Pressure sensitive paint demonstrates relationship between ejector wall pressure and aerodynamic performance

 This paper provides an example of the application of Pressure Sensitive Paint (PSP) to complex internal suspersonic flows and demonstrates the relationship between ejector wall pressure and aerodynamic performance. Details of such jet mixer-ejector nozzles are relevant to jet noise reduction programs. Several ejector configurations with straight, convergent, and divergent side walls were used in our experiments. The side-wall that was painted with PSP was also instrumented with an array of 156 pressure taps connected to Electronically Scanned Pressure (ESP) modules, enabling simultaneous measurement of “true” reference pressures. The PSP results agreed very well with the “true” reference pressures and also provided a detailed map of the complicated pressure patterns that could not be detected using the pressure taps. Finally, we also demonstrated the direct relationship between ejector side-wall pressure distribution and ejector performance characteristics such as exit mean flow uniformity, pumping, and thrust augmentation. Received: 16 December 1997/Accepted: 21 August 1998     

Metal‐based antitumor,cytotoxic and antimicrobial activity: pharmacological evaluation of Knoevenagel condensate β‐diketone Schiff base thiosemicarbazone Cu(II) and Zn(II) complexes

Knoevenagel condensate Schiff base ligands [L = 3‐cinnamalideneacetylacetone‐thiosemicarbazone (CAT)/3‐cinnama‐ lideneacetylacetoneethylthiosemicarbazone (CAET)/3‐cinnamalideneacetylacetonephenylthiosemicarbazone (CAPT)] and their copper/zinc complexes were synthesized. They were characterized by analytical and spectral techniques. From these data it was found that the ligands adopt square‐planar geometry on metalation with Cu²⁺ and Zn²⁺. To evaluate the antitumor and cytotoxic activity of the synthesized complexes in mice and human cancer cell lines, the antitumor activity of the complexes was evaluated against an Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed using survival time and short‐term in vitro cytotoxic activity. Oral administration of complexes (100 mg/kg) increased the survival time. The cytotoxic activity of complexes was evaluated using human breast cancer (MDA‐MB‐231), colon cancer (HCT‐116) and nonsmall lung cancer (NCI‐H‐23) cell lines. Both the complexes possessed significant antitumor and cytotoxic activity on EAC and human cancer cell lines. The in vitro antimicrobial screening effect of the investigated compounds was also tested against the various organisms by well diffusion method. Copyright © 2009 John Wiley & Sons, Ltd.