Acylated flavonoid glycosides from Barringtonia racemosa

Abstract

Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G–I (1–3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (3) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC₅₀ of 52.48?±?1.04?µM.     

离子色谱法测定水果及其树叶的含氯量

本文提出用离子色谱法测定水果及其树叶中氯含量的方法,在IC-PAK阴离子柱上,用4 mmol/L邻苯二甲酸(pH4.5)作流动相进行洗脱,电导检测器检测。方法简便、快速,灵敏、准确。氯的最小检出量为0.14μg,相对标准偏差为2.4%,回收率为99.4%。     

高温煤焦油的超临界萃取分馏研究

采用正戊烷溶剂,在超临界状态下,于220℃和5MPa~15MPa循序升压条件下,将高温煤焦油萃取分馏为10个液相窄馏分和1个固相沥青产物;切割深度达78.36%,萃余沥青收率为21.64%,明显低于常规蒸馏沥青收率。研究发现,所用高温煤焦油的初馏分萃取收率最高,随着萃取压力的增加,较低压力段一次萃取液相馏分的收率迅速减少;压力达到10 MPa,液相馏分总收率趋于峰值。元素分析和色质联用分析数据表明,随着萃取压力的增加,一次萃取获得窄馏分的碳氢原子比逐渐增加,平均环数和相对分子质量均逐渐增大,萃取馏分逐渐变重。     

New diterpenoid glucosides from Siegesbeckia pubescens

Plants of the genus Siegesbeckia are annual herbs widely distributed in tropical and temperate zones and they are used as a traditional medicine to treat rheumatic arthritis, hypertension, malaria, neurasthenia and snake-bite in China. In previous papers, we reported on five new ent-kaurane and ent-pimarane diterpenoids, siegesbeckioside, siegesbeckiol and siegesbeckic acid1, orientalin A and B, and eight know compounds2,3. The present paper describes the isolation and structural elucidation …     

反相高效液相色谱法测定肾复康胶囊中的野黄芩苷和芦丁

建立了肾复康胶囊中野黄芩苷和芦丁的反相高效液相色谱测定方法。以甲醇-水为提取溶剂,采用超声提取法对样品进行前处理。以0.02 mol/L磷酸二氢钾缓冲溶液(含1.0％（体积分数）冰醋酸)-甲醇（体积比为63∶37）为流动相,于330 nm波长下检测,肾复康提取液中野黄芩苷和芦丁可达基线分离,分析时间在20 min内。野黄芩苷和芦丁在10 ~300 mg/L内,其峰面积与浓度之间线性关系良好,目标物的加标回收率大于98％。该方法适用于肾复康胶囊及相关药材中野黄芩苷和芦丁黄酮类化合物的测定和质量控制。     

几种吸附树脂对五氯酚钠吸附性能的研究

研究了几种树脂对五氯酚钠的吸附能力,其中戊二醛交联的壳聚糖树脂不仅有较好的吸附效果,动态吸附容量为187.5mg/g干树脂,而且易洗脱,洗脱率高达90%以上。     

交联壳聚糖树脂对部分尿毒症毒物的吸附性能研究

用反向悬浮的方法制备了戊二醛交联壳聚糖树脂吸附剂,并对制得的球形吸附剂用NaBH4进行了氢化还原处理,以提高其在使用环境下的化学稳定性。扫描电子显微镜(SEM)分析表明,吸附剂的表面形态构成了吸附的微观基础。通过对部分尿毒症毒性物质的吸附研究发现,本文研制的壳聚糖吸附剂对这些目标物均产生了一定的吸附作用,吸附平衡时间符合临床要求,其对3种小分子尿毒症毒性物质的吸附能力依肌酐、尿酸、尿素的次序递增,而对促皮质素(ACTH)的吸附量则达到了13.04mg/g,显示了该类吸附剂应用于临床治疗的潜在价值     

一种新型温湿度测量系统的设计

为了解决传统温湿度测量系统存在的标定和校准过程复杂而引起的精度不高的问题,文中介绍了一种新型的温湿度测量系统。该系统由瑞士SENSIR ION公司新生产的SHT11数字式温湿度传感器和日本NEC公司生产的78F9177Y单片机为核心组成,具有电路简单、免标定、精度高和可靠性好等优点。     

High selectively oxidative bromination of toluene derivatives by the H_2O_2-HBr system

An aqueous solution of hydrogen peroxide and hydrogen bromide illuminated by a 60 W incandescent light bulb serves as a source of bromine radicals.Various substituted toluenes（NO₂,Cl,Br,H,CH₃） were high selectively brominated at the benzyl position for monobromination in CH₂C1₂ at ice water with catalyst free.This simple but effective bromination of toluene derivatives with an aqueous H₂O₂-HBr system is characterized with the use of inexpensive reagents and a lower impact on the environment, which make it a good alternative to the existing bromination methods.