[Cd2(tren)2(dl-alaninato)](ClO4)3: an efficient water-compatible Lewis acid catalyst for chemo-, regio-, and diastereo-selective allylation of various aldehydes

The use of [Cd₂(tren)₂(dl-alaninato)](ClO₄)₃·H₂O (I) (tren = tris(2-aminoethyl)amine) as an efficient water-compatible Lewis acid catalyst for the allylation of aldehydes in aqueous media was described. The reaction proceeded smoothly to afford the corresponding homoallyl alcohols in up to 96% yield. Additionally, cinnamyltributylstannane was selected as the allylation reagent, the regio- and diastereoselectivity of the reaction favors the formation of the γ-product and the anti isomers, respectively.     

Polarization holographic optical recording based on a new photochromic diarylethene compound

A new unsymmetrical photochromic diarylethene, namely1-[2-methyl-5-(p-N,N-dimethylaminophenyl)-3-thienyl]-2-[2-methyl-5-(3-methoxylphenyl)-3-thienyl] perfluorocyclopentene (1a), was synthesized. The compound showed good photochromism, high sensitivity and remarkable fatigue-resistance both in solution and in poly(methyl methacrylate) (PMMA) matrix with UV/Vis light irradiation. The absorption maximum of its closed-ring isomer was observed at 624 nm in PMMA amorphous film. It is a nice match for the wavelength of the recording laser (633 nm). Using this target compound as recording medium, four types of polarization holographic optical recordings were performed successfully using a He-Ne laser. The results showed that only the orthogonal circular polarization recording could obtain a hologram with high diffraction efficiency and high signal-to noise-ratio. With multiplexing recording technology, three types of polarization multiplexing holographic optical recordings, including angular multiplexing, polarization multiplexing, and angular plus polarization multiplexing holographic recording, were also carried out perfectly based on its photoinduced anisotropic phenomenon accompanying the photochromic reaction by photoirradiation. The results demonstrate that the multiplexing recording technology is an effective method to improve recording capacity when using diarylethene 1 as recording medium.     

An efficient synthesis of ring‐fused indoles via copper‐catalyzed tandem reaction of N‐(o‐alkynylphenyl)imines

A copper‐catalyzed tandem intramolecular cyclization‐addition reaction of N‐(o‐alkynylphenyl)imines is disclosed. This strategy offers a simple and promising method for accessing ring‐fused indoles. Copyright © 2010 John Wiley & Sons, Ltd.     

Simultaneous determination of seven lignans in Justicia procumbens by high performance liquid chromatography–photodiode array detection using relative response factors

A simple and sensitive HPLC coupled with photodiode array (HPLC–PDA) method was developed for simultaneous determination of seven lignans in Justicia procumbens using relative response factors (RRFs). The chromatographic separation was performed on a Shiseido Capcell Pak C₁₈ column (250 × 4.6 mm id, 5 μm), a gradient elution of acetonitrile/water, and a photodiode array detector. The column temperature was maintained at 35°C and the detection wavelength was set at 256 nm. Chinensinaphthol methyl ether was selected as the reference compound for calculating the relative response factors of the lignans. It has shown that the RRFs for lignans are quite similar at 256 nm of detection under different analytical conditions (different columns and HPLC instruments). Using RRFs, not every lignan is needed as a reference standard, making the method ideal for rapid, routine analysis, especially for those laboratories where lignans standards are not readily available. An economic and practicable HPLC method using RRFs was established for the determination of seven lignans in J. procumbens. This method not only can determine multiple indexes in traditional Chinese medicines (TCMs) simultaneously, but also resolve the problem of lacking of chemical standards. It will be a good quality evaluation method and pattern for TCMs.     

Synthesis of starfish-like Cu2O nanocrystals through ��-irradiation and their application in lithium-ion batteries

In this study, single-crystalline starfish-like cuprous oxide (Cu₂O) nanocrystals with the backbones lengths in the range of 660 nm~16 ??m are successfully prepared through ??-irradiation, the cetyltrimethylammonium bromide (CTAB) is used as a capping material or soft colloidal templates. Without the addition of CTAB in the reaction system, irregular Cu₂O nanoclusters were obtained and their diameter is about 200 nm~1 ??m. Controlling the concentration ratio of CTAB to the copper ions, starfish-like morphology of Cu₂O can be obtained in high yield. Their structures are characterized by X-ray diffraction, scanning electron microscopy, and high-resolution transmission electron microscopy. The possible growth mechanism of the starfish structure is discussed in the text. For potential application in lithium-ion batteries, an electrode made of the starfish-like Cu₂O shows excellent electrochemical cycling performance and high-rate capability. Compared with the Cu₂O nanoclusters, the starfish-like Cu₂O exhibits an improved electrochemical cycling stability. The capacity of the starfish-like Cu₂O can maintain 340 and 215 mAh g^?1 after 50 cycles at the rate of 0.1 C and 5 C, respectively. The reversible capacity holds 60% as the discharge?Ccharge rate even increases by 50 times.     

光学综合孔径望远镜成像分析及计算机仿真

阐述了光学综合孔径(OSA)望远镜成像原理以及综合孔径望远镜的几种实现形式；采用快速傅里叶变换(FFT)算法得到了任意子孔径综合模式下的点扩展函数(PSF)和光学传递函数(OTF)分布；从子孔径结构排列、共相位、图像恢复几个方面论述了光学综合孔径的成像特征。初步分析了稀疏率、填充因子、“实际截止频率”等因素对光学综合孔径望远镜成像的影响。分析和仿真结果表明：光学综合孔径通过相干成像不但可以突破传统单孔径系统的口径局限获得极高的成像分辨率，而且对于实现空间光学遥感系统轻量化和模块化都具有重要意义。     

金属钯/铂卟啉室温燐光探针在生物医学领域的应用研究

钯 铂 卟啉络合物在室温下发射长寿命 (ms)、长波长的光 ,这些特点使其在生物分析方面成为有用的探针。本文综述了该探针在光免疫标记、肿瘤诊断、DNA测定、生物传感器及其它方面的研究进展。引用文献 4 3篇     

DYNAMIC SIMULATION ANALYSIS OF CAPTURE AND BUFFER SYSTEM BASED ON CLAW-TYPE DOCKING MECHANISM

现有在轨服务的对接机构由于其尺寸大、结构复杂、对接目标单一等局限性因素,无法很好地为后续我国探月工程任务提供有力支撑,且受限于运载能力,对接机构的轻量化也是必不可少的一项环节.为研究可服务于未来月球空间站以及载人登月等高轨道任务的对接机构,设计了一种新型抱爪式对接机构,其采用异体同构周边式构型,可以实现主/被动飞行器之间的互换.利用 V 型槽与爪钩等结构部件实现飞行器对接过程中的捕获以 及能量消耗功能,从而实现两飞行器之间的稳固联接.该对接机构具备尺寸小、重量轻、结构简单、功能易实现等优势. 对其捕获缓冲系统进行了动力学分析,计算了缓冲元器件的参数对其捕获性能的影响,在 ADAMS 完成了数字虚拟样机的建立,结合实际两种典型的对接初始条件工况进行了仿真研究.研究结果表明,两种工况下的对接过程能量消耗满足设计要求,能够以较小的 V 型槽的碰撞力完成捕获,结果证明了捕获缓冲系统的可行性以及该构型对接机构具备较好实现任务的能力.     

Rational Design of a Humanized Glucagon‐Like Peptide‐1 Receptor Agonist Antibody

Bovine antibody BLV1H12 possesses a unique “stalk–knob” architecture in its ultralong heavy chain CDR3, allowing substitutions of the “knob” domain with protein agonists to generate functional antibody chimeras. We have generated a humanized glucagon‐like peptide‐1 (GLP‐1) receptor agonist antibody by first introducing a coiled‐coil “stalk” into CDR3H of the antibody herceptin. Exendin‐4 (Ex‐4), a GLP‐1 receptor agonist, was then fused to the engineered stalk with flexible linkers, and a Factor Xa cleavage site was inserted immediately in front of Ex‐4 to allow release of the N‐terminus of the fused peptide. The resulting clipped herceptin–Ex‐4 fusion protein is more potent in vitro in activating GLP‐1 receptors than the Ex‐4 peptide. The clipped herceptin–Ex‐4 has an extended plasma half‐life of approximately four days and sustained control of blood glucose levels for more than a week in mice. This work provides a novel approach to the development of human or humanized agonist antibodies as therapeutics.     

基于多摄像机的航空器滑行冲突检测研究

对机场场面航空器滑行冲突检测进行了研究,分析了基于多摄像机的航空器滑行冲突检测流程,基于图像识别和目标跟踪技术,提取航空器的滑行轨迹,提出了基于DCPA(distance of closest point of approach)和TCPA(time of closet point of approach)的滑行冲突检测模型,开发了基于多摄像机的航空器滑行冲突检测原型系统并应用于西南某通航机场;实验结果表明,基于多摄像机视频目标跟踪和冲突检测模型可有效地检测机场场面航空器的滑行冲突,可作为中小机场主要监视手段以及大型机场场监雷达系统的辅助,防止航空器机场滑行冲突,提高机场场面运行安全和效率。