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氟苯尼考在南美白对虾体内药物代谢及残留消除规律 总被引:2,自引:0,他引:2
研究了南美白对虾口服氟苯尼考药饵给药后,在血液、肌肉中的残留及消除规律,采用Agilengt 1100型液相色谱仪测定组织中药物含量.口服给药后血液中氟苯尼考浓度在1 h立即达到峰值,药物开始向肌肉组织中运转,血药浓度在1 h后下降,而肌肉中浓度达到峰值;此后无论血液还是肌肉中氟苯尼考浓度均缓慢下降,到10d后血液中的氟苯尼考不能检出.口服氟苯尼考后,在南美白对虾体内吸收快,血药浓度高;药物在肌肉中消除缓慢,维持时间长. 相似文献
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Flexoelectric effect, referring to the strain gradient induced polarization, widely exists in dielectric materials, but its molecular dynamics has not been studied so much so far. In this work, the radial distribution function of BaTiO3 and the phase transition temperatures have been investigated, and the results show that the core-shell potential model is effective and the structure of BaTiO3 is stable in a temperature range of 10 K-150 K. Molecular dynamics simulated hysteresis loops of BaTiO3 show that anisotropy can play an important role in the coercive field. Based on the rational simulation process, the effects of cantilever beam bent angle and fixed length on the polarization are analyzed. It is found that the small bent angle of the curved cantilever beam can give a proportional relationship with a fixed end length and a non-linear relationship is presented when the bent angle is much larger. The prediction of flexoelectric coefficient in BaTiO3 is 18.5 nC/m. This work provides a computational framework for the study of flexoelectric effect by using molecular dynamics. 相似文献