Dimorphamides A – C,New Polyphenolic Amides from Atriplex dimorphostagia

Dimorphamides A–C ( 1 – 3 , resp.), three new polyphenolic amides, have been isolated from the BuOH‐soluble fraction of the whole plant of Atriplex dimorphostagia, along with two known compounds, thymidine and N‐[(E)‐feruloyl]tyramine. Their structures have been determined on the basis of spectral studies.     

Facile radical mediated synthesis of azetidin-2,3-diones: potential synthons for biologically active compounds

Abstract  

An operationally simple and efficient approach for the synthesis of azetidin-2,3-diones is described. The starting substrate 2-(2-bromobenzyloxy)ethanoyl chloride was treated with appropriate Schiff’s bases in triethylamine and dichloromethane to afford 3-(2-bromobenzyloxy)azetidin-2-ones. The synthesis of azetidin-2,3-diones was successfully achieved via radical mediated rearrangement of appropriately substituted 3-(2-bromobenzyloxy)azetidin-2-ones using n-tributyltin hydride and AIBN in refluxing dry benzene.     

Reflected Generalized Backward Doubly SDEs Driven by Lévy Processes and Applications

In this paper, we study reflected generalized backward doubly stochastic differential equations driven by Teugels martingales associated with Lévy process (RGBDSDELs in short) with one continuous barrier. Under uniformly Lipschitz coefficients, we prove an existence and uniqueness result by means of the penalization method and the fixed-point theorem. As an application, this study allows us to give a probabilistic representation for the solutions to a class of reflected stochastic partial differential integral equations (SPDIEs in short) with a nonlinear Neumann boundary condition.     

Development of a multianalyte method for the determination of anabolic hormones in bovine urine by isotope-dilution GC–MS/MS

A sensitive, specific and selective multianalyte GC–MS/MS method has been developed for the determination of 11 anabolic hormones in bovine urine. After adjusting the urine pH to 4.8, the samples were spiked with deuterated internal standards and submitted to enzymatic hydrolysis with β-glucuronidase/arylsulfatase. Hormones were eluted with methanol through a C18 solid phase cartridge and submitted to a liquid–liquid extraction. Analytes were derivatized by adding N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) with 1% trimethylchlorosilane and GC–MS data were obtained in the positive electron impact tandem mass mode. Under these conditions, no matrix effects were observed and limit of detection values were in the range of 0.005 ng/mL (diethylstilbestrol) to 0.38 ng/mL (17α-methyltestosterone and 17α-ethynylestradiol). Recoveries from 81% (α-zeranol) to 149% (17α-methyltestosterone) were found under the selected conditions. These results were better than those found using heptafluorobutyric anhydride (HFBA) as derivative reagent and those measured in full scan and selective ion monitoring modes.     

Structural and biochemical analyses reveal how ornithine acetyl transferase binds acidic and basic amino acid substrates

Structural and biochemical analyses reveal how ornithine acetyl-transferases catalyse the reversible transfer of an acetyl-group from a basic (ornithine) to an acidic (glutamate) amino acid by employing a common mechanism involving an acetyl-enzyme intermediate but using different side chain binding modes.     

Radiation effects on the MHD flow near the stagnation point of a stretching sheet: revisited

This paper considers the effects of radiation on the flow near the two-dimensional stagnation point of a stretching sheet immersed in a viscous and incompressible electrically conducting fluid in the presence of an applied constant magnetic field. The external velocity and the stretching velocity of the sheet are assumed to vary linearly with the distance from the stagnation point. The governing partial differential equations are transformed into a system of ordinary differential equations using a similarity transformation, before being solved numerically by the Keller-box method. The features of the heat transfer characteristics for different values of the governing parameters are analyzed and discussed. The results indicate that the heat transfer rate at the surface decreases in the presence of radiation.     

Radiation effects on the MHD flow near the stagnation point of a stretching sheet: revisited

This paper considers the effects of radiation on the flow near the two-dimensional stagnation point of a stretching sheet immersed in a viscous and incompressible electrically conducting fluid in the presence of an applied constant magnetic field. The external velocity and the stretching velocity of the sheet are assumed to vary linearly with the distance from the stagnation point. The governing partial differential equations are transformed into a system of ordinary differential equations using a similarity transformation, before being solved numerically by the Keller-box method. The features of the heat transfer characteristics for different values of the governing parameters are analyzed and discussed. The results indicate that the heat transfer rate at the surface decreases in the presence of radiation.