Analysis of urinary nucleosides. III. Identification of 5'-deoxycytidine in urine of a patient with head and neck cancer

Modified nucleosides in the urine have been postulated to be diagnostic indices of disease, particularly of cancer. The urine of a patient with terminal head and neck cancer has been found to contain a modified nucleoside with a protonated molecule of m/z 228. By means of high-performance liquid chromatography/ion trap mass spectrometry (HPLC/ITMS) and capillary liquid chromatography/triple quadruple mass spectrometry (CapLC/TQMS) we have identified the compound as 5'-deoxycytidine. This is the first report of 5'-deoxycytidine in man: in addition to the elucidation of its structure, its possible origins and the potential significance of its occurrence are discussed.     

Crystal structure of tris (phenylammonium) chloride pentachloroantimonate (III) monohydrate

The tris (phenylammonium) chloride pentachloroantimonate (III) monohydrate salt is triclinic with the following cell parameters: a = 9.4283(3), b = 11.4482(3), c = 13.1748(3)Å, = 113.493(2), = 90.381(2), = 97.331(1)°, V = 1290.86(6)ų, with Z = 2 formula units. The structure consists of [C₆H₅NH₃]⁺ cations, water molecules, Cl^– anions, and SbCl₅ square pyramids. Hydrogen bonds, established through water molecule, link the anions [SbCl₅]^2– and Cl^– and make an infinite chain in the [011] direction. Chains are linked together via another hydrogen bond network originating from the ammonium groups. A distortion of the SbCl₅ square pyramid can be attributed to the stereo activity of the Sb(III) lone electron pair.     

Crystal structure of a new double salt hydrate SrCd2Cl6⋅8H2O

SrCd₂Cl₆8H₂O crystallizes in the space group and has the unit cell dimensions a = 9.688(2) Å, b = 11.212(2) Å, c = 7.732(3) Å, = 99.85(21)°, = 89.95(22)°, = 75.81(13)°, and Z = 2. After refinement through full-matrix least-squares methods, the reliability factor R in the final cycle is 4.65%. A very persistent occurrence of twinning by pseudosymmetry was observed. The twin element is a twofold axis [001]. The title compound exhibits five endothermic peaks, which have been detected by differential scanning calorimetry and interpreted from thermogravimetry.     

Crystal structure of di(N-benzyl piperidinium) pentachloroantimonate(III) dihydrate

The salt di(N-benzyl piperidinium) pentachloroantimonate(III) dihydrate crystallizes in the orthorhombic system with space group Cmc2₁, the unit cell dimensions are: a = 29.383(1), b = 10.509(2), c = 9.941(1) Å, with Z = 8. The structure shows a layer arrangement perpendicular to the a axis: planes of SbCl₆ octahedra alternate with planes of [C₁₂H₁₇N]⁺ cations. The SbCl₆ octahedra are connected through a O(W)–HCl hydrogen bonds and a chlorine bridge, so that infinite unidimensional chains of composition [SbCl₅(H₂O)₂]^2n– _n are formed in the structure along the c direction. These chains are connected to [C₁₂H₁₇N]⁺ entities by N–HCl and N–HO(W) hydrogen bonds, forming a three-dimensional network. It was found that lengths of Sb–Cl bonds may differ from each other. The differences shown as a distortion of the SbCl₆ octahedra were attributed to the Sb(III) lone electron pair stereoactivity.     

On theorems of Beurling and Cowling-Price for certain nilpotent Lie groups

Let G be a connected simply connected nilpotent Lie group. In [A. Baklouti, N. Ben Salah, The Lp−Lq version of Hardy's Theorem on nilpotent Lie groups, Forum Math. 18 (2006) 245-262], we proved for 2?p,q?+∞ the Lp−Lq version of Hardy's Theorem known as the Cowling-Price Theorem. In the setup where 1?p,q?+∞, the problem is still unsolved and the upshot is known only for few cases. We prove in this paper such a result in the context of 2-NPC nilpotent Lie groups. A proof of the analogue of Beurling's Theorem is also provided in the same context.     

Thermoluminescence and photoluminescence of LiNaSO4:Eu irradiated with 24 and 48 MeV Li ion beam

Thermoluminescence (TL) of LiNaSO₄:Eu phosphor, irradiated with 24 and 48 MeV ⁷Li ions at different fluences in the range 5×10⁹-1×10¹² ion/cm², has been studied. The samples from the same batch were also exposed to γ-rays from a Cs¹³⁷ source for comparative studies. The TL glow curves of the materials, irradiated with ⁷Li ions, have similar structures to that of γ-irradiated sample. They have a simple structure with a prominent peak at 412 K along with small one at around 481 K. The intensity ratios of 412-481 K peaks have been observed to increase with fluence increasing, while that of γ-irradiated sample shows a reverse trend. This could be attributed to the changes in the recombination center populations due to ⁷Li ions, that have been implanted inside the matrix of LiNaSO₄:Eu, during irradiation and might also act as a source for new trapping and luminescent centers. The implantation has been confirmed by TRIM calculations. The penetration depths (where the ion comes to rest) are found to be 145 and 463 μm corresponding to 24 and 48 MeV ion beam energies, respectively, which are less than the thickness of the sample chips (∼800 μm). The efficiencies of LiNaSO₄:Eu to 24 and 48 MeV ⁷Li ions measured relative to γ-rays of Cs¹³⁷ are found to be 0.007 and 0.024, respectively. Theoretical analysis of the glow curves of the samples irradiated by ⁷Li ions and γ-rays were done by glow curve deconvolution method to determine trapping parameters of various peaks. The experimentally observed linearity/sublinearity has been discussed in the frame of track interaction model. Photoluminescence studies in the ⁷Li ions irradiated and un-irradiated samples show that europium ions have incorporated in the host in their divalent (emission at 440 nm) as well as trivalent (emissions at 594, 615 and 700 nm) forms. The intensities of the emission bands of these ions have been observed to increase with fluence increasing.     

An application of the decomposition method for the generalized KdV and RLW equations

We consider solitary-wave solutions of the generalized regularized long-wave (RLW) and Korteweg-de Vries (KdV) equations. We prove the convergence of Adomian decomposition method applied to the generalized RLW and KdV equations. Then we obtain the exact solitary-wave solutions and numerical solutions of the generalized RLW and KdV equations for the initial conditions. The numerical solutions are compared with the known analytical solutions. Their remarkable accuracy are finally demonstrated for the generalized RLW and KdV equations.     

Coordination compounds of hydrazine derivatives with transition metals. Part 22. Reaction of aroylhydrazones with copper(II) salts

Summary Two different crystalline forms namely the greenanti and the brownsyn were isolated from the reaction of copper(II) acetate with some aldehydic aroylhydrazones, while others gave only the brown form. With copper(II) chloride, however, reduction of copper(II) ions occurred and copper(I) chelates of general formula Cu(HL)Cl were obtained. Tridentate ligands such as salicylaldehyde and pyridine-2-carbaldehyde aroylhydrazones gave copper(II) chelates Cu(L)Cl₂. A tentative reduction mechanism involving intramolecular electron transfer was proposed. In such a mechanism the steric requirements of the aroylhydrazone molecule and the presence of a third coordination site would stabilize the dipositive oxidation state of copper.     

Selective microdetermination of phosphate based on Volhard's titration

A selective method for the microdetermination of phosphate has been developed. The phosphate is precipitated from homogeneous solutions as silver phosphate, which after being filtered and washed is dissolved in dilute nitric acid, and the silver ions set free are determined by Volhard's titration. Whereas the halide ions interfere if the conventional precipitation is adopted, they do not interfere if precipitation is conducted from homogeneous solutions. The method is simple and accurate to a maximum error of ±1%.