全文获取类型
收费全文 | 2177篇 |
免费 | 34篇 |
国内免费 | 9篇 |
专业分类
化学 | 1195篇 |
晶体学 | 4篇 |
力学 | 70篇 |
数学 | 272篇 |
物理学 | 679篇 |
出版年
2021年 | 12篇 |
2019年 | 16篇 |
2018年 | 15篇 |
2017年 | 11篇 |
2016年 | 31篇 |
2015年 | 22篇 |
2014年 | 34篇 |
2013年 | 87篇 |
2012年 | 84篇 |
2011年 | 108篇 |
2010年 | 70篇 |
2009年 | 48篇 |
2008年 | 131篇 |
2007年 | 127篇 |
2006年 | 99篇 |
2005年 | 94篇 |
2004年 | 90篇 |
2003年 | 63篇 |
2002年 | 78篇 |
2001年 | 52篇 |
2000年 | 56篇 |
1999年 | 23篇 |
1998年 | 24篇 |
1997年 | 24篇 |
1996年 | 51篇 |
1995年 | 63篇 |
1994年 | 42篇 |
1993年 | 50篇 |
1992年 | 41篇 |
1991年 | 27篇 |
1990年 | 24篇 |
1989年 | 23篇 |
1988年 | 26篇 |
1987年 | 28篇 |
1986年 | 17篇 |
1985年 | 20篇 |
1984年 | 24篇 |
1983年 | 20篇 |
1982年 | 21篇 |
1981年 | 32篇 |
1980年 | 22篇 |
1979年 | 23篇 |
1978年 | 25篇 |
1977年 | 23篇 |
1976年 | 29篇 |
1975年 | 25篇 |
1974年 | 17篇 |
1973年 | 21篇 |
1971年 | 14篇 |
1970年 | 12篇 |
排序方式: 共有2220条查询结果,搜索用时 9 毫秒
941.
942.
943.
The mechanism of ketocarboxylic acid formation in the base treatment of bicyclo[2.2.1]heptyl halolactones has been determined. On the basis of stoichiometry, kinetics, effect of leaving group, and isotopic labeling experiments, a dehydrohalogenation mechanism is proposed in which cleavage of the carbon-halogen bond precedes that of the carbon-hydrogen bond in the transition state. The relationship between El-like and syn-E2 transition states in these systems is discussed.In the bicyclo[2.2.2]octyl series base treatment of the halolactones yields oxidocarboxylic acids. The difference in behavior between the two systems is rationalized on the basis of molecular geometry. 相似文献
944.
Infrared spectra of NaNO2 and KNO2 in the region of the anion internal modes have been obtained using a diamond anvil cell at pressures up to 65 kbar. At 39°C NaNO2 undergoes a phase transition at ca. 10.0 kbar, not at 14 kbar as reported from an earlier IR study. A similar transition was found at 6.3 kbar for KNO2. The symmetric modes lose intensity with increasing pressure, and all modes suffer blue-shifts. For KNO2 ν(NO)5 shifts much more than ν(NO)a. 相似文献
945.
McLain JL Poterya V Molek CD Jackson DM Babcock LM Adams NG 《The journal of physical chemistry. A》2005,109(23):5119-5123
A technique has been developed to simultaneously determine recombination rate coefficients, alpha e, and initial concentrations of ion types that coexist in a flowing afterglow plasma. This was tested using the H3(+) + allene reaction in which two different C3H3+ isomers are produced. Use of an electrostatic Langmuir probe enabled the C3H3+ isomer branching ratios for propargyl and cyclic C3H3+ from this allene reaction and their alpha e to be determined over the temperature range 172-489 K. The study showed that the cyclic C3H3+ to propargyl C3H3+ branching ratios from the allene reaction varied from 50/50 at 172 K to 18/82 at 489 K. Over this temperature range, the alpha e for both isomers change only slightly. The room temperature alpha e values for propargyl and cyclic C3H3+ are (1.15 +/- 0.2) x 10(-7) and (8.00 +/- 0.1) x 10(-7) cm3/s, respectively. The data are discussed relative to current theories and in relation to fuel-rich flame chemistry, interstellar molecular synthesis, and modeling of Titan's atmosphere. 相似文献
946.
Rao FV Houston DR Boot RG Aerts JM Hodkinson M Adams DJ Shiomi K Omura S van Aalten DM 《Chemistry & biology》2005,12(1):65-76
Family 18 chitinases play key roles in organisms ranging from bacteria to man. There is a need for specific, potent inhibitors to probe the function of these chitinases in different organisms. Such molecules could also provide leads for the development of chemotherapeuticals with fungicidal, insecticidal, or anti-inflammatory potential. Recently, two natural product peptides, argifin and argadin, have been characterized, which structurally mimic chitinase-chitooligosaccharide interactions and inhibit a bacterial chitinase in the nM-mM range. Here, we show that these inhibitors also act on human and Aspergillus fumigatus chitinases. The structures of these enzymes in complex with argifin and argadin, together with mutagenesis, fluorescence, and enzymology, reveal that subtle changes in the binding site dramatically affect affinity and selectivity. The data show that it may be possible to develop specific chitinase inhibitors based on the argifin/argadin scaffolds. 相似文献
947.
The first synthesis of a conjugated trihydroxy eicosatetraenoic acid, a possible structure for Lipoxin A is described. A biomimetic approach was utilized. 相似文献
948.
Adams Tidjani Yasushi Watanabe 《Journal of polymer science. Part A, Polymer chemistry》1995,33(9):1455-1460
γ-Oxidation of linear low-density polyethylene based on hexene and butene was investigated. Irradiation was performed at different dose rates in air (from 2 rad/s to 100 rad/s). Degraded samples were analyzed with IR combined with NO and SF4 derivatizations. Our results showed that the lower the dose rate, the higher the degree of oxidation in terms of γ-product formation. Ketone species appeared to be the dominant γ-products. The G values of γ-product formation were very dependent on the dose rate of initiation. Comparison of the G value ratio of different γ-products revealed stoechiometry differences. The complex appearance and disappearance of unsaturations was tentatively explained. The modifications of elongation at break induced by γ-irradiation were monitored by molecular changes in weight. This was not conclusive because changes in elongation at break are inconsistent with changes in Mw/Mn. © 1995 John Wiley & Sons, Inc. 相似文献
949.
A time independent diagrammatic technique based on the Wick theorem and graphical methods of spin algebras, as outlined in Part I, is applied to a simple open shell case having one unpaired electron in addition to the pure singlet closed shell. Compact explicit expressions for the matrix elements of a spin independent Hamiltonian between conveniently chosen spin symmetry adapted states are given for the ground, mono- and bi-excited configurations. 相似文献
950.
Spivey AC Colley J Sprigens L Hancock SM Cameron DS Chigboh KI Veitch G Frampton CS Adams H 《Organic & biomolecular chemistry》2005,3(10):1942-1952
The syntheses of three decalin-based tert-thiols displaying varying degrees of solubility in aqueous milieu are described. The S-nitroso derivatives of these compounds have also been prepared and the structures of two of these determined by single crystal X-ray diffraction. These compounds have been designed for studying the interaction of nitric oxide (NO) with thiols under physiological conditions. 相似文献