A Convenient Synthesis of Pyrazolylpyrazoles Using α-Oxo Ketene S,S- and N,S-Acetals

Aryl-substitutedpyrazolederivativeshavealreadyattractedwideattentioninrecentdecadesbecausetheywerereportedtoshowabroadspectrum0fbi0logicalactivities.Forinstance,severalsubstitutedpyrazolyIpyrazoIesdemonstratedhighpreemergentherbicidalactivityagainstawidevarietyofbroadleafweedspecies"'.Pyraz0lyl-pyrimidinesexhibiteds0mefungicidalactivity'.Fripronil(5-amino-3-cyan0-l-(2',6,-dichloro-4'-trifluoromethylphenyisanewpyrazoleinsecticidethatprovidesexcellentc0ntrolofmanysoilandf0liarinsects0nawidevari…     

A Highly Sensitive Kinetic Spectrophotometric System and Its Analytical Potential for Chromatographic Detection of Metal Ions

Micelles,microemulsions.vesicles,etc.,areorganicmicroheterogeneousmedia.Useofthesemediainanalyticalreactionsfordevelopingnewkinetic-baseddeterminationsorimprovingpreviouslyestablishedkineticmethodshasbeenreported"2.Inrecentyears,amixedmicellarmediumc...     

Side-pumped continuous-wave passively mode-locked Nd:YAG laser by using non-antiresonant SESAM

A new type semiconductor saturable absorber mirror (SESAM), which is not fulfilled antiresonance condition, was used in a side-pumped Nd:YAG laser. Experiment results show that stabilized continuous-wave mode-locking can successfully be obtained in picosecond regime by a nonantiresonant SESAM. Because the bandwidth of picosecond regime mode-locked pulse is not broad; therefore, the antiresonant factor of SESAMs, which are used in picosecond mode-locked lasers, can be omitted when the SESAMs are designed and fabricated. Without the limit of antiresonance condition, the difficulty of design and growth will decrease significantly and there will be more freedom in considering the modulation depth.     

Rate enhancement for nitroxide stable free radical polymerization of n‐butyl acrylate by dodecylbenzenesulfonic acid

Dodecylbenzenesulfonic acid, DDBSA, was chosen as a new rate‐accelerating additive for 2,2,6,6,‐teramethyl‐1‐piperidinyloxy (TEMPO)‐mediated stable free radical polymerization of n‐butyl acrylate (n‐BA) monomers with 2,2′‐azobisisobutyronitrile (AIBN). It was found that the number‐average molecular weight of polymers could reach about ten thousand with a narrow polydispersity index (PDI) of 1.4 in a few minutes, which was faster than other systems reported previously. But, at higher conversion, the molecular weight distribution of polymers became broad, and a bimodal distribution occurred. The macro‐initiators isolated from the former polymers with narrow PDI could be extended by polymerization with monomers by the addition of DDBSA. Furthermore, a proposed kinetic model demonstrated that the decay of the concentration of DDBSA would reduce the living polymer concentration and retard the growth of the polymers, which could be further propagated by the supplement of DDBSA. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 42–49, 2005     

在La2CuO4+y中超导与长程非公度磁有序的共存

铜氧化物超导体的相图具有如下共同特征:未掺杂或很低掺杂浓度对应反铁磁区;最佳掺杂及欠掺杂的低温相是超导区;当掺杂浓度介于上述二者之间时,材料既不超导也不具有反铁磁长程序.一般认为,超导与长程磁有序不能共存.     

DEGENERATE OPTIMAL BASIS GRAPHS IN LINEAR PROGRAMMING

§ 1　IntroductionA graph-theoretic approach for investigating basis transformations in a linear pro-gramming has been historically developed.Let V be the setof all bases with respectto thecolumn vectors of a matrix A.Two bases are called adjacentifthey can be transformed intoeach other by a pivot operation.Denote by E the set of edges each of which is incidentwith a pair of adjacentbases.Then G=(V,E) is called the basisgraph of matrix A(or ofthe corresponding LP) .Tucker[1 ] first called…     

Identification of metabolites of Danggui Buxue Tang in rat urine by liquid chromatography coupled with electrospray ionization time‐of‐flight mass spectrometry

A method coupling liquid chromatography with electrospray ionization time‐of‐flight mass spectrometry (LC/ESI‐TOF/MS) has been developed for rapid and sensitive analysis of rat urinary metabolite profile of Danggui Buxue Tang (DBT), a well‐known Chinese herbal formula. After oral administration of DBT, urine samples were collected during 0–24 h, and then pretreated by solid‐phase extraction. A total of 68 compounds including 13 parent compounds and 55 metabolites were detected in the drug‐containing urines compared with blank urines. The total analytical time was less than 20 min. Metabolites of DBT were identified using dynamic adjustment of the fragmentor voltage to produce structure‐relevant fragment ions. By using this approach, the mass accuracy of precursor and fragment ions was typically within ±5 ppm of the theoretical values, and enabled the identification of 43 metabolites including 27 isoflavanoid and 16 phthalide metabolites. Our results indicated that glucuronidation and sulfation were the major metabolic pathways of isoflavonoids, while glutathione conjugation, glucuronidation and sulfation were the main metabolic pathways of phthalides. No saponin‐related metabolites were detected. The results of the present study provided important structural information relating to the metabolism of DBT. Furthermore, this work demonstrated the potential of the LC/ESI‐TOF/MS approach for identification of metabolites from Chinese herbal medicines in urine. Copyright © 2009 John Wiley & Sons, Ltd.     

Two novel fluorescent calix[4]arene derivatives with benzoazole units in 1,3-alternate conformation for selective recognition to Fe~(3+) and Cr~(3+)

Two novel fluorescent calix[4]arene derivatives 1a and 1b with benzoxazole or benzothiazole units in 1,3-alternate conformation have been synthesized and characterized by IR,~1H NMR,~(13)C NMR and MS.Their complexation properties to different heavy and transition metal ions have been studied by UV-vis spectroscopy and fluorescence spectrometer.Compounds 1a and 1b show selective recognition to Fe~(3+) and Cr~(3+).     

A new macrolide and glycosides from the stem of Sargentodoxa cuneata

A new macrolide glycoside,cuneataside F was isolated from the n-butanol extract of the stem of Sargentodoxa cuneata. The structure was elucidated on the basis of extensive 1D and 2D NMR as well as HRESI-MS spectroscopic analysis.     

New Sesquiterpenes from the Roots and Stems of Aristolochia Mollissima

Two new sesquiterpenes, madolins Y ( 1 ) and Z ( 2 ) were isolated from the dried roots and stems of Aristolochia mollissima, and their structures were determined by spectroscopic methods.