Synthesis and characterization of n=5, 6 members of the La4Srn−4TinO3n+2 series with layered structure based upon perovskite

Layered compounds have been synthesized and structurally characterized for the n=5 and 6 members of the perovskite-related family La₄Sr_n−4Ti_nO_3n+2 by combining X-ray diffraction and transmission electron microscopy. Their structure can be regarded as comprising [(La,Sr)₅Ti₅O₁₇] and [(La,Sr)₆Ti₆O₂₀] perovskite blocks joined by crystallographic shears along the a-axis, with consecutive blocks shifted by 1/2 [100]_p. The n=5 member is similar to the previously reported n=5 member of other A_nB_nO_3n+2-related series. The n=6 member, which has only been briefly reported in other systems previously, is also a well-behaved member of this A_nB_nO_3n+2 series.     

Structure and stability of thiourea with water, DFT and MP2 calculations

The relative stabilities of thiourea in water are investigated computationally by considering thiourea–water complexes containing up to 1–6 water molecules (CS(NH₂)₂(H₂O)_n=1–6) using density functional theory and MP2 ab initio molecular orbital theory. The results show that the thiourea complex is stable and has an unusually high affinity for incoming water molecules. The clusters are progressively stabilized by the addition of water molecules, as indicated by the increasing of the binding energy. The binding energy of the cluster to each H₂O molecule is about 33 kJ mol⁻¹ for n=1–5.The C–S bond, N–C bond distance, Mulliken populations and binding energy keep approximately constant as the clusters increase in size with an increasing number of H₂O molecules. As the solvation progresses, the C–S distance increases monotonically while the Mulliken populations on the C–S bond reduces monotonically with the addition of each H₂O molecule, indicating that the C–S bond of the thiourea unit in the clusters is de-stabilized with an increasing number of H₂O molecules. Charge transfers for the clusters are mainly found at N, S atoms of the thiourea.     

Development of miniaturized multi-channel high-performance liquid chromatography for high-throughput analysis

We have developed miniaturized multi-channel high-performance liquid chromatography (HPLC) system. With this system, we can simultaneously separate multiple samples, using a single high-pressure gradient pump, a chip-based sample injection unit, a monolithic silica capillary column array, and a multi-channel UV detection unit based on fiber optics. The injection unit has a simplified structure composed of brass housing and a quartz microchip having microchannels and access ports, which enable a direct injection of sample to multi-channel by commercial multichannel micropipette. Moreover, that possesses a function of microvalve, and on-chip definition of sample injection plugs achieved with a cross channel injection method, providing each column of monolithic silica capillary array. The substances in channels were simultaneously detected with UV having multiple cells. Standard samples were analyzed for characterizing newly developed system, and sharp peaks were obtained with reproducibility data of < 0.9% (R.S.D.). Analysis of tryptic digestion of casein was also employed. These results show that the novel multi-channel HPLC system has the benefits for the high-throughput analysis in the post-genomic analysis/combinatorial chemistry.     

Infrared (1.2-1.6 microm) luminescence in Cr4+:Yb3Al5O12 single crystal with 940 nm diode pumping

Infrared (1.2-1.6 microm) luminescence in a ytterbium aluminium garnet (YbAG) crystal, doped with Cr (0.05at.%) ions, was investigated under CW laser diode pumping (lambda=940 nm). The Cr4+ emission band was observed with its peak at 1.34 microm and measured to be about 1.3 times with respect to Yb3+ IR luminescence (lambda=1.03 microm). We demonstrate that for the excitation wavelength of 940 nm Yb3+ ions act as sensitizers of the 3B2(3T2)-3B1(3A2) emission of Cr4+ ions. This crystal is promising as a high-efficient system for tunable laser (1.2-1.6 microm) output.     

Novel Cp2LnX-mediated coupling-cyclization of propargyl bromide: a new construction of the benzene ring skeleton

In the presence of Cp2LnX-HgCl2, the treatment of RC identical to CCH2Br with Mg leads to the formation of benzene derivatives C6H4R2-1,2 (R = H, Ph) in moderate yield, which provides a new method for the construction of the benzene ring skeleton.     

Highly efficient non-doped blue fluorescent OLEDs with low efficiency roll-off based on hybridized local and charge transfer excited state emitters

Designing a donor–acceptor (D–A) molecule with a hybridized local and charge transfer (HLCT) excited state is a very effective strategy for producing an organic light-emitting diode (OLED) with a high exciton utilization efficiency and external quantum efficiency. Herein, a novel twisting D–π–A fluorescent molecule (triphenylamine–anthracene–phenanthroimidazole; TPAAnPI) is designed and synthesized. The excited state properties of the TPAAnPI investigated through photophysical experiments and density functional theory (DFT) analysis reveal that its fluorescence is due to the HLCT excited state. The optimized non-doped blue OLED using TPAAnPI as a light-emitting layer exhibits a novel blue emission with an electroluminescence (EL) peak at 470 nm, corresponding to the Commission International de L''Eclairage (CIE) coordinates of (0.15, 0.22). A fabricated device termed Device II exhibits a maximum current efficiency of 18.09 cd A⁻¹, power efficiency of 12.35 lm W⁻¹, luminescence of ≈29 900 cd cm⁻², and external quantum efficiency (EQE) of 11.47%, corresponding to a high exciton utilization efficiency of 91%. Its EQE remains as high as 9.70% at a luminescence of 1000 cd m⁻² with a low efficiency roll-off of 15%. These results are among the best for HLCT blue-emitting materials involved in non-doped blue fluorescent OLEDs. The performance of Device II highlights a great industrial application potential for the TPAAnPI molecule.

A new pure fluorescent blue HLCT-emitter was designed and synthesized. Highly efficient non-doped blue OLEDs with low efficiency roll-off were achieved.     

不对称合成 ⅩⅥ.(十)-樟脑亚胺的立体控制反应和樟脑结构的研究——(十)-樟脑缩苄胺转动势能计算和构象分析

本文对N-(对-硝基)苄基-1,7,7-三甲基-双环[2.2.1]庚烷-2-亚胺(3)和N-[11—[12-羟基-12-二苯基]甲基]苄基-1,7,7-三甲基-双环[2.2.1]庚烷-2-亚胺(4)进行了X-射线晶体结构分析。采用MOPAC程序的MNDO方法对(+)-樟脑缩苄胺即N-苄基-1,7,7-三甲基-双环[2.2.1]庚烷-2-亚胺(2a)的内部转动势能进行了理论计算。结果表明,(+)-樟脑缩苄胺(2a)以反式(trans)构象形式存在,它在不对称反应中的立体选择性主要受樟脑环上方C10甲基的控制。     

Physico-chemical Characterization of Mo-Hβ Zeolite Catalysts

A series of Mo-impregnated Hβ samples, with MoO3 loading in Hβ zeolite in the mass fraction range of 0. 5%-6.0%, were studied by means of XRD and IR in order to characterize their structures. Mo/Hβ sampies‘ crystallinity almost linearly decreases with increasing the amount of MoO3 loaded, The IR spectra and XRD patterns suggest that the progressive destabilization of the Hβ zeolite structure is caused by increasing Mo loading in (MoO3 Hβ zeolite). During the calcination, Al2(MoO4)3 formed from the dealumination of Hβ zeolite, causes the substantially partial breakdown of the zeolite framework when the Mo loading in MoO3 Hβ is relatively high.     

Amperometric determination of ascorbic acid at a novel ‘self-doped’ polyaniline modified microelectrode

A ‘self-doped’ polyaniline modified microelectrode, prepared by cyclic potential sweep on a microdisk gold electrode from –0.2 to 0.85 V in 0.5 mol/L sulfuric acid containing aniline and o-aminobenzoic acid, has been developed. The copolymerized process and the resulting polymer characteristics were investigated in detail. This composite film indicated a good electrochemical activity in a wide pH range even in basic solution. Meanwhile, the redox couple exhibited an excellent electrocatalytic activity for the oxidation of ascorbic acid. The oxidation overpotential of ascorbic acid was decreased over 200 mV at this modified electrode compared with a bare gold one. Moreover, the effects of film thickness and pH on the catalytic efficiency were further studied. The dependence of catalytic currents on the concentration of ascorbic acid was linear in the range of 1.2 × 10^–5～ 2.4 × 10^–3 mol/L with a correlation coefficient of 0.996. Also, the determination of ascorbic acid in actual samples was evaluated and the results are satisfactory.     

α-Tetralone glycosides from the green walnut husks of Juglans mandshurica Maxim. and their cytotoxic activities

Abstract

Five new α-tetralone glycosides, juglanbiosides A-E (1–5), together with an α-tetralone derivative (15) and nine known 1,4-naphthoquinones (6–14) were isolated from the 95% EtOH extract of green walnut husks of Juglans mandshurica Maxim. Their structures were elucidated by comprehensive spectroscopic methods (¹H, ¹³C NMR, DEPT, HSQC, HMBC, CD, HR-ESI-MS). In vitro cytotoxicities of all the isolated compounds were evaluated against BGC-823, HCT-15 and K562 cancer cell lines.