Phase-sensitive fat suppression steady-state free procession sequence with phase correction

Robust and fast fat suppression is a challenge in balanced steady-state free precession （SSFP） magnetic resonance imaging. Although single-acquisition phase-sensitive SSFP can provide fat-suppressed images in short scan time, phase errors, especially spatially-dependent phase shift, caused by a variety of factors may result in misplacement of fat and water voxels. In this paper, a novel phase correction algorithm was used to calibrate those phase errors during image reconstruction. This algorithm corrects phase by region growing, employing both the magnitude and the phase information of image pixels. Phantom and in vivo imagings were performed to validate the technique. As a result, excellent fat-suppressed images were acquired by using single-acquisition phase-sensitive SSFP with phase correction.     

超高场磁共振人体成像应用研究和医学前景

20世纪90年代初,随着第一代超高场磁共振成像仪的投入使用,因其诸多的优点,如更高的检测信噪比、更好的对比度、更强的BOLD效应和更宽的波谱,超高场磁共振成像成为国际医学磁共振领域最热门的研究方向之一.该文以最新一代的7.0 T MRI成像仪为例,简述超高场磁共振人体成像仪的系统结构、研究进展,并展望其在神经科学、认知科学和医学的应用前景.     

基于聚亚甲基蓝-碳纳米管复合膜固载血红蛋白的H2O2生物传感器

采用吸附和电化学聚合修饰方法,制得了聚亚甲基蓝-碳纳米管聚合膜玻碳电极(PMB-MWNTs/GCE),再将血红蛋白(Hb)固定在PMB-MwNTs/GCE表面,制备了稳定的Hb/PMB-MwNTs//GCE的H2O2生物传感器,并用循环伏安法对修饰电极的生物电催化行为进行了表征.研究结果表明,固定在PMB-MWNTs/...     

药学本科药物化学设计性实验类型及教学方法探讨

阐述了药学本科药物化学设计性实验 3种类型的选择 ,并以微波促进褪黑激素的合成为例进行了讨论 ,取得了较好的结果     

Interleaving Gradient Magnetic Field Method for Diffusion Weighted Spectroscopy

Diffusion-weighted magnetic resonance spectroscopy （DWS） has considerable potential in clinical and research applications. However, it is seldom implemented in conventional magnetic resonance imaging （MRI） scanners due to the strict hardware requirements. We propose an interleaving gradient magnetic field （IGMF） method based on point resolved spectroscopy （PRESS）. Four interlaced powerful diffusion sensitive gradient magnetic fields are positioned around the two π refocusing rf pulses in the PRESS sequence. This method utilizes the interval time in the PRESS pulse sequence, doubles the duration time of the diffusion sensitive gradient magnetic field and decreases the detrimental effect of the induced eddy current. The results of theoretical analysis and experimental observation demonstrate that the IGMF method is suitable for conventional MRI scanners.     

康托洛维奇-里茨杂交法及其应用

本文将Kantorovich法与Ritz法进行适当组合,吸收了二者的主要优点,提出了康托洛维奇法的一种改进方法.以二维问题为例,Kantorovich法在一个方向(例如y方向)的分布完全预先选定,这含有很大的主观任意性,因而限制了近似解的精度,改进法则在y方向仿Ritz法改进为一个含有若干个自由参数的分布函数,由于增加了近似解的自由度,故可改善解的精度.对Kantorovich法的另一改进是在计算高阶近似解时,通过逐项求解待定函数避免了求解更高阶微分方程或含更多方程的方程组,减少了计算量,降低了计算难度.用改进法求解了固体力学里的矩形截面柱体扭转问题和四边固支矩形板的弯曲问题,通过算例充分说明了此方法的特点和优越性.     

电感耦合等离子体-原子发射光谱法测定稀土萃取液中的铝

采用草酸沉淀分离稀土,电感耦合等离子体-原子发射光谱法测定稀土萃取分离时各级槽体液中的铝含量,方法快速准确,回收率在98.2%—107.6%之间,满足稀土分离现场检测需要。     

粘弹性随机有限元

以近似不可压缩粘弹增量有限元和摄动法为基础,利用增量法处理遗传积分,应用参数摄动考虑随机性,采用局部平均方法对随机场进行离散,通过相关结构分解减少计算量,发展了一种粘弹性随机有限元方法.研究表明,尽管粘弹性材料本构关系具有时间相依性,其随机摄动格式并不存在"长期项"的影响.应用该方法进行粘弹性结构的随机模拟,程序实施简单,计算效率较高、精度较高.