全文获取类型
收费全文 | 216篇 |
免费 | 7篇 |
国内免费 | 2篇 |
专业分类
化学 | 115篇 |
晶体学 | 6篇 |
力学 | 15篇 |
数学 | 60篇 |
物理学 | 29篇 |
出版年
2023年 | 6篇 |
2022年 | 8篇 |
2021年 | 6篇 |
2020年 | 6篇 |
2019年 | 7篇 |
2018年 | 7篇 |
2017年 | 9篇 |
2016年 | 12篇 |
2015年 | 4篇 |
2014年 | 3篇 |
2013年 | 18篇 |
2012年 | 19篇 |
2011年 | 18篇 |
2010年 | 10篇 |
2009年 | 8篇 |
2008年 | 5篇 |
2007年 | 11篇 |
2006年 | 13篇 |
2005年 | 2篇 |
2004年 | 7篇 |
2003年 | 6篇 |
2002年 | 9篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1999年 | 2篇 |
1998年 | 4篇 |
1997年 | 2篇 |
1996年 | 4篇 |
1994年 | 2篇 |
1993年 | 5篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1983年 | 1篇 |
1981年 | 1篇 |
1975年 | 1篇 |
1970年 | 1篇 |
排序方式: 共有225条查询结果,搜索用时 15 毫秒
121.
Rodríguez de Castro Antonio Agnaou Mehrez Ahmadi-Sénichault Azita Omari Abdelaziz 《Transport in Porous Media》2019,130(3):799-818
Transport in Porous Media - With X-ray computed tomography still being flawed as a result of limitations in terms of spatial resolution and cost, toxic mercury intrusion porosimetry (MIP) is... 相似文献
122.
Brahim Ait Addi Abdelaziz Ait Addi Abdul Shaban El-Habib Ait Addi Mohamed Hamdani 《Electroanalysis》2021,33(2):400-411
The inhibition efficiency of H2PO42− ions against tin corrosion in 0.2 M maleic acid is studied using electrochemical methods, surface analytical methods, and thermodynamic analysis. The potentiodynamic polarization plots showed the presence of an active/passive transition state of the tin electrode. The EIS measurements confirmed that the inhibition efficiency of H2PO42− increased by increasing the concentration (η=81 % at Cinh=2.10−2 M) and decreased by rising the temperature. The polarization tests demonstrated that the inhibitor performs as a cathodic-type. The adsorption of the inhibitor was spontaneous and followed the Langmuir adsorption isotherm. A model of the inhibition mechanism was suggested. 相似文献
123.
124.
Farid A. Badria Abdelaziz E. Abdelaziz Amira H. Hassan Abdullah A. Elgazar Eman A. Mazyed 《Molecules (Basel, Switzerland)》2020,25(23)
Curcumin is a natural compound that has many medical applications. However, its low solubility and poor stability could impede its clinical applications. The present study aimed to formulate dry proniosomes to overcome these pitfalls and improve the therapeutic efficacy of Curcumin. Curcumin-loaded proniosomes were fabricated by the slurry method according to 32 factorial design using Design-Expert software to demonstrate the impact of different independent variables on entrapment efficiency (EE%) and % drug released after 12 h (Q12h). The optimized formula (F5) was selected according to the desirability criteria. F5 exhibited good flowability and appeared, after reconstitution, as spherical nanovesicles with EE% of 89.94 ± 2.31% and Q12h of 70.89 ± 1.62%. F5 demonstrated higher stability and a significant enhancement of Q12h than the corresponding niosomes. The docking study investigated the ability of Curcumin to bind effectively with the active site of DNA polymerase of Herpes simplex virus (HSV). The antiviral activity and the safety of F5 were significantly higher than Curcumin. F5 improved the safety of Acyclovir (ACV) and reduced its effective dose that produced a 100% reduction of viral plaques. Proniosomes could be promising stable carriers of Curcumin to be used as a safe and efficient antiviral agent. 相似文献
125.
Mackaya Terence Emery Ahmadi-Senichault Azita Omari Abdelaziz Rodríguez de Castro Antonio 《Transport in Porous Media》2021,136(2):587-605
Transport in Porous Media - The aim of the present work is to investigate the flow rate/pressure gradient relationship for the flow of yield stress fluids through rectilinear capillaries of... 相似文献
126.
127.
The reaction of cyanoacetylhydrazine with chloroacetyl chloride gave N'-(2-chloroacetyl)-2-cyanoacetohydrazide. The latter underwent cyclization to afford 1-(5 amino-3-hydroxy-1H-pyrazol-1-yl)-2-chloroethanone, which underwent nucleophilic substitution to give 3-(5-amino-3-hydroxy-1H-pyrazol-1-yl)-3-oxopropanenitrile. The latter two compounds were used as key synthons to synthesize new thiophene, pyran, thiazole and some fused heterocyclic derivatives. The antitumor activity of the newly synthesized compounds was evaluated against three human tumor cells lines, namely breast adenocarcinoma (MCF-7), non-small cell lung cancer (NCI-H460) and CNS cancer (SF-268) and some of these compounds were found to exhibit much higher inhibitory effects towards the three tumor cell lines than the Gram positive control doxorubicin. 相似文献
128.
129.
El Bouzidi L Larhsini M Markouk M Abbad A Hassani L Bekkouche K 《Natural product communications》2011,6(10):1447-1450
In the present study, we report for the first time the antioxidant and antimicrobial activities of Withania frutescens (L.) Pauquy roots and leaves. Total phenolic content was determined using the Folin-Ciocalteu method and antioxidant activity was evaluated by the DPPH free radical scavenging and reducing power methods. Antimicrobial activity tests were carried out against ten bacterial species involved in nosocomial infections and two opportunistic clinical yeast isolates. The ethyl acetate and n-butanol leaf fractions exhibited the highest DPPH radical scavenging activity with IC50 = 4.53 +/- 0.12 and 8.49 +/- 0.46 microg/mL, respectively. The n-butanol root fraction showed the greatest reducing power comparable with that of quercetin at 0.4 mg/mL. The dichloromethane leaf fraction exhibited the highest antibacterial activity against both Gram-positive and Gram-negative bacteria with MIC values ranging between 50 and 400 microg/mL, depending on the tested bacteria. However, none of the examined extracts exhibited anticandidal activity. The polyphenol and glycowithanolide constituents appeared to be responsible for the antioxidant capacity of W. frutescens, whereas the observed antimicrobial activity may be due to the presence of withanolides. 相似文献
130.
El Maatougui A Crespo A Silva AM Coelho A 《Combinatorial chemistry & high throughput screening》2011,14(7):570-582
An efficient solution-phase parallel procedure to perform the structural diversification of some formyl-nitrogen heterocycles (A) using the reusable TBD supported base is described. The library synthesis is based in a consecutive Alkylation-Knoevenagel functionalisation that uses alkyl halides (B), Michael acceptors (C) and activated methylene compounds (D) as diversity elements. 相似文献