SiC晶体生长中气相组分输运特性

针对物理气相传输(PVT)法生长碳化硅(SiC)晶体,建立了一个二维生长动力学模型研究SiC生长腔内气相组分输运特性,该模型考虑了氩气与气相组分之间的流动耦合,Stefan流和浮力影响.研究表明:在压力较低的情况下,自然对流对气相组分的输运过程影响很小,可以忽略,而当压力增高时,自然对流强度显著增大,不可忽略.其次,随着生长温度升高对流的作用增强,生长腔内输运过程由扩散向对流转变,最终对流主导组分的输运过程.随着压力升高对流作用减弱,扩散为气相组分主要输运方式.     

高能量密度型锂离子电池正极材料LiNi0.5Mn1.5O4改性的研究进展

尖晶石镍锰酸锂(LiNi0.5Mn1.5O4)具有工作电压高、结构稳定、适合快充快放等特性成为高能量及高功率密度型正极材料的有力竞争者.结合了近几年的研究报道,介绍了LiNi0.5 Mn1.5O4的结构、制备方法、改性方法及其应用前景,着重介绍了LiNi0.5 Mn1.5O4材料晶型结构对其性能的影响,并指出该材料目前存在的问题和研究重点.     

Ag@CH3NH3PbI3等离激元效应增强钙钛矿太阳能电池性能的数值研究

由于银纳米粒子结构的表面等离激元共振特性对有机无机卤化物钙钛矿的新型太阳能电池性能有一定影响,利用comsol mutiphysics多物理场仿真软件对Ag@CH3 NH3 PbI3纳米粒子等离激元效应增强钙钛矿太阳能薄膜电池性能进行研究,对粒子半径和粒子间距对于能量的影响进行了计算;对光敏层能量增强的机理进行了解释;并对电场分布进行了详细说明.依据实验数据,给出优化后的银纳米粒子阵列和钙钛矿光敏层的厚度以及强度,为实验制备高效稳定的钙钛矿太阳能电池提供理论指导.     

Influences of hyperbranched polyethylenimine on the reactive compatibilization of polycarbonate/polyamide blends

The influences of hyperbranched polyethylenimine(h PEI), which possesses many reactive amino end-groups, on the blending properties of bisphenol-A polycarbonate(PC) and amorphous polyamide(a PA) were systematically investigated. Scanning electron microscopy(SEM) and differential scanning calorimetry(DSC) were used to observe the effect of h PEI on morphologies of PC and a PA phases in bulk blends. While the interfacial fracture toughness between planar PC and a PA layers with and without h PEI was studied by using augmented double cantilever beam(ADCB) method. Results show that the compatibility in PC/a PA blends can be significantly improved by adding a small amount of h PEI, mainly due to the interchange reactions between the polymers leading to the formation of block copolymers, cross-linked polymers and molecules with other constitutions. The augmented double cantilever beam experiments showed that the reactive process drastically reinforced the interfacial adhesion between planar layers of PC and a PA. However, degradation takes place during annealing at 180 °C, which was responsible for the production of small molar mass species of PC.     

离子对反相高效液相色谱法同时测定尿液中复方α-酮酸片的5种有效成分

建立了同时测定尿液中复方α-酮酸片5种有效成分(消旋羟蛋氨酸钙(HMACa)、酮缬氨酸钙(KVCa)、消旋酮异亮氨酸钙(KILCa)、酮亮氨酸钙(KLCa)和酮苯丙氨酸钙(KPACa))的离子对反相高效液相色谱法。分别考察了离子对试剂浓度、缓冲盐浓度和流动相pH值等参数对分离情况的影响。最终采用Waters Symmetry C18色谱柱(250 mm×4.6 mm,5μm);以乙腈和含15 mmol/L四丁基氢氧化铵的20 mmol/L磷酸盐缓冲液(pH 7.0)为流动相进行梯度洗脱,流速为1.0 mL/min;柱温为35℃;检测波长为210 nm。在上述条件下,5种有效成分得到很好的分离,并且不受尿液中内源性基质的干扰,在20~200 mg/L范围内线性关系良好(r≥0.999 0);HMACa、KVCa、KILCa、KLCa和KPACa的检出限(S/N=3)分别为3.0、5.0、3.6、5.7和2.5 mg/L;定量限(S/N=10)分别为9.6、16.7、12.0、19.0和8.3 mg/L;日间、日内精密度均小于7%;平均回收率在86.79%~112.00%之间,RSD小于9%(n=5)。该方法准确,灵敏度高,重现性好,适用于尿液中这5种有效成分的检测。     

国产润滑油的压粘系数和固化压力

润滑油的压粘系数和固化压力是弹流理论应用于摩擦学工程设计的关键试验数据。本文报道了20种国产润滑油的压粘系数和其中16种润滑油的最小固化压力的测定结果,并对不同油田的基础润滑油、不同化学结构的合成润滑油和不同用途的工业润滑油的压粘系数和固化压力进行了分析比较。     

非线性碰摩力对碰摩转子分叉与混沌行为的影响

研究了具有非线性碰摩力的转子局部碰摩的分叉与混沌运动,利用计算机仿真对某发动机转子的碰摩故障进行了数值模拟,讨论了转子系统参数的变化对转子混池运动状态的影响,并与碰摩实验结果进行了比较,发现了具有非线性碰摩力的转子局部碰摩转子系统的各种多周期运动和混沌运动及其演变过程。     

Recent Advances in Synergistic Antitumor Effects Exploited from the Inhibition of Ataxia Telangiectasia and RAD3-Related Protein Kinase (ATR)

As one of the key phosphatidylinositol 3-kinase-related kinases (PIKKs) family members, ataxia telangiectasia and RAD3-related protein kinase (ATR) is crucial in maintaining mammalian cell genomic integrity in DNA damage response (DDR) and repair pathways. Dysregulation of ATR has been found across different cancer types. In recent years, the inhibition of ATR has been proven to be effective in cancer therapy in preclinical and clinical studies. Importantly, tumor-specific alterations such as ATM loss and Cyclin E1 (CCNE1) amplification are more sensitive to ATR inhibition and are being exploited in synthetic lethality (SL) strategy. Besides SL, synergistic anticancer effects involving ATRi have been reported in an increasing number in recent years. This review focuses on the recent advances in different forms of synergistic antitumor effects, summarizes the pharmacological benefits and ongoing clinical trials behind the biological mechanism, and provides perspectives for future challenges and opportunities. The hope is to draw awareness to the community that targeting ATR should have great potential in developing effective anticancer medicines.