function of thermochemical properties of solution reveals the electrical conductance not only is a function of bulk ion concentration and channel height but also the solution temperature. The present work model can provide deep understanding of micro- and nanofluidic devices functionality at different temperatures. 相似文献
332.
333.
A. M. Al-Sabagh N. G. Kandile Nahed Amer Omaima Ramadan E. A. Khamis 《Journal of Dispersion Science and Technology》2013,34(9):1307-1320
Ten new quaternary ammonium salts (QASs) were designed and synthesized from hydrolyzed fatty oils; the hydrolyzed oils were used as a source of alkyl halides to prepare the QASs by refluxing the fatty alkyl halide with ethoxylated amines as untraditional 3° amines in acetone. The structure of the prepared QASs were characterized by FTIR and 1H NMR spectroscopy. The prepared cationic surfactants QASs were tested as corrosion inhibitors for carbon steel in 1 M HCl solution. The corrosion inhibition efficiency was measured using weight loss and potentiodynamic polarization methods. The inhibition efficiencies obtained from the two employed methods are in good agreement with each other. In generally, the inhibition efficiency increased with increasing the inhibitor concentration. From the obtained data it was found that the inhibition efficiency of QASs, which, based on ethoxylated aromatic tertiary amine, is greater than the efficiencies of the QASs based on ethoxylated aliphatic tertiary amine. The QASs based on fatty alkyl halide from palm oil exhibited the best inhibition efficiency than QASs based on fatty alkyl halides from coconut oil. The potentiodynamic polarization measurements indicated that the inhibitors are of mixed type. The adsorption of the inhibitors on the carbon steel surface in the acid solution was found to obey Langmuir's adsorption isotherm. The free energy of adsorption processes was calculated and discussed. The surface active properties were calculated on the basic of surface tension measurements. The obtained data of inhibition efficiencies were discussed on the light of surface active properties of these QASs and their chemical structures. The quantum chemical calculations was proceeded for QHL1,4,5 and QHP3,4,5 the following quantum chemical indices such as the bond length, bond angle, charge density distribution, highest occupied molecular orbital (HOMO), the lowest unoccupied molecular orbital (LUMO), energy gap ΔE?HOMO –LUMO, and dipole moment (u) were considered.The surface morphology of carbon steel sample was investigated by scanning electron microscopy. 相似文献
334.
A. A. Amer O. A. Omran A. Khodairy 《Phosphorus, sulfur, and silicon and the related elements》2013,188(7):1653-1664
Hydrazinopiperidinomethanethione 2 was prepared and reacted with active halo compounds, carbon disulfide, phenyliso-thiocyanate, ylidenenitriles, and N,S-acetyls to give thiadiazine 4–7 , thiadiazole 8–10 , and pyrazole 11,13 , 14–17 derivatives, respectively. 相似文献
335.
Flame photometric detection in the sulfur channel has been evaluated for sulfur speciation and quantification in comprehensive two-dimensional gas chromatography [GC × GC-FPD(S)] for S-compound speciation in shale extracts. Signal non-linearity and potential quenching effects were reportedly major limitations of this detector for analysis of sulfur in complex matrices. However, reliable linear relationships with correlation coefficient >0.99 can be obtained if the sum of the square root of each modulation slice in GC × GC is plotted vs. sulfur concentration. Furthermore, the quenching effects are reduced due to essentially complete separation of S-containing components from the hydrocarbon matrix. An increase of S/N of up to 150 times has been recorded for benzothiophene and dibenzothiophene in GC × GC-FPD when compared to GC-FPD due to the modulation process. As a consequence, 10 times lower detection limits were observed in the former mode. The applicability of the method was demonstrated using shale oil sample extracts. Three sulfur classes were completely separated and the target class (thiophenes) was successfully quantified after the rest of the sample was diverted to the second detector by using a heart-cut strategy. Based on the proposed method, 70% of the sulfur in the shale oil was assigned to the thiophenes, 24% to benzothiophenes, and 5% to dibenzothiophene compounds. 相似文献
336.
Aromatic diamine monomers, including m-phenylenediamine (mPD), 2-methyl-m-phenylenediamine (2Me-mPD), 4-methyl-m-phenylenediamine (4Me-mPD) and trimethyl-m-phenylenediamine (tMe-mPD), were polymerized by chemical oxidation using ammonium persulfate as an oxidant. Aluminium triflate (Al(OTf)3) was also used for the first time as a co-catalyst under various polymerization conditions. The polymerization yield was improved when Al(OTf)3 was introduced to the polymerization reaction for most polymers. The poly(2-methyl-m-phenylenediamine) (P(2Me-mPD)), poly(4-methyl-m-phenylenediamine) (P(4Me-mPD)) and poly(trimethyl-m-phenylenediamine) (P(tMe-mPD)) polymers exhibited better solubility than poly(m-phenylenediamine) (P(mPD)) polymers in most common solvents. The homopolymers obtained were characterized by FT-IR, 1H and 13C NMR, WAXD and TGA. The results showed that the yield, solubility and structure of the polymers are significantly dependent on the polymerization conditions. TGA measurements indicated that the polymers have good thermal stability and decompose above 400 °C in nitrogen. 相似文献
337.
Amer Al Abdel Hamid Carl P. Tripp Alice E. Bruce Mitchell R. M. Bruce 《Research on Chemical Intermediates》2011,37(7):791-810
In order to gain additional insight into mercury selectivity with nano-sized DMSA-[silica], we investigated a series of ligands related to DMSA, these are: monomercaptosuccinic acid; MMSA, 2-mercapto-4-methyl-5-thiazoleacetic acid; MCT, ortho-thiosalicylic acid; o-TSA and para-thiosalicylic acid; p-TSA. The MMSA chelate is structurally similar to DMSA except that it has only one thiol group. The chelates o-TSA and p-TSA each have one thiol and one carboxylic acid group. MCT includes neutral S and N atoms in close proximity to the thiolate binding site. MCT, o-TSA and p-TSA resemble each other in having equal numbers of carboxylic acid and thiol groups and formation of amide bonds with the linker on silica is expected to eliminate the carboxylate binding sites, making thiolates the only binding sites for Hg(II), Cd(II), and Pb(II) metals ions in the nano-sized; MMSA-[silica], MCT-[silica], o-TSA-[silica], and p-TSA-[silica]. Each of the nano-sized MMSA-[silica], MCT-[silica], o-TSA-[silica], and p-TSA-[silica], show a higher preference for Hg(II) over Cd(II) and Pb(II) compared to the same free chelates in solution, respectively. In addition, there are differences in the level of metal ion chelation for each functionalized silica nanoparticle. These differences in the degree of metal chelation for each functionalized silica nanoparticles surface are explained by the difference in thiolate/carboxylate ratio upon attachment to the surface and on steric reasons based on the orientation of the thiol groups on the surface. When attached via amide bond formation, the thiolate site in o-TSA-[silica] will face towards the silica surface, while for p-TSA-[silica], the thiolate site is expected to be pointed outwards and away from the silica surface. In comparing MMSA-[silica] to DMSA-[silica], the thiolate/carboxylate ratio decreases from 2/1 in DMSA-[silica] to 1/1 in MMSA-[silica] (assuming attachment via one amide bond in each case). This effect of increasing the ratio of thiolate to carboxylate upon attachment to the surface is believed to play a role in the selectivity enhancement towards Hg(II) over Cd(II) and Pb(II). 相似文献
338.
To elucidate the reasons underlying the poor penetration of non-viral vectors in tissues, relating transport properties to
physico-chemical parameters of vectors may be crucial. These properties can be influenced by the presence of multiples labels
that are used. Therefore utilizing a vector with minimum of labels preferably not more than one is important to studying penetration
in tissues. The cell impermeant bisintercalating dye YOYO-1 was found suitable to both monitor the formation of complexes
between DNA and an amphipathic peptide LK15 and, to track their penetration in HCT116 spheroids by confocal microscopy. The
results revealed a limited decrease of fluorescence ascribed to the high affinity of YOYO-1 to bind DNA. The residual fluorescence
of complexes can be exploited to monitor penetration into spheroids, after correction for YOYO-1 attenuation, and to revealing
hyaluronidase-induced reduced binding. Hence high affinity dyes such as YOYO-1 with inefficiently quenched fluorescence may
be important to establish a relation between novel medicines characteristics and penetration in tissues. 相似文献
339.
Vibration of structures is often an undesirable phenomena and should be avoided or controlled. There are two techniques to
control the vibration of a system, that is, active and passive control techniques. In this paper, a negative feedback velocity
is applied to a dynamical system, which is represented by two coupled second order nonlinear differential equations having
both quadratic and cubic nonlinearties. The system describes the vibration of an aircraft tail. The system is subjected to
multi-external excitation forces. The method of multiple time scale perturbation is applied to solve the nonlinear differential
equations and obtain approximate solutions up to third order of accuracy. The stability of the system is investigated applying
frequency response equations. The effects of the different parameters are studied numerically. Various resonance cases are
investigated. A comparison is made with the available published work.
The English text was polished by Keren Wang. 相似文献
340.
Md Rifat Hasan Ahad Amer Alsaiari Burhan Zain Fakhurji Mohammad Habibur Rahman Molla Amer H. Asseri Md Afsar Ahmed Sumon Moon Nyeo Park Foysal Ahammad Bonglee Kim 《Molecules (Basel, Switzerland)》2022,27(13)
The conventional drug discovery approach is an expensive and time-consuming process, but its limitations have been overcome with the help of mathematical modeling and computational drug design approaches. Previously, finding a small molecular candidate as a drug against a disease was very costly and required a long time to screen a compound against a specific target. The development of novel targets and small molecular candidates against different diseases including emerging and reemerging diseases remains a major concern and necessitates the development of novel therapeutic targets as well as drug candidates as early as possible. In this regard, computational and mathematical modeling approaches for drug development are advantageous due to their fastest predictive ability and cost-effectiveness features. Computer-aided drug design (CADD) techniques utilize different computer programs as well as mathematics formulas to comprehend the interaction of a target and drugs. Traditional methods to determine small-molecule candidates as a drug have several limitations, but CADD utilizes novel methods that require little time and accurately predict a compound against a specific disease with minimal cost. Therefore, this review aims to provide a brief insight into the mathematical modeling and computational approaches for identifying a novel target and small molecular candidates for curing a specific disease. The comprehensive review mainly focuses on biological target prediction, structure-based and ligand-based drug design methods, molecular docking, virtual screening, pharmacophore modeling, quantitative structure–activity relationship (QSAR) models, molecular dynamics simulation, and MM-GBSA/MM-PBSA approaches along with valuable database resources and tools for identifying novel targets and therapeutics against a disease. This review will help researchers in a way that may open the road for the development of effective drugs and preventative measures against a disease in the future as early as possible. 相似文献