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31.
At present, the existing scaffold materials cannot well meet the high strength and toughness requirements for the repairing of typical stressed tissues. And the commercial software for 3D printing scaffold modeling and mechanical performance simulation is complex to operate and has poor interoperability with 3D printers. In order to solve these problems, a silk fibroin (SF) based bio-ink was prepared for tough scaffold, and a software was developed for compression performance simulation of 3D printing scaffold based on SF and finite element analysis strategy. The printability of the bio-ink and the mechanical properties of the corresponding hydrogels and 3D printing scaffolds were characterized. The cell compatibility of the related scaffolds was evaluated by using fibroblasts and living/dead staining kit. Based on the SF based bio-ink, scaffolds with different heights and porosities were designed and printed. By using the developed software and the universal testing machine, the compression performance of related scaffolds was simulated and tested separately, and further compared with each other. Results show that the SF based bio-ink has good printability. And the 3D printing scaffold prepared by this ink presents high strength and toughness (modulus of elasticity: (1.86 ± 0.28)MPa, modulus of compression: (1.95 ± 0.11)MPa, elongation at break: (114.03 ± 14.40)%, compression strain ≥ 70%). In addition, the scaffold has good cell compatibility (L929 cell viability≥92.4%), which is expected to be used for the repair and regeneration of stressed tissues. The software is easy to operate, and can be used not only for the modeling of 3D printing scaffolds, but also for accurately predicting their compressive mechanical properties. In addition, the model data can also be directly imported into the 3D printer to guide the efficient preparation of the corresponding 3D printing scaffolds. This research is expected to provide important guidance for the rapid design and fabrication of tissue specific 3D printing scaffolds with bionic structure and mechanical properties. © Eco-Vector, 2023. All rights reserved. 相似文献
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基于新型量子点荧光微球的氯霉素免疫层析试纸条的制备和应用 总被引:1,自引:0,他引:1
以羧基化CdTe/ZnSe量子点荧光微球为标记物,通过1-乙基-(3-二甲基氨基丙基)碳二亚胺/N-羟基琥珀酰亚胺(EDC/NHS)活化法将氯霉素(CAP)单克隆抗体与量子点荧光微球偶联制备荧光探针.氯霉素全抗原(CAP-HS-BSA)及羊抗鼠二抗分别喷涂硝酸纤维素膜,形成检测线(T线)和质控线(C线),组装成新型氯霉素量子点荧光微球免疫层析试纸条,建立了快速、定量检测牛奶中CAP的方法.本研究开发的量子点荧光微球试纸条可在15 min内完成牛奶样品中CAP的定量检测,线性范围为0.1~100.0μg/L,检出限为0.1μg/L.牛奶样品CAP的加标回收率为93.3%~97.9%,相对标准偏差在4.9%~6.9%之间. 相似文献
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利用合成矩阵的概念和翻转矩阵的技巧,结合矩阵的次转置、次自共轭,中心对称等相关情况给出合成矩阵的几个性质,并获得关于n阶翻转矩阵的第n-1个合成矩阵的表达式. 相似文献
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<正>受生物膜离子通道结构和功能的启发,人工制备固体纳米孔道门控开关器件一直备受关注[1,2].基于仿生纳米孔道的非对称离子传输性质制备的离子二极管和场效应管装置对于构建离子电路和能量转换的纳米器件至关重要[3,4].然而,仿生制备的固体纳米孔道在离子传输过程中有漏电流的存在,严重影响了固体纳米孔道应用的灵敏度和信噪比[5].针对这一问题,研究者利用DNA分子的特殊识别和自组装的功能特性,相继构筑了基于DNA和纳米孔道的智能响应体系[6,7].但在之前的研究工作中,分[8] 相似文献
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Hexagonal boron phosphide and boron arsenide van der Waals heterostructure as high-efficiency solar cell 下载免费PDF全文
The rapid development of two-dimensional (2D) materials offers new opportunities for 2D ultra-thin excitonic solar cells (XSCs). The construction of van der Waals heterostructure (vdWH) is a recognised and effective method of integrating the properties of single-layer 2D materials, creating particularly superior performance. Here, the prospects of h-BP/h-BAs vdW heterostructures in 2D excitonic solar cells are assessed. We systematically investigate the electronic properties and optical properties of heterogeneous structures by using the density functional theory (DFT) and first-principles calculations. The results indicate that the heterogeneous structure has good optoelectronic properties, such as a suitable direct bandgap and excellent optical absorption properties. The calculation of the phonon spectrum also confirms the well-defined kinetic stability of the heterstructure. We design the heterogeneous structure as a model for solar cells, and calculate its solar cell power conversion efficiency which reaches up to 16.51% and is higher than the highest efficiency reported in organic solar cells (11.7%). Our work illustrates the potential of h-BP/h-BAs heterostructure as a candidate for high-efficiency 2D excitonic solar cells. 相似文献
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卫星三轴姿态确定系统的光纤陀螺/星敏感器组合技术研究 总被引:8,自引:0,他引:8
为了满足卫星三轴姿态确定的精度要求,提出了基于状态估计法的星敏感器和光纤陀螺组合的方案,并设计了相应姿态确定算法。通过仿真证明:此方案能达到高精度卫星姿态确定系统的要求。 相似文献