Synthesis of acridines from diphenylamine-2-carboxaldehydes prepared via the mcfadyen-stevens reaction

A general synthesis of acridines has been developed using diphenylamine-2-carboxaldehydes. Diphenylamine-2-carboxylic acids are converted to their p-toluenesulfonylhydrazides which are decomposed using a modified McFadyen-Stevens reaction to yield an aldehyde derivative which affords the acridine upon treatment with mineral acid.     

Smoothing the Moment Estimator of the Extreme Value Parameter

Let {X _n be a sequence of i.i.d. random variables whose common distribution F belongs to the domain of attraction of an extreme value law. A semi-parametric estimator of the extreme value parameter is the Dekkers, Einmahl and de Haan [8] moment estimator. Practical use of this estimator requires the problematic choice of a number k=k(n) of upper order statistics and there are few reliable guidelines for this choice. An averaging or smoothing technique is proposed for this estimator yielding a less volatile function of k which in practice aids estimation.     

Processes of <Emphasis Type="Italic">r</Emphasis><Superscript><Emphasis Type="Italic">t</Emphasis><Emphasis Type="Italic">h</Emphasis></Superscript> largest

For integers n ≥ r, we treat the rth largest of a sample of size n as an \(\mathbb {R}^{\infty }\)-valued stochastic process in r which we denote as M^(r). We show that the sequence regarded in this way satisfies the Markov property. We go on to study the asymptotic behavior of M^(r) as r → ∞, and, borrowing from classical extreme value theory, show that left-tail domain of attraction conditions on the underlying distribution of the sample guarantee weak limits for both the range of M^(r) and M^(r) itself, after norming and centering. In continuous time, an analogous process Y^(r) based on a two-dimensional Poisson process on \(\mathbb {R}_{+}\times \mathbb {R}\) is treated similarly, but we note that the continuous time problems have a distinctive additional feature: there are always infinitely many points below the rth highest point up to time t for any t >?0. This necessitates a different approach to the asymptotics in this case.