温度对潜望式激光通信终端SiC反射镜性能影响

分析了温度梯度和均匀温度对潜望式激光通信终端反射镜形变的影响,利用椭圆域上的Zerni-ke多项式对椭圆反射镜的波前进行拟合,计算由于热形变导致的波前畸变误差,给出了星间激光通信终端反射镜均方根值、发射光束瞄准误差、接收端光强随温度梯度和均匀温度的变化关系。结果表明:温度梯度对反射镜的影响只是引起峰值光强的漂移和少许下降,当温度梯度为14℃/m时瞄准误差达2.1μrad。均匀温度会引起接收端的光强分布变化,从而导致很大的瞄准误差和光强衰减,当均匀温度与参考温度的差值小于0.6℃时,由波前畸变误差引起的瞄准误差小于1μrad,当差值大于0.6℃时,瞄准误差突然增大到几μrad,接收端光强分布发生变化,此时反射镜热形变引起的像散项对光强分布起重要作用。     

激磁电感对直线变压器输出波形顶降的影响

 从理论上分析了激磁电感对直线变压器驱动源输出脉冲波形顶降的影响,使用Pspice软件对理论计算结果进行了模拟验证。理论计算和模拟分析的结果均表明：激磁电感越小,输出脉冲波形的顶降越明显。设计了50 A的偏磁电路并进行了实验,在重复频率为20 Hz时直线变压器驱动源工作稳定,输出脉冲波形前沿约35 ns,平顶约130 ns,幅值约125 kV。与未加偏磁电路的实验结果相比,顶降明显减小（小于5%）,实验结果与理论计算和模拟分析结果基本一致。     

化学发光法测定甲萘威

在NaOH介质中,铁氰化钾氧化鲁米诺产生化学发光,甲萘威对该发光反应有较强的抑制作用且抑制发光强度与甲萘威的浓度呈较好的线性关系,基于此性质建立了测定甲萘威的新方法。在实验的优化条件下,测定甲萘威的检出限为5.5×10-11mol.L-1,线性范围为1.5×10-10—4.0×10-8mol.L-1,对5.0×10-9mol.L-1甲萘威进行了11次平行测定,其RSD为1.74%。该法用于合成样品中甲萘威的测定,结果令人满意。     

Synthesis and Luminescent Properties of Lanthanide Complexes with Structurally Related Novel Multipodal Ligands

To explore the relationship between the structure of the ligands and the luminescent properties of the lanthanide complexes, a series of lanthanide nitrate complexes with two novel structurally related multipodal ligands, 1,3-bis{[(2’-(2-picolylaminoformyl))phenoxyl]methyl}benzene (L ^I ) and 1,2-bis{[(2’-(2-picolylaminoformyl))phenoxyl]methyl}benzene (L ^II ), have been synthesized and characterized by elemental analysis, infrared spectra and molar conductivity measurements. At the same time, the luminescent properties of the Eu(III) and Tb(III) nitrate complexes in solid state and the Tb(III) nitrate complexes in solvents were investigated at room temperature. Under the excitation of UV light, these complexes exhibited characteristic emissions of central metal ions. The lowest triplet state energy levels T₁ of these ligands both match better to the lowest resonance energy level of Tb(III) than to Eu(III) ion. The influence of the structure of the ligands on the luminescent intensity of the complexes was also discussed.     

The high squeezing and entanglement in regular loss modulated optical parametric amplifier

We investigate the quantum fluctuation characteristic for time dependent regular loss modulated optical parametric amplifier for below and above threshold regions.It is found that a high squeezing and entanglement can be achieved.     

Effect of polarization on efficiency of volume Bragg grating filter

<正>Diffraction efficiency of volume Bragg grating,whose period is in the same order as the incident wavelength, is related to the polarization direction of the incident linear polarized beam.When two linearly polarized recording beams with the same polarization direction are used for recording volume Bragg gratings in a photopolymer with diffusion amplification,the azimuth of polarization of the reconstruction beam influences the diffraction efficiency of the grating.When the probe beam is linearly polarized and oriented orthogonally to the grating vectors,the±1-order diffraction beams are also linearly polarized with polarization direction parallel to that of the probe beam.According to the results,a two-dimensional nonspatial optical filter consisting of the volume Bragg gratings would achieve significantly higher efficiency.     

Tagged molecule induced nanoparticle aggregation： Raman reporter-labeled immuno-Au aggregate as immuno-sensor

<正>A novel structure with high surface enhanced Raman scattering(SERS) activity and bio-specificity as a SERS-based immuno-sensor(named as Raman reporter-labeled immuno-Au aggregate) is demonstrated and employed for protein detection.In each fabrication process,the features of those aggregates are obtained and characterized by ultraviolet-visible(UV-Vis) extinction spectra,transmission electron microscopy (TEM) images,scanning electron microscopy(SEM) pictures,and SERS spectra.Experimental results indicate that proper amounts of the reporter molecules can result in the moderate aggregation morphologies of gold nanoparticles.Compared with the previously reported method using Raman reporterlabeled immuno-Au nanoparticles,more sensitive SERS-based protein detection is realized with this novel immuno-sensor.     

Circulation times of hepatocellular carcinoma cells by in vivo flow cytometry

Hepatocellular carcinoma （HCC） may metastasize to many organs. The survival rate is almost zero for metastatic HCC patients. Molecular mechanisms of HCC metastasis need to be understood better and new therapies must be developed. We have developed the ＂in vivo microscopy＂ to study the mechanisms that govern liver tumor cells spreading through the microenvironment in vivo. A recently developed ＂in vivo flow cytometer＂ combined with real-time confocal fluorescence imaging is used to assess spreading and the circulation kinetics of liver tumor cells. We measure the depletion kinetics of two related human HCC cell lines, high-metastatic HCCLM3 cells and low-metastatic HepG2 cells, which are from the same origin and obtained by repetitive screenings in mice. More than 60% of the HCCLM3 cells are depleted within the first hour. Interestingly, the low-metastatic HepG2 cells possess noticeably slower depletion kinetics. In comparison, less than 40% of the HepG2 cells are depleted within the first hour. The differences in depletion kinetics might provide insights into early metastasis processes.     

Air-breathing mode a long-pulse laser propulsion with TE CO2 laser

Air-breathing mode laser propulsion experiment with a long-pulse transversely excited （TE） CO2 laser is carried out, and its ignition problem is solved with the ignition needle of lightcraft. Owing to the ignition needle, an order of magnitude reduction in the ignition threshold is demonstrated. The result is compared with previous study. The momentum coupling coefficient is also measured in the experiment and its dependence upon laser pulse energy （6 14 J） and pulse width （20, 32, and 40 μs） is discussed.     

Utilization of 3'-carboxy-containing tyrosine derivatives as a new class of phosphotyrosyl mimetics in the preparation of novel non-phosphorylated cyclic peptide inhibitors of the Grb2-SH2 domain

A new class of phosphotyrosyl (pTyr) mimetics, distinct from the conventional pTyr mimetic design of adding non-hydrolyzable acidic functionalities to the 4'-position of phenylalanine, was created by introducing carboxy-containing groups to the 3'-position of tyrosine. The effect of the chain length of the carboxy substituent was examined. Reported herein is the chiral pool synthesis of the new pTyr mimetics, and their first use in a novel non-phosphorylated Grb2-SH2 domain binding motif with the 5-amino-acid sequence Xx1-Leu-(3'-substituted-Tyr)-Ac6c-Asn. The highest affinity was exhibited by the 3-L-(2-carboxyethyl)tyrosine-containing sulfoxide-cyclized peptide , with an IC50 = 1.1 microM, providing a promising new template for further development of potent Grb2-SH2 domain inhibitors with reduced charge and peptidic nature, but improved selectivity and bioavailability.