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941.
Synthesis of linear polyphosphonates and polyphosphonamides is achieved by polycondensation in solution of aromatic diols and diamines with alkyldiphosphonyl tetrachlorides, in the presence of a hydrochloric acid trapping agent (triethylamine). The main limiting factors for chain growth are the insolubility of the polymers and the occurrence of side reactions.  相似文献   
942.
943.
In this communication, the structural analysis of six synthetic O-Linked amphiphilic cholesteryl polyethoxy neoglycolipids containing N-acetyl-D-glucosamine was performed by electrospray ionization mass spectrometry in the positive ion mode, with a QqTOF-MS/MS hybrid instrument. The MS/MS analyses provided evidence for the "in situ" formation, in the collision cell of the tandem mass spectrometer, of an unexpected and unique [C-glycoside]+ product ion, resulting from an ion-molecule reaction between the N-acetyl-D-glucosamine oxonium ion and the neutral cholesta-3,5-diene molecule. Quasi MS3 analysis of this ion resulted in the dissociation of the precursor [C-glycoside]+ ion, which produced the expected third generation N-acetyl-D-glucosamine oxonium and the protonated cholesta-3,5-diene product ions.  相似文献   
944.
Oriented stable binding of functional proteins on surfaces is of fundamental interest for receptor/ligand studies in atomic force microscopy (AFM) and surface plasmon resonance (SPR) experiments. Here we have chosen the His6-tagged carboxyl-tail (C-tail) of the alpha1c-subunit of the L-type Ca2+ channel and calmodulin (CaM) as its cognitive partner as a model system to develop a new functional surface. Covalently attached self-assembled monolayers on ultraflat gold containing NTA-thiols to which the His6-tagged C-tail was bound and thiols with triethylene-glycol groups as matrix-thiols represented the system of choice. The topography of this surface was characterized using AFM; its ability to bind C-tail proteins oriented and stable was confirmed by SPR measurements and by complementary force spectroscopy experiments with a CaM4-construct covalently attached to the tip. The developed anchoring strategy can now be used to study receptor/ligand interactions in general applying force spectroscopy and SPR on His6-tagged proteins oriented immobilized onto this new NTA-functionalized self-assembled monolayer.  相似文献   
945.
Derivatives of new polydienic systems have been isolated. Two [2]benzothienophthalazines, nitrogenous analogues of unknown anthra[2,3-c]thiophens are described. A furo[3,4-g]-phtalazine and a thieno[3,4-g]phthalazine are isolated. These different compounds react with philodienes. The first tetraza-2,3,8,9-naphthacenes have been synthesized. Structures of these compounds are proved by chemical and spectrographical methods.  相似文献   
946.
Crystal structures of three Ni(CN)(4)(2)(-) salts all with eclipsed ligands and varying axial stacking arrangements are presented. The absorption spectra of all three salts show a slight red shift in the x,y-polarizations and a large red shift in their z-polarizations upon crystallization from solution. Semiempirical ZINDO calculations provide a good model of the solid state, even with only a three-molecule segment, allowing reproduction of the red-shifting and intensity increase upon crystallization found experimentally. The modified nickel beta(s,p) bonding parameter of -5 found appropriate for Ni coordination in our previous studies of single Ni(CN)(4)(2-) planes and a helically stacked Cs(2)[Ni(CN)(4)].H(2)O crystal was changed to -3 for the more parallel-stacked Ni(CN)(4)(2-) planes in this case, while beta(d) was retained at -41. Crystal data are as follows: Na(2)[Ni(CN)(4)].3H(2)O, triclinic space group P1, a = 7.2980(10) A, b = 8.8620(10) A, c = 15.132(2) A, alpha = 89.311(5) degrees, beta = 87.326(5) degrees, gamma = 83.772(6) degrees, V = 971.8(2) A(3), T = 100 K, Z = 4, R = 0.024, R(w) = 0.064; Sr[Ni(CN)(4)].5H(2)O, monoclinic space group C2/m, a = 10.356(2) A, b = 15.272(3) A, c = 7.1331(10) A, beta = 98.548(12) degrees, V = 1115.6(3) A(3), T = 100 K, Z = 4, R = 0.024, R(w) = 0.059; Rb(2)[Ni(CN)(4)].1.05H(2)O, triclinic space group P1, a = 8.6020(10) A, b = 9.6930(10) A, c = 12.006(2) A, alpha = 92.621(6) degrees, beta = 94.263(6) degrees, gamma = 111.795(10) degrees, V = 924.0(2) A(3), T = 100 K, Z = 4, R = 0.034, R(w) = 0.067.  相似文献   
947.
Partial methylation of methyl N-acetyl-β-d-neuraminate methyl glycoside using methyl iodide and silver oxide gives a mixture of methyl ethers of methyl N-acetyl-N-methyl-β-d-neuraminate methyl glycoside, which was fractionated by chloroform-water partition followed by preparative column chromatography on silica gel. After trimethylsilylation of the fractions, gas-liquid chromatography on OV-101 and mass spectrometry facilitated the identification of 13 methyl ethers.  相似文献   
948.
Reaction of R---N=C=N---R (R=p-Me-C6H4) and R---P==C=P---R (R=2,4,6-tBu3C6H2) with the di-iron aminocarbene complex [Fe2(CO)7{1μ-C(Ph)C(NEt2)}] (1c) gave corresponding complexes [Fe2(CO)6{C(Ph)C(NEt2)C(NC6H4Me)N (C6H4Me)}] (2) and [Fe2(CO)6{C(Ph)C(NEt2)C(PC6H2tBu3)P(C6H2tBu3)}] (4), resulting from a coupling reaction with carbon-carbon bond formation. [Fe2(CO)5(CNC6H4Me){C(Ph)C(NEt2)N(C6H4Me)}], complex 3, obtained in the reaction with R---N=C=N---R, resulted from C=N bond rupture insertion of a nitrene fragment into the Fe=C bond. Complexes 2–4 were characterized by X-ray diffraction. The different geornetries of complexes 2 and 4 are discussed. The formation of these complexes may be explained by cycloaddition on the Fe =C metal-carbene bond.  相似文献   
949.
The molecular and electronic structures of the electron transfer series of four-coordinate square-planar nickel complexes with the ligand o-phenylenebis(N'-methyloxamidate), [NiL]z (z = 2-, 1-, 0), have been evaluated by DFT and TDDFT calculations, and most of their experimentally available structural and spectroscopic properties (X. Ottenwaelder et al., Dalton Trans., 2005, DOI: 10.1039/b502478a) have been reasonably reproduced at the B3LYP level of theory. The anionic species [NiL]2- and [NiL]- are genuine low-spin nickel II and nickel III complexes with diamagnetic singlet (S = 0) and paramagnetic doublet (S = 1/2) states, respectively. The nickel III complex presents shorter Ni-N(amidate) bond distances (1.85-1.90 A) than the parent nickel II complex (1.88-1.93 A) and characteristic LMCT bands in the NIR region (lambda max = 794 and 829 nm) while the analogous MLCT bands for the nickel(II) complex are in the UV region (lambda max = 346 and 349 nm). The neutral species [NiL] is a nickel III o-benzosemiquinonediimine pi-cation radical complex with a diamagnetic singlet (S = 0) and a paramagnetic triplet (S = 1) states fairly close in energy but fundamentally different in orbital configuration. The singlet metal-radical ground state results from the antiferromagnetic coupling between the 3d(yz) orbital of the Ni III ion (S(M) = 1/2) and the pi(b) orbital of the benzosemiquinone-type radical ligand (S(L) = 1/2), which have a large overlap and thus strong covalent bonding. The triplet metal-radical excited state involves the ferromagnetic coupling between the Ni III 3d(zx) orbital and the benzosemiquinone-type pi(b) orbital, which are orthogonal to each other. The singlet and triplet states of the nickel III pi-cation radical complex possess characteristic quinoid-type short-long-short alternating sequence of C-C bonds in the benzene ring, as well as intense MLCT transitions in the VIS (lambda max = 664 nm) and NIR (lambda max = 884 nm) regions, respectively.  相似文献   
950.
The octanickel(II) cluster 2b has been synthesized from the novel ferromagnetically coupled dinickel(II) metallacryptand 1b assembled from the m-phenylene-bis(oxamate) ligand. Complex 2b exhibits a dimer-of-tetramers structure, with two oxamate-bridged propeller-shaped tetranuclear units connected through three meta-substituted phenylenediamidate bridges, giving a metallacryptand core of the meso-helicate type. Complex 2b behaves as a ferromagnetically coupled dimer of two S=2 Ni(II)4 units with appreciable magnetic anisotropy.  相似文献   
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