Validation of a new measuring system for water turbidity field measurements

Turbidity is an essential parameter for describing water quality by direct and indirect impacts on fish, invertebrates and aquatic plants. Currently, environmental monitoring measurements are carried out with appropriate quality by accredited testing laboratories, but there is also a need for employing the third sector, i.e. citizens and voluntaries in environmental monitoring. A device called “Secchi3000” was developed as a low-cost and simple-to-operate tool so that water quality measurements can also be carried out by non-experts and citizens. The measurement using the new device is simple: The user fills the container with water and places the measurement structure in the container. The user takes a photograph with the camera on a mobile phone through a hole in the lid. The software sends the photograph to a server, which analyses the photographs automatically. Finally, the results are returned to the user’s mobile phone and stored on a database for further analysis. In this study, the measuring system for turbidity measurements in natural waters was validated. Validation included an estimation of the limit of quantification, investigations of the influence of water colour and illumination conditions on turbidity measurement values and the estimation of measurement uncertainty. A comparison of turbidity results obtained with the new device and laboratory instrument in natural water samples was carried out, and turbidity values obtained with different mobile phones were compared. According to the validation results, the new device was appropriate for the measurement of turbidity lower than 7 FNU (Formazine Nephelometric Unit). An algorithm applied for present turbidity calculations is not fully suitable for higher turbidities. For potential routine use, this is not a major problem, since most Finnish natural waters have turbidities lower than 7 FNU. For official monitoring purposes, the limit of the quantification needs to be lower than presently achieved (1.7 FNU). Although the present configuration of the Secchi3000 device is not yet fully suitable for official environmental monitoring, it will already enable the involvement of the third sector in water quality monitoring, and in this way, citizens’ observations could then serve at least as supplementary information for reporting and surveys.     

Direct Assembly of 2‐Oxazolidinones by Chemical Fixation of Carbon Dioxide

The reaction of β‐ and γ‐haloamines with carbon dioxide to give pharmaceutically relevant 2‐oxazolidinones and 1,3‐dioxazin‐2‐ones, was found to proceed efficiently in the presence of a base and in the absence of catalyst. After optimization of reaction conditions, the system was successfully expanded to a variety of haloamines, even at multigram scale. The reaction was further studied in silico by DFT calculations.     

One-pot citral transformation to menthol over bifunctional micro- and mesoporous metal modified catalysts: Effect of catalyst support and metal

Citral transformation to menthols was conducted in liquid phase over Ni supported H-MCM-41 and H-Y. The highest selectivity to four different stereoisomers of menthol and to (±)-menthols over Ni-H-MCM-41 were 54 and 38%, respectively. The effect of different metals (Ni, Ir, Ru, Pd) was studied over H-MCM-41. The selectivity to menthols decreased in the following order: Ni > Pd > Ru > Ir.     

Epi-convergent discretizations of stochastic programs via integration quadratures

Summary. The simplest and the best-known method for numerical approximation of high-dimensional integrals is the Monte Carlo method (MC), i.e. random sampling. MC has also become the most popular method for constructing numerically solvable approximations of stochastic programs. However, certain modern integration quadratures are often superior to crude MC in high-dimensional integration, so it seems natural to try to use them also in discretization of stochastic programs. This paper derives conditions that guarantee the epi-convergence of the resulting objectives to the original one. Our epi-convergence result is closely related to some of the existing ones but it is easier to apply to discretizations and it allows the feasible set to depend on the probability measure. As examples, we prove epi-convergence of quadrature-based discretizations of three different models of portfolio management and we study their behavior numerically. Besides MC, our discretizations are the only existing ones with guaranteed epi-convergence for these problem classes. In our tests, modern quadratures seem to result in faster convergence of optimal values than MC.Mathematics Subject Classification (2000): 90C15, 49M25The work of this author was partially supported by The Finnish Foundation for Economic Education under grant no. 21599 and by Finnish Academy under contract no. 3385     

Silicon micropillar array electrospray chip for drug and biomolecule analysis

We have developed a lidless micropillar array electrospray ionization chip (microPESI) combined with mass spectrometry (MS) for analysis of drugs and biomolecules. The microPESI chip, made of silicon, contains a sample introduction spot for a liquid sample, an array of micropillars (diameter, height, and distance between pillars in the range of 15-200, 20-40, and 2-80 microm, respectively), and a sharpened tip for direct electrospray formation. The microchips were fabricated using deep reactive ion etching (DRIE) which results in accurate dimensional control. The chip, providing a reliable open-channel filling structure based on capillary forces and a electrospray emitter tip for ionization, allows an easy operation and reliable, non-clogging liquid transfer. The microPESI chip can be used for a fast analysis using single sampling or for continuous infusion measurements using a syringe pump for sample introduction. The microPESI-MS shows high sensitivity, with limit of detection 30 pmol/L (60 amol or 28 fg) for verapamil measured with tandem mass spectrometry (MS/MS) and using a sample volume of 2.5 microL. The system shows also good quantitative linearity (r2 > 0.99) with linear dynamic range of at least six orders of magnitude and good ion current stability (standard deviation <5%) in 1-h continuous flow measurement. The microPESI-MS is shown to be a very potential method for direct analysis of drugs and biomolecules.     

A Facile Deacyloxylation of Aromatic Acyloin Acetates with Phenyl Trimethylsilyl Selenide

The deacyloxylation of esters normally requires reduction under strongly basic conditions e.g.¹     

The Fundamental Convergence Theorem for <Emphasis Type="Italic">p</Emphasis>(·)-Superharmonic Functions

We study the balayage related to the supersolutions of the variable exponent p(·)-Laplace equation. We prove the fundamental convergence theorem for the balayage and apply it for proving the Kellogg property, boundary regularity results for the balayage, and a removability theorem for p(·)-solutions.