Use of zwitterionic buffer additives to improve the separation of proteins in capillary zone electrophoresis

In CZE, the adsorption of the proteins on the capillary wall is a common problem. This paper describes the simple method of utilizing zwitterionic buffer additives to improve the separation of proteins in untreated fused silica capillaries at neutral pH. Three kinds of zwitterion are evaluated in the separation of acidic, neutral, and basic proteins, including their effect on protein efficiency, mobility, separation, and resolution; the difference between the effects of the different additives are also highlighted. The method has proved to be a possible means of reducing protein adsorption, especially for basic proteins.     

Synthesis and characterization of novel thermoresponsive‐co‐biodegradable hydrogels composed of N‐isopropylacrylamide,poly(L‐lactic acid), and dextran

A series of novel multifunctional hydrogels that combined the merits of both thermoresponsive and biodegradable polymeric materials were designed, synthesized, and characterized. The hydrogels were copolymeric networks composed of N‐isopropylacrylamide (NIPAAM) as a thermoresponsive component, poly(L‐lactic acid) (PLLA) as a hydrolytically degradable and hydrophobic component, and dextran as an enzymatically degradable and hydrophilic component. The chemical structures of the hydrogels were characterized by an attenuated total reflection–Fourier transform infrared spectroscopy (ATR–FTIR) technique. The hydrogels were thermoresponsive, showing a lower critical solution temperature (LCST) at approximately 32 °C, and their swelling properties strongly depended on temperature changes, the balance of the hydrophilic/hydrophobic components, and the degradation of the PLLA component. The degradation of the hydrogels caused by hydrolytic cleavage of ester bonds in the PLLA component was faster at 25 °C below the LCST than at 37 °C above the LCST, determined by the ATR–FTIR technique. Due to their multifunctional properties, the designed hydrogels show great potential for biomedical applications, including drug delivery and tissue engineering. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 5054–5066, 2004     

The best uniform convergence rate of linear empirical bayes estimators

In this paper the thought on the uniform convergence of an empirical Bayes estimator or linear empirical Bayes (l.e.B.) estimator is advanced. Under two different models the l.e.B. estimators of the parameter are constructed respectively. It is proved that the convergence rates and uniform convergence rates of these l.e.B. estimators are all one with respect to the corresponding prior families. It is shown that the uniform convergence rate one is the best, under mild assumptions imposed on the conditional density of the sample.     

One convenient synthesis route to boron nitride nanotube

We describe one convenient synthesis route to boron nitride (BN) nanotube by the reaction of boron powder, iron oxide, and ammonium chloride at 600 °C for 12 h. Characterized by XRD, FTIR, XPS, TEM and SAED, the composition and morphology of the products are confirmed. The possible reaction mechanism is also discussed.     

Fixed Point Theorems on Product Topological Spaces and Applications

A new collectively fixed point theorem for a family of set-valued mappings defined on product spaces of non-compact topological spaces without linear structure is proved and some special cases are also discussed. As applications, some non-empty intersection theorems of sets with convex sections and equilibrium existence theorem of abstract economies are obtained under much weaker assumptions. Our results includes a number of known results as many special cases.     

因素空间与概念内涵的表示

本文综合应用因素空间、信息系统和重于关系的方法,讨论了概念的内涵表示及其他有关问题。特别是,对在描述概念问题中不同于内涵和外延的第三种方法,即典型示范表示做了进一步的分析。     

关于Echelon空间无穷矩阵变换集的有界性

无穷矩阵变换是研究序列空间理论的重要工具.研究一个空间到另一个空间无穷矩阵变换的形式,是序列空间理论中的重要内容,并且已有众多工作.本文将进一步研究一般的Echelon空间到空间l^p(1≤p≤∞),c、c₀的无穷矩阵变换集的有界性.所得结果的特例正是Echelon空间到l^p(1≤p≤∞)c、c₀无穷矩阵变换的形式,同时概括了前人的许多结果.     

一类周期种群系统的适定性及最优控制

本文研究了一类非线性周期种群系统的适定性及最优控制问题 .利用压缩不动点原理讨论了该种群系统的周期解的存在唯一性 .并用变分法给出了最优控制所满足的必要条件 .     

POSITIVE SOLUTIONS OF NONLOCAL BOUNDARY VALUE PROBLEM FOR NONLINEAR RETARDED DIFFERENTIAL EQUATION

§1　IntroductionAt present,boundary value problems (BVPs) are widely investigated with variousmethods and techniques. BVPs with integral boundary conditions constitute a veryinteresting class of problems such as multipoint,three-point,four-point and nonlocalboundary value problems which are considered by many authors.And the existence ofpositive solutions for these problems becomes the subjectof many papers[1—6] .In a recentpaper[7] ,the authors have studied the existence of positive solut…