Temperature-dependent changes in erythrocytes' cytosol state during natural and artificial hypobiosis

At present, the question of how the structural state of the erythrocyte cytosol is arranged to maintain essential permeabilities successfully both at normal temperature and during periods with a significant body temperature reduction during hypobiosis remains unanswered. In the present work, we performed comparative investigations of temperature-dependent changes in the cytosol state of erythrocytes from animals subjected to natural (winter hibernating ground squirrels) or artificial hypobiosis. The cytosol state was evaluated by the ESR method of spin probes (TEMPON) within the temperature range of 0-50 degrees C. Erythrocyte resistance to acid hemolysis, which is limited by the permeability of membranes for protons and the state of the anion channel, were determined using the method described by Terskov and Getelson [Biofizika 2 (1957) 259]. A change in cytosol microviscosity of erythrocytes was found as well as a temperature-dependent increase in acid resistance of erythrocytes. Our investigations allow us to conclude that physiological changes occurring in a mammalian organism during natural and artificial hypobiosis are accompanied by structural modifications of the erythrocyte cytosol. The temperature range where these modifications are observed (8, 15, 40 degrees C) suggests that the most probable modifying link is spectrin and/or the sites of its interaction with membrane. The interaction of cytoskeletal components with the cell membrane plays a key role in regulation of membrane permeability, suggesting an important role of this interaction in the adaptive reactions of erythrocytes.     

A new synthetic route to substituted 1-fluoro-1-cyclopropanecarboxylates

Substituted 6-fluoro-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylates were obtained as a mixture of the exo- and endo-isomers by reaction of substituted 6,8-dioxo-2,3,7-triazabicyclo[3.3.0]oct-3-en-4-carboxylates with N-fluoropyridinium tetrafluoroborate.     

On Generalized Fibonacci Quaternions and Fibonacci-Narayana Quaternions

In this paper, we investigate some properties of generalized Fibonacci quaternions and Fibonacci-Narayana quaternions in a generalized quaternion algebra.     

On the theory of smectic textures

The strains in smectics are considered beyond the small-angle approximation. The energies of confocal and conical textures are determined.     

Naum Il'ich Akhiezer (on the 100th Anniversary of His Birth)

Ukrainian Mathematical Journal -     

Application of Information Technologies and Programming Methods of Embedded Systems for Complex Intellectual Analysis

An information model is outlined, which represents an intelligent system of metallographic analysis in the form of a set of subsystems, the interaction of which ensures the performance of metallographic analysis functions. The structure of the information storage subsystem for metallographic analysis is presented. The deployment model of an intelligent metallographic analysis system is proposed and described. The paper outlines the approach to the presentation of an expert subsystem for metallographic quality control of metals based on a neural network. The process of finding a close precedent in metallographic analysis with reference to a multilayer neural network is described. An intelligent metallographic analysis system is described, which based on proposed information model. A specialized software of an intelligent metallographic analysis system is presented. The functioning results of the developed system for processing images of steel microstructures to determine the steel quantitative parameters is presented.     

Condensed-State Physics Structure and Phase Composition of a Coating Synthesized from Ti–Ni–Ti Laminate on Tini Substrate

Russian Physics Journal - A gradient magnetron-sputtered three-layer laminated Ti–Ni–Ti coating is formed by the method of reaction synthesis on a titanium nickelide substrate. The...