全文获取类型
收费全文 | 4014篇 |
免费 | 246篇 |
国内免费 | 19篇 |
专业分类
化学 | 3236篇 |
晶体学 | 30篇 |
力学 | 153篇 |
数学 | 242篇 |
物理学 | 618篇 |
出版年
2023年 | 19篇 |
2022年 | 68篇 |
2021年 | 77篇 |
2020年 | 70篇 |
2019年 | 77篇 |
2018年 | 53篇 |
2017年 | 48篇 |
2016年 | 141篇 |
2015年 | 121篇 |
2014年 | 171篇 |
2013年 | 241篇 |
2012年 | 355篇 |
2011年 | 344篇 |
2010年 | 247篇 |
2009年 | 195篇 |
2008年 | 306篇 |
2007年 | 268篇 |
2006年 | 250篇 |
2005年 | 221篇 |
2004年 | 190篇 |
2003年 | 142篇 |
2002年 | 156篇 |
2001年 | 77篇 |
2000年 | 57篇 |
1999年 | 47篇 |
1998年 | 26篇 |
1997年 | 32篇 |
1996年 | 42篇 |
1995年 | 22篇 |
1994年 | 24篇 |
1993年 | 20篇 |
1992年 | 12篇 |
1991年 | 13篇 |
1990年 | 12篇 |
1989年 | 9篇 |
1988年 | 11篇 |
1987年 | 11篇 |
1986年 | 4篇 |
1985年 | 11篇 |
1984年 | 4篇 |
1983年 | 8篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 7篇 |
1979年 | 8篇 |
1978年 | 7篇 |
1977年 | 9篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1974年 | 6篇 |
排序方式: 共有4279条查询结果,搜索用时 15 毫秒
121.
A new chemiluminescence (CL) method for the selective determination of As(III) and As(V) ions in aqueous solution has been studied using a FIA system. The method is based on the increased CL intensity with the addition of As(V) ion into a solution of lucigenin and hydrogen peroxide. The addition of As(III) ion into the solution did not change the CL intensity. Total concentration of As ions was determined after pre-oxidation of As(III) to As(V) with hydrogen peroxide in basic solution. The As(III) content was estimated by subtracting the content of As(V) ion from total As concentration. The effects of concentrations of KOH and H2O2, and flow rates of reagents on CL intensity have been investigated. The calibration curve for As(V) ion was linear over the range from 1.0×10-2 to 10 μg/g, the coefficient of correlation was 0.997 and the detection limit was 5.0×10-3 μg/g under the optimal experimental conditions. 相似文献
122.
The polyphenolic profiles and antioxidant effects of Agastache rugosa Kuntze (Banga) flower,leaf, stem and root
下载免费PDF全文
![点击此处可从《Biomedical chromatography : BMC》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Yun‐Hi Kim Won Sup Lee Soo Jung Lee Jong Sung Jin A. M. Abd El‐Aty Ho‐Chul Shin Jae‐Han Shim Sung Chul Shin 《Biomedical chromatography : BMC》2016,30(2):225-231
Agastache rugosa Kuntze (Korean mint) is used as a spice and in folk medicine in East Asia. The present study identified a total of 18 polyphenols from the flower, leaf, stem and roots of this plant using high‐performance liquid chromatography–tandem mass spectrometry. Fourteen of these compounds had not previously been identified in these plant tissues. Each polyphenol was validated in comparison with external calibration curves constructed using structurally related compounds, with determination coefficients >0.9993. The limits of detection and quantification were 0.092–0.650 and 0.307–2.167 mg/L, respectively. Recoveries of 61.92–116.44% were observed at two spiking levels, with 0.91–11% precision, expressed as relative standard deviation (except anthraquinone spiked at 10 mg/L). Hydroxycinnamic acid was the most abundant compound in the root, while the flowers showed the highest total flavonoid level. Antioxidant activities, determined in terms of reducing power, Fe2+ chelating activity and the radical scavenging activities using α,α‐diphenyl‐β‐picrylhydrazyl and 2‐2?‐azino‐bis‐3‐ethylbenzothiazoline‐6‐sulfonic acid, increased in a concentration‐dependent manner; the highest activity was identified in the stems, followed by leaves > flowers > roots. These findings indicate that A. rugosa is a good source of bioactive compounds and can be used as a functional food. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
123.
124.
125.
126.
127.
128.
129.
Kyeong‐Ryoon Lee Sung Heum Choi Jin‐Sook Song Hyewon Seo Yoon‐Jee Chae Hwang Eui Cho Jin Hee Ahn Sung‐Hoon Ahn Myung Ae Bae 《Biomedical chromatography : BMC》2013,27(7):846-852
In this study, we developed a method for the determination of PF‐04620110 (2‐{(1r,4r)‐4‐[4‐(4‐amino‐5‐oxo‐7,8‐dihydropyrimido[5,4‐f][1,4]oxazepin‐6(5H)‐yl)phenyl]cyclohexyl}acetic acid), a novel diacylglycerol acyltransferase 1 (DGAT‐1) inhibitor, in rat plasma and validated it using liquid chromatography–tandem mass spectrometry (LC‐MS/MS). Rat plasma samples were processed following a protein precipitation method by using acetonitrile and were then injected into an LC‐MS/MS system for quantification. PF‐04620110 and imipramine (internal standard) were separated using a Hypersil Gold C18 column, with a mixture of acetonitrile and 10 mm ammonium formate (90:10, v/v) as the mobile phase. The ion transitions monitored in positive‐ion mode [M + H]+ of multiple‐reaction monitoring were m/z 397.0 → 260.2 for PF‐04620110 and m/z 280.8 → 86.0 for imipramine. The detector response was specific and linear for PF‐04620110 at concentrations within the range 0.05–50 µg/mL and the signal‐to‐noise ratios for the samples were ≥10. The intra‐ and inter‐day precision and accuracy of the method matched the acceptance criteria for assay validation. PF‐04620110 was stable under various processing and/or handling conditions. PF‐04620110 concentrations in the rat plasma samples could be measured up to 24 h after intravenous or oral administration of PF‐04620110, suggesting that the assay is useful for pharmacokinetic studies in rats. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
130.
Siyuan Li Feng Jin Mayavan Viji Hyeju Jo Jaeuk Sim Hak Sung Kim Heesoon Lee Jae-Kyung Jung 《Tetrahedron letters》2017,58(14):1417-1420
An efficient and facile two-step strategy for the synthesis of (Z)-aurone from arylacetylenes and salicyladehydes, via silver(I) nitrate mediated cyclization/oxidation in the presence of potassium carbonate has been developed. The key feature of our method was delicate cascade reaction, to provide the corresponding (Z)-aurone in high yield and good regio- and stereo selectivity. 相似文献