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71.
Sudhakar Chaudhary V.V.K. Srinivas Kumar 《Numerical Methods for Partial Differential Equations》2013,29(4):1322-1340
In this article, we give some numerical techniques and error estimates using web‐spline based mesh‐free finite element method for the heat equation and the time‐dependent Navier–Stokes equations on bounded domains. The web‐spline method uses weighted extended B‐splines on a regular grid as basis functions and does not require any grid generation. We demonstrate the method by providing numerical results for the Poisson's and stationary Stokes equation. © 2012 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2013 相似文献
72.
Collective syntheses of five spiro[4.5]decane framework bearing sesquiterpenoids, namely, α & β-vetispirenes, β-vetivone, agarospirol and hinesol as well as formal synthesis of axenol and gleenol from a readily available precursor cyclohexanone-β-ketoester via the intermediacy of a versatile intermediate (2,10-dimethylspiro[4.5]dec-1-en-6-one) have been accomplished in a concise manner. 相似文献
73.
Sreenu Kurra Perala Venkataswamy Gundeboina Ravi Chandhiri Sudhakar Reddy Boggu Jaganmohan Reddy Muga Vithal 《无机化学与普通化学杂志》2019,645(5):529-536
Perovskite type oxides, sodium bismuth titanate (Na0.5Bi0.5TiO3), and Ag+, Cu2+, and Sn2+ doped Na0.5Bi0.5TiO3 were prepared by pechini and ion exchange methods, respectively. Photocatalytic activities of these catalysts were tested by decomposition of methylene blue (MB) under visible light irradiation. Results showed that the photocatalytic activity of metal ion doped Na0.5Bi0.5TiO3 was higher than undoped Na0.5Bi0.5TiO3. Relatively high photocatalytic performance of Ag+‐doped Na0.5Bi0.5TiO3 is mainly ascribed to the efficient separation of electron‐hole (e–, h+) pairs, lower bandgap energy and the creation of active hydroxyl radicals ( ? OH). Further, the Ag+‐doped Na0.5Bi0.5TiO3 catalyst showed good reusability up to four cycles. A possible mechanism for the enhanced photocatalytic performance was proposed. The synthesized photocatalysts were characterized by XRD, SEM, EDS, XPS, FT‐IR, and UV/Vis DRS techniques. 相似文献
74.
Muhammad Tayyab Akhtar Muneeba Samar Anam Amin Shami Muhammad Waseem Mumtaz Hamid Mukhtar Amna Tahir Syed Shahzad-ul-Hussan Safee Ullah Chaudhary Ubedullah Kaka 《Molecules (Basel, Switzerland)》2021,26(15)
Meat is a rich source of energy that provides high-value animal protein, fats, vitamins, minerals and trace amounts of carbohydrates. Globally, different types of meats are consumed to fulfill nutritional requirements. However, the increasing burden on the livestock industry has triggered the mixing of high-price meat species with low-quality/-price meat. This work aimed to differentiate different meat samples on the basis of metabolites. The metabolic difference between various meat samples was investigated through Nuclear Magnetic Resonance spectroscopy coupled with multivariate data analysis approaches like principal component analysis (PCA) and orthogonal partial least square-discriminant analysis (OPLS-DA). In total, 37 metabolites were identified in the gluteal muscle tissues of cow, goat, donkey and chicken using 1H-NMR spectroscopy. PCA was found unable to completely differentiate between meat types, whereas OPLS-DA showed an apparent separation and successfully differentiated samples from all four types of meat. Lactate, creatine, choline, acetate, leucine, isoleucine, valine, formate, carnitine, glutamate, 3-hydroxybutyrate and α-mannose were found as the major discriminating metabolites between white (chicken) and red meat (chevon, beef and donkey). However, inosine, lactate, uracil, carnosine, format, pyruvate, carnitine, creatine and acetate were found responsible for differentiating chevon, beef and donkey meat. The relative quantification of differentiating metabolites was performed using one-way ANOVA and Tukey test. Our results showed that NMR-based metabolomics is a powerful tool for the identification of novel signatures (potential biomarkers) to characterize meats from different sources and could potentially be used for quality control purposes in order to differentiate different meat types. 相似文献
75.
Swati Chauhan Priyanka Chaudhary Adesh Kumar Singh Pratibha Verma Vandana Srivastava Jeyakumar Kandasamy 《Tetrahedron letters》2018,59(3):272-276
A simple and efficient method for the dimerization of primary thioamides into 1,2,4-thiadiazoles using tert-butyl nitrite is described. The optimized condition was also found to be suitable for the dimerization of benzoselenoamides into 1,2,4-selenadiazoles. All the reactions proceed smoothly at room temperature and gave the desired products in excellent yields in a short span of time. 相似文献
76.
Muhammad Umair Hanif Adnan Yaseen Roquyya Gul Muhammad Usman Mirza Muhammad Hassan Nawaz Syed Shoaib Ahmed Salman Aziz Saima Chaudhary Ayyaz Ali Khan Muhammad Shoaib 《Applied biochemistry and biotechnology》2018,186(1):256-270
Small ubiquitin-like modifier (SUMO) fusion technology is widely used in the production of heterologous proteins from prokaryotic system to aid in protein solubilization and refolding. Due to an extensive clinical application of human bone morphogenetic protein 2 (hBMP2) in bone augmentation, total RNA was isolated from human gingival tissue and mature gene was amplified through RT-PCR, cloned (pET21a), sequence analyzed, and submitted to GenBank (Accession no. KF250425). To obtain soluble expression, SUMO3 was tagged at the N-terminus of hBMP2 gene (pET21a/SUMO3-hBMP2), transferred in BL21 codon+, and ~?40% soluble expression was obtained on induction with IPTG. The dimerized hBMP2 was confirmed with Western blot, native PAGE analysis, and purified by fast protein liquid chromatography with 0.5 M NaCl elution. The cleavage of SUMO3 tag from hBMP2 converted it to an insoluble form. Computational 3D structural analysis of the SUMO3-hBMP2 was performed and optimized by molecular dynamic simulation. Protein-protein interaction of SUMO3-hBMP2 with BMP2 receptor was carried out using HADDOCK and inferred stable interaction. The alkaline phosphatase assay of SUMO3-hBMP2 on C2C12 cells showed maximum 200-ng/ml dose-dependent activity. We conclude that SUMO3-tagged hBMP2 is more suited for generation of soluble form of the protein and addition of SUMO3 tag does not affect the functional activity of hBMP2. 相似文献
77.
Ramanjaneyulu GS Sudhakar N Rao BV Prabhakar S 《Rapid communications in mass spectrometry : RCM》2008,22(14):2241-2247
Febrifugine is an alkaloid with potent antimalarial activity isolated from Dichroa febrifuga and Hydrangea umbellate, and it exists naturally with its diastereomeric component, isofebrifugine. Here we report the differentiation of diastereomeric synthetic precursors of isofebrifugine (1, cis) and febrifugine (2, trans) and a structurally similar model diastereomeric pair without a halogen substituent (3 and 4) by electrospray ionization (ESI) tandem mass spectrometry. Compounds 1-4 contain a tert-butoxycarbonyl (BOC) substituent, and the collision-induced dissociation (CID) spectra of the [M+H](+), [M+Na](+) and [M+Li](+) ions of 1-4 include the expected product ions corresponding to the loss of C(4)H(8) (isobutene) and of C(5)H(8)O(2) (BOC-H). Loss of C(5)H(8)O(2) is dominant in cis isomers (1 and 3) and/or loss of C(4)H(8) ions is dominant in trans isomers (2 and 4). The decomposition of [M+H](+) ions shows stereoselectivity in the formation of the [M+H-(BOC-H)-C(3)H(5)OBr](+) and [M+H-(BOC-H)-C(6)H(5)CH(2)OH](+) ions. The [M+Cat](+) ions (where Cat = Na or Li) additionally show loss of NaBr and HBr from [M+Cat-(BOC-H)](+), and these product ions are constantly more abundant in cis isomers than in trans isomers. The stereoselectivity for the product ion corresponding to the loss of [(BOC-H)+C(3)H(5)OBr] from [M+H](+) ions differs from that from [M+Cat](+) ions. 相似文献
78.
Sreenu K. Sudhakar Reddy CH. Reddy J. R. Velchuri Radha Palla Suresh Vithal M. 《Research on Chemical Intermediates》2016,42(6):5765-5777
Research on Chemical Intermediates - Substitutional doping of framework heteroatoms in photocatalysis is one of the approaches for harvesting visible light. Tunnel structure potassium antimony... 相似文献
79.
Iqbal A Siddiqui HL Ashraf CM Bukhari MH Akram CM 《Chemical & pharmaceutical bulletin》2007,55(7):1070-1072
Thirteen new Schiff bases derived from p-nitrobenzaldehyde were synthesized by condensation with the appropriate amines. An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spectroscopic techniques. Cytotoxicity for the titled compounds was studied against Brine Shrimp, used as the test animal. 相似文献
80.
We investigate the influence of the first-order correction of entropy caused by thermal quantum fluctuations on the thermodynamics of a logarithmic corrected charged black hole in massive gravity. For this black hole, we explore the thermodynamic quantities, such as entropy, Helmholtz free energy, internal energy, enthalpy, Gibbs free energy and specific heat. We discuss the influence of the topology of the event horizon, dimensions and nonlinearity parameter on the local and global stability of the black hole. As a result, it is found that the holographic dual parameter vanishes. This means that the thermal corrections have no significant role to disturb the holographic duality of the logarithmic charged black hole in massive gravity, although the thermal corrections have a substantial impact on the thermodynamic quantities in the high-energy limit and the stability conditions of black holes. 相似文献