A model for universal spatial variations of temperature fluctuations in turbulent Rayleigh-Bénard convection

We propose a theoretical model for spatial variations of the temperature variance σ~2( z, r)( z is the distance from the sample bottom and r the radial coordinate) in turbulent Rayleigh-Bénard convection(RBC).Adapting the "attached-eddy" model of shear flow to the plumes of RBC, we derived an equation for σ~2 which is based on the universal scaling of the normalized RBC temperature spectra. This equation includes both logarithmic and power-law dependences on z/λ_(th), where λ_(th) is the thermal boundary layer thickness. The equation parameters depend on r and the Prandtl number Pr, but have only an extremely weak dependence on the Rayleigh number Ra Thus our model provides a near-universal equation for the temperature variance profile in turbulent RBC.     

Concise Total Synthesis of Enigmazole A

An efficient entry into the phosphorylated marine macrolide enigmazole A is described. Enigmazole A interferes with c‐Kit signaling by an as yet unknown mode of action and is therefore a potential lead in the quest for novel anticancer agents. Key to success is a gold‐catalyzed cascade comprising a [3,3]‐sigmatropic rearrangement of a propargyl acetate along the periphery of a macrocyclic scaffold, followed by a transannular hydroalkoxylation of the resulting transient allenyl acetate. This transformation mandated the use of a chiral gold catalyst to ensure a matching double‐asymmetric setting. Other noteworthy steps are the preparation of the oxazole building block by a palladium‐catalyzed C?H activation, as well as the smooth ring‐closing alkyne metathesis of a diyne substrate bearing a propargylic leaving group, which has only little precedent.     

Starke erleichterung der carbonylolefinierung mit organoschwermetall-reagenzien durch eine diphenylphosphorylgruppe im reagenz

Carbonyl olefination with a lithiomethane, having besides the group P(O)Ph₂ at the methane C-atom an organo-heavy-metal group, occurs at low temperatures to give exclusively diphenylphosphoryl substituted olefins.