A method for the analysis of hot-film anemometer signals in two-phase flows

The authors discuss the application of hot-film anemometers in gas-liquid two-phase flow. Having stored the digitized record of the anemometer output signal on magnetic tape, methods are discussed that permit the identification of the vapour-phase using electronic computer programs. Methods are described to identify large vapour slugs and small bubbles. The authors propose an extension of these methods to the treatment of two-phase flows containing both large and small bubbles.     

Chemical speciation of radionuclides migrating in groundwaters

In order to more accurately predict the rates and mechanisms of radionuclide migration from lowlevel waste disposal facilities via groundwater transport, ongoing studies are being conducted at field sites at Chalk River Laboratories to identify and characterize the chemical speciation of mobile, long-lived radionuclides migrating in groundwaters. Large-volume water sampling techniques are being utilized to separate and concentrate radionuclides into particulate, cationic, anionic, and nonionic chemical forms. Most radionuclides are migrating as soluble, anionic species which appear to be predominately organoradionuclide complexes. Laboratory studies utilizing anion exchange chromatography have separated several anionically complexed radionuclides, e.g.,⁶⁰Co and¹⁰⁶Ru, into a number of specific compounds or groups of compounds. Large-volume ultra-filtration experiments have shown that significant fractions of the radionuclides are being transported in these groundwaters in the form of macromolecules having molecular weights ranging from less than 3,000 to 100,000.     

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A note on a problem arising from risk theory

In this note we give an answer to a problem of Gheorghiţă Zbăganu that arose from the study of the properties of the moments of the iterates of the integrated tail operator.     

Molecular dynamics of cis‐1‐(2‐hydroxy‐5‐ methylphenyl)ethanone oxime and N‐(2‐hydroxy‐4‐methylphenyl)acetamide in solution studied by NMR spectroscopy

The formation of hydrogen bonds and molecular dynamics for the molecules cis‐1‐(2‐hydroxy‐5‐methylphenyl)ethanone oxime ( I ) and N‐(2‐hydroxy‐4‐methylphenyl)acetamide ( II ) have been investigated in solution using NMR. The results confirm the formation of O? H···O, O? H···N and O···H? N type inter‐ and intramolecular hydrogen bonds. Spin‐lattice relaxation times (T₁), activation energy of molecular dynamics and energy of intramolecular hydrogen bonds have been determined. Copyright © 2010 John Wiley & Sons, Ltd.     

Lateralization based on interaural phase differences: effects of frequency, amplitude, duration, and shape of rise/decay

Experiments in lateralization were performed to evaluate the relative contribution of envelope and phase cues in binaural hearing with particular reference to the effects of frequency, amplitude, shape of rise/decay, and duration of peak amplitude. Pure-tone signals were presented with interaural phase shifts ranging between 90 degrees and 360 degrees. For a given value of phase shift, the leading signal was presented randomly to the right or left ear over a block of 100 trials, and the laterality of the resultant image was judged. Rise/decay time was varied from 5 to 200 ms across blocks. The results confirmed our previous finding that a rise/decay time of at least 200 ms is required to secure a psychophysically steady-state signal. This value will, however, depend on the values chosen for the other signal parameters. Within limits, decreasing intensity could be compensated for by decreasing rise/decay, suggesting the psychophysical importance of the initial segment of the signal (precedence effect). For low frequencies of 650 to 1250 Hz, performance is sensitive to interaural phase shift and largely independent of frequency. For higher frequencies of 1500 and 2000 Hz, lateralization is independent of the phase cue and also largely insensitive to change in rise/decay time. Finally, performance remains unchanged with variation in peak duration ranging from 25 to 200 ms.     

A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water

The basis for the altered DNA specificities of two Cre recombinase variants, obtained by mutation and selection, was revealed by their cocrystal structures. The proteins share similar substitutions but differ in their preferences for the natural LoxP substrate and an engineered substrate that is inactive with wild-type Cre, LoxM7. One variant preferentially recombines LoxM7 and contacts the substituted bases through a hydrated network of novel interlocking protein-DNA contacts. The other variant recognizes both LoxP and LoxM7 utilizing the same DNA backbone contact but different base contacts, facilitated by an unexpected DNA shift. Assisted by water, novel interaction networks can arise from few protein substitutions, suggesting how new DNA binding specificities might evolve. The contributions of macromolecular plasticity and water networks in specific DNA recognition observed here present a challenge for predictive schemes.