全文获取类型
收费全文 | 5050篇 |
免费 | 841篇 |
国内免费 | 1112篇 |
专业分类
化学 | 4199篇 |
晶体学 | 59篇 |
力学 | 332篇 |
综合类 | 99篇 |
数学 | 546篇 |
物理学 | 1768篇 |
出版年
2024年 | 18篇 |
2023年 | 90篇 |
2022年 | 170篇 |
2021年 | 204篇 |
2020年 | 195篇 |
2019年 | 222篇 |
2018年 | 170篇 |
2017年 | 179篇 |
2016年 | 248篇 |
2015年 | 263篇 |
2014年 | 280篇 |
2013年 | 393篇 |
2012年 | 426篇 |
2011年 | 472篇 |
2010年 | 362篇 |
2009年 | 333篇 |
2008年 | 373篇 |
2007年 | 318篇 |
2006年 | 290篇 |
2005年 | 268篇 |
2004年 | 185篇 |
2003年 | 169篇 |
2002年 | 232篇 |
2001年 | 209篇 |
2000年 | 154篇 |
1999年 | 133篇 |
1998年 | 106篇 |
1997年 | 81篇 |
1996年 | 46篇 |
1995年 | 57篇 |
1994年 | 61篇 |
1993年 | 50篇 |
1992年 | 55篇 |
1991年 | 56篇 |
1990年 | 29篇 |
1989年 | 21篇 |
1988年 | 18篇 |
1987年 | 12篇 |
1986年 | 12篇 |
1985年 | 13篇 |
1984年 | 7篇 |
1983年 | 9篇 |
1982年 | 6篇 |
1981年 | 4篇 |
1980年 | 2篇 |
1957年 | 1篇 |
1943年 | 1篇 |
排序方式: 共有7003条查询结果,搜索用时 15 毫秒
91.
Chunxiao Wang Yu-Xuan Chang Xi Chen Lihuan Bai Heping Wang Yu-Chen Pan Chunqiu Zhang Dong-Sheng Guo Xue Xue 《Molecules (Basel, Switzerland)》2022,27(9)
Excessive inflammatory reaction aggravates brain injury and hinders the recovery of neural function in nervous system diseases. Microglia, as the major players of neuroinflammation, control the progress of the disease. There is an urgent need for effective non-invasive therapy to treat neuroinflammation mediated by microglia. However, the lack of specificity of anti-inflammatory agents and insufficient drug dose penetrating into the brain lesion area are the main problems. Here, we evaluated a series of calixarenes and found that among them the self-assembling architecture of amphiphilic sulfonatocalix[8]arene (SC8A12C) had the most potent ability to suppress neuroinflammation in vitro and in vivo. Moreover, SC8A12C assemblies were internalized into microglia through macropinocytosis. In addition, after applying the SC8A12C assemblies to the exposed brain tissue, we observed that SC8A12C assemblies penetrated into the brain parenchyma and eliminated the inflammatory factor storm, thereby restoring neurobiological functions in a mouse model of traumatic brain injury. 相似文献
92.
We synthesize LiTal-x FexO3-σ (LTFO) remain single phase up to x = 0.09 ceramics by the conventional solid-state reaction method. The samples The magnetic measurements show that the doping of Fe successfully realizes ferromagnetism of LTFO at room temperature. The dielectric measurements indicate that LTFO is ferroelectric, similarly to LiTaO3 (LTO), but its ferroelectric Curie temperature seems to decrease with the increasing Fe content. By means of doping Fe ions into LTO, the coexistence of spontaneous electric polarization and spontaneous magnetic moment is realized at room temperature. 相似文献
93.
This paper analytically investigates the interaction of light
filaments generated by a femtosecond laser beam in air. It obtains the
Hamiltonian of a total laser field and interaction force between two
filaments with different phase shifts and crossing angles. The
property of the interaction force, which leads the attraction or
repulsion of filaments, is basically dependent on the phase shift
between filaments. The crossing angle between two filaments can only
determine the magnitude of the interaction force, but does not
change the property of the force. 相似文献
94.
Effects of Organic Acids on the Release of Fruity Esters in Water: An Insight at the Molecular Level
It is well known that organic acids (OAs) could affect the flavour of fruit juices and beverages. However, the molecular mechanism of aroma release is still unclear. In this study, the effects of citric acid (CA), L-(-)-malic acid (MA) and L-lactic acid (LA) on the release of six selected esters and their sensory perception were investigated by means of HS-GC-MS analyses and odour detection threshold determination, respectively. Meanwhile, the density functional theory (DFT) calculation was employed to explore the interaction modes between esters and OAs. HS-GC-MS analyses showed that the concentration and the type of OAs regulated the release of esters. The results were basically consistent with the detection threshold change of those esters. The DFT calculation suggested that the main intermolecular interaction was hydrogen bonds, and several esters could form a ternary ring structure with OAs through hydrogen bonds. The interactions can induce the different release behaviours of esters in OAs water solution. The number of carboxyl functional groups in OAs and the spatial conformation of esters appeared to influence the magnitude of the interaction. The above results demonstrated the mechanism of OAs affecting the release of esters and indicated a possible flavour control way by using different OAs and OA concentrations. 相似文献
95.
Ray L. Frost Yunfei Xi Ricardo Scholz Andrés López Fernanda M. Belotti Mário L. S. C. Chaves 《Phosphorus, sulfur, and silicon and the related elements》2013,188(11):1526-1534
Abstract The metal lithium is very important in industry, including lithium batteries. An important source of lithium besides continental brines is granitic pegmatites as in Australia. Lithiophilite is a lithium and manganese phosphate with chemical formula LiMnPO4 and forms a solid solution with triphylite, its Fe analog, and belongs to the triphylite group that includes karenwebberite, natrophilite, and sicklerite. The mineral lithiophilite was characterized by chemical analysis and spectroscopic techniques. The chemical is: Li1.01(Mn0.60, Fe0.41, Mg0.01, Ca0.01)(PO4)0.99 and corresponds to an intermediate member of the triphylite-lithiophilite series, with predominance of the lithiophilite member. The mineral lithiophilite is readily characterized by Raman and infrared spectroscopy. 相似文献
96.
Lan-Hua Wei Yong-Bing He Jin-Long Wu Xiao-Jun Wu Ling-Zhi Meng Xi Yang 《Supramolecular chemistry》2013,25(8):561-567
Two colorimetric thiourea-based chemsensors with two relatively rigid arms, 2A and 2B, were synthesized. Their binding abilities with halide anions, AcO?, [Formula: See Text] were studied by UV-Vis spectroscopy in DMSO. The two sensors showed a notable selective color response to F? anion from colorless to green-yellow in recognition. The structures of the two sensors and their binding behaviors are discussed. The association constants were calculated by nonlinear fittings of 1:1, 1:2 or 1:1 to 1:2. 相似文献
97.
建立了气相色谱-质谱联用法定性和定量分析塑料中环己烷1,2-二甲酸二异壬酯(DINCH)的方法。考察了DINCH分子离子的质谱断裂过程,并建立了快速鉴定塑料中DINCH的理论方法。通过对不同溶剂提取效率的对比,采用二氯甲烷作为最佳提取溶剂。在优化条件下,该方法的线性范围为0.24~1.60 mg/L,相关系数为0.998,定量下限(S/N=10)为1.2 mg/kg。在加标水平为80~400 mg/kg时,4种不同塑料(PE、PP、PU、PVC)的回收率和相对标准偏差分别为82%~113%和1.1%~9.0%。将该方法用于实际塑料样品的检测,结果满意。 相似文献
98.
蔬菜中重金属含量测定方法的研究状况 总被引:1,自引:0,他引:1
综述了目前测定植株中重金属含量的4种主要方法,包括原子荧光光谱法(AFS)、原子吸收分光光度法(AAS)、电感耦合等离子体发射光谱法(ICP-AES)、电感耦合等离子体质谱法(ICP-MS)。分析了不同方法测定植株中重金属含量的原理、适用条件和研究现状,总结了其优缺点。得出电感耦合等离子体质谱法因其性能较强、实用性好的特点而在植株中的重金属含量测定方面具有明显的优势。同时展望了植株中重金属含量测定方法的发展前景。 相似文献
99.
100.
Xi‐Kai Shu Jia Li Feng Liu Xiao‐Jing Lin Xiao Wang Chun‐Xia Song 《Journal of separation science》2013,36(16):2680-2685
This study aimed to seek an efficient method to extract and purify yunaconitine and 8‐deacetylyunaconitine from Aconitum vilmorinianum Kom. by accelerated solvent extraction combined with pH‐zone‐refining counter‐current chromatography. The major extraction parameters for accelerated solvent extraction were optimized by an orthogonal test design L9 (3)4. Then a separation and purification method was established using pH‐zone‐refining counter‐current chromatography with a two‐phase solvent system composed of petroleum ether/ethyl acetate/methanol/water (5:5:2:8, v/v) with 10 mM triethylamine in the upper phase and 10 mM HCl in the lower phase. From 2 g crude extract, 224 mg of 8‐deacetylyunaconitine (I) and 841 mg of yunaconitine (II) were obtained with a purity of over 98.0%. The chemical structures were identified by ESI‐MS and 1H and 13C NMR spectroscopy. 相似文献