Entropy generation and MHD natural convection of a nanofluid in an inclined square porous cavity: Effects of a heat sink and source size and location

The effects of a heat sink and the source size and location on the entropy generation, MHD natural convection flow and heat transfer in an inclined porous enclosure filled with a Cu-water nanofluid are investigated numerically. A uniform heat source is located in a part of the bottom wall, and a part of the upper wall of the enclosure is maintained at a cooled temperature, while the remaining parts of these two walls are thermally insulated. Both the left and right walls of the enclosure are considered to be adiabatic. The thermal conductivity and the dynamic viscosity of the nanofluid are represented by different verified experimental correlations that are suitable for each type of nanoparticle. The finite difference methodology is used to solve the dimensionless partial differential equations governing the problem. A comparison with previously published works is performed, and the results show a very good agreement. The results indicate that the Nusselt number decreases via increasing the nanofluid volume fraction as well as the Hartmann number. The best location and size of the heat sink and the heat source considering the thermal performance criteria and magnetic effects are found to be D?=?0.7 and B?=?0.2. The entropy generation, thermal performance criteria and the natural heat transfer of the nanofluid for different sizes and locations of the heat sink and source and for various volume fractions of nanoparticles are also investigated and discussed.     

Non-similar Solution for Natural Convective Boundary Layer Flow Over a Sphere Embedded in a Porous Medium Saturated with a Nanofluid

A boundary layer analysis is presented for the natural convection past an isothermal sphere in a Darcy porous medium saturated with a nanofluid. Numerical results for friction factor, surface heat transfer rate, and mass transfer rate have been presented for parametric variations of the buoyancy ratio parameter N _r, Brownian motion parameter N _b, thermophoresis parameter N _t, and Lewis number L _e. The dependency of the friction factor, surface heat transfer rate (Nusselt number), and mass transfer rate (Sherwood number) on these parameters has been discussed.     

Synergistic Effect of Polyoxometalate and Single Walled Carbon Nanotubes on Peroxidase‐like Mimics and Highly Sensitive Electrochemical Detection of Hydrogen Peroxide

A novel Keggin‐type metatungstate hybrid POMs ((APy)₆[H₂W₁₂O₄₀])/carboxylic acid functionalized single‐walled carbon nanotube based amperometric sensing platform was successfully constructed for the sensitive detection of hydrogen peroxide. A simple and reliable procedure was implemented for the synthesis of new composite materials obtained by the covalent grafting of (APy)₆[H₂W₁₂O₄₀] onto the surface of (SWCNT‐COOH). The synergistic effect of single walled carbon nanotubes on the electrochemical behavior of (APy)₆[H₂W₁₂O₄₀] was evidenced through the increase of the oxidation and reduction peaks of the polyoxometalate. The sensitivity of hydrogen peroxide detection was increased by a factor of 38.5 in presence of SWCNTs, showing their high influence on peroxidase‐like mimics of (APy)₆[H₂W₁₂O₄₀]. The detection limit, the response time, the repeatability and the shelf lifetime were respectively 0.4 μM, 10 s, <4%, 60 days.     

Advances in Fungal Phenaloenones—Natural Metabolites with Great Promise: Biosynthesis,Bioactivities, and an In Silico Evaluation of Their Potential as Human Glucose Transporter 1 Inhibitors

Phenaloenones are structurally unique aromatic polyketides that have been reported in both microbial and plant sources. They possess a hydroxy perinaphthenone three-fused-ring system and exhibit diverse bioactivities, such as cytotoxic, antimicrobial, antioxidant, and anti-HIV properties, and tyrosinase, α-glucosidase, lipase, AchE (acetylcholinesterase), indoleamine 2,3-dioxygenase 1, angiotensin-I-converting enzyme, and tyrosine phosphatase inhibition. Moreover, they have a rich nucleophilic nucleus that has inspired many chemists and biologists to synthesize more of these related derivatives. The current review provides an overview of the reported phenalenones with a fungal origin, including their structures, sources, biosynthesis, and bioactivities. Moreover, more than 135 metabolites have been listed, and 71 references have been cited. SuperPred, an artificial intelligence (AI) webserver, was used to predict the potential targets for selected phenalenones. Among these targets, we chose human glucose transporter 1 (hGLUT1) for an extensive in silico study, as it shows high probability and model accuracy. Among them, aspergillussanones C (60) and G (60) possessed the highest negative docking scores of −15.082 and −14.829 kcal/mol, respectively, compared to the native inhibitor of 5RE (score: −11.206 kcal/mol). The MD (molecular dynamics) simulation revealed their stability in complexes with GLUT1 at 100 ns. The virtual screening study results open up a new therapeutic approach by using some phenalenones as hGLUT1 inhibitors, which might be a potential target for cancer therapy.     

Double-diffusive natural convection in inclined porous cavities with various aspect ratios and temperature-dependent heat source or sink

Laminar double-diffusive natural convective flow of a binary fluid mixture in inclined square and rectangular cavities filled with a uniform porous medium in the presence of temperature-difference dependent heat generation (source) or absorption (sink) is considered. Transverse gradients of heat and mass are applied on two opposing walls of the cavity while the other two walls are kept adiabatic and impermeable to mass transfer. The problem is put in terms of the stream function-vorticity formulation. A numerical solution based on the finite-difference methodology is obtained for relatively high Lewis numbers. Representative results illustrating the effects of the inclination angle of the cavity, buoyancy ratio, Darcy number, heat generation or absorption coefficient and the cavity aspect ratio on the contour maps of the streamline, temperature, and concentration as well as the profiles of velocity, temperature and concentration at mid-section of the cavity are reported. In addition, numerical results for the average Nusselt and Sherwood numbers are presented for various parametric conditions and discussed.     

Transient non-Newtonian flow of a suspension with a compressible particle phase

Equations governing transient two-phase fluid-particle laminar flow over an infinite porous flat plate are developed. Both phases are assumed to behave as non-Newtonian power-law fluids. The mathematical model accounts for particle-phase viscous and diffusive effects. The particles are assumed spherical in shape and having a non-uniform density distribution. The resulting governing equations are nondimensionalized and solved numerically subject to appropriate initial and boundary conditions using an iterative, implicit, tri-diagonal finite-difference method. Graphical results for the displacement thicknesses and the skin-friction coefficients for both the fluid and particle phases are presented and discussed to illustrate special trends of the solutions.     

Effects of chemical reaction on mixed convection flow of a polar fluid through a porous medium in the presence of internal heat generation

This paper reports a detailed numerical investigation on mixed convection flow of a polar fluid through a porous medium due to the combined effects of thermal and mass diffusion. The energy equation accounts for heat generation or absorption, while the nth order homogeneous chemical reaction between the fluid and the diffusing species is included in the mass diffusion equation. The governing equations of the linear momentum, angular momentum, energy and concentration are obtained in a non-similar form by introducing a suitable group of transformations. The final set of non-similar coupled non-linear partial differential equations is solved using an implicit finite-difference scheme in combination with quasi-linearization technique. The effects of various parameters on the velocity, angular velocity, temperature and concentration fields are investigated. Numerical results for the skin friction coefficient, wall stress of angular velocity, Nusselt number and Sherwood number are also presented.     

Perturbation of semi-Browder linear relations by commuting Riesz operators

This paper is devoted to the investigation of the stability of upper semi-Browder, lower semi-Browder and Browder linear relations which satisfy the stabilization property, under commuting Riesz operator perturbations. As applications, we infer the invariance of the corresponding Browder’s essential approximate point spectrum, Browder’s essential defect spectrum and Browder’s essential spectrum under commuting Riesz operator perturbations.     

Steady Natural Convection Flow of a Particulate Suspension Through a Parallel-Plate Channel

A continuum model for two-phase (fluid/particle) flow induced by natural convection is developed and applied to the problem of steady natural convention flow of a particulate suspension through an infinitely long channel. The walls of the channel are maintained at constant but different temperatures. The two-phase model accounts for particle-phase viscous effects. Boundary conditions borrowed from rarefied gas dynamics are employed for the particle-phase wall conditions. Various closed-form solutions for different special cases are obtained. A parametric study of the physical parameters involved in the problem are performed to illustrate the influence of these parameters on the flow and heat transfer aspects of the problem.