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221.
Challinor VL Hayes PY Bernhardt PV Kitching W Lehmann RP De Voss JJ 《The Journal of organic chemistry》2011,76(17):7275-7280
The absolute stereochemistry of the steroidal saponins bethosides B and C was previously assigned as (22R,25R) on the basis of work that employed Horeau's method. Our studies of helosides A and B created doubt about both the original assignment and consequently our conclusion that relied upon it. The absolute configurations of bethosides B and C are revised to (22S,25R) following X-ray crystallographic analysis of their aglycone. Synthesis and full spectral characterization of both the 22R and 22S aglycones is reported to facilitate future stereochemical assignments in this series of saponins. 相似文献
222.
Diffusion rate of dye-labelled PAMAM dendrimers through free-standing silica colloidal crystals was studied as a function of the dendrimer generation and nanopore size to determine the transport selectivity. 相似文献
223.
Le Gac S Najjari B Motreff N Remaud-Le Saec P Faivre-Chauvet A Dimanche-Boitrel MT Morgenstern A Bruchertseifer F Lachkar M Boitrel B 《Chemical communications (Cambridge, England)》2011,47(30):8554-8556
For the first time, α-emitter radioisotope (213)Bi has been incorporated into porphyrin chelates, with rates matching with the short period of the radionuclide. An in situ transmetalation mechanism involving the daughter isotope (209)Pb is expected to boost the (213)Bi radiolabeling process. 相似文献
224.
Lalueza P Monzón M Arruebo M Santamaria J 《Chemical communications (Cambridge, England)》2011,47(2):680-682
We show that Ag-containing zeolites are highly effective against Staphylococcus aureus (SA) bacteria even at low Ag loadings and in the presence of high (10(9) CFU per mL) bacterial concentrations. At short contact times the bactericidal efficiency correlates strongly with Ag(+) release. At longer times data dispersion is higher, probably as a consequence of bacterial metabolism. 相似文献
225.
Rangel TB Assreuy AM Pires Ade F Carvalho AU Benevides RG Simões Rda C Silva HC Bezerra MJ Nascimento AS Nascimento KS Nagano CS Sampaio AH Delatorre P Rocha BA Fernandes PM Cavada BS 《Molecules (Basel, Switzerland)》2011,16(6):5087-5103
DwL, a lectin extracted from the seeds of Dioclea wilsonii, is a metalloprotein with strong agglutinating activity against rabbit and ABO erythrocytes, inhibited by glucose and mannose. DwL was purified by affinity chromatography on a Sephadex G-50 column and ion exchange chromatography on a HiTrap SP XL column. SDS-PAGE revealed three electrophoretic bands corresponding to the α (25,634 ± 2 Da), β (12,873 ± 2 Da) and γ (12,779 ± 2 Da) chains. Protein sequencing was done by Tandem Mass Spectrometry. The primary sequence featured 237 amino acids and was highly homologous to other reported Diocleinae lectins. A complete X-ray dataset was collected at 2.0 ? for X-Man-complexed DWL crystals produced by the vapor diffusion method. The crystals were orthorhombic and belonged to the space group I222, with the unit-cell parameters a = 59.6, b = 67.9 and c = 109.0 ?. DWL differed in potency from other ConA-like lectins and was found to induce neutrophil migration in rats, making it particularly useful in structural/functional studies of this class of proteins. 相似文献
226.
227.
Juarez MF Soria FA Patrito EM Paredes-Olivera P 《Physical chemistry chemical physics : PCCP》2011,13(48):21411-21422
The design of silicon/alkyl layer/metal junctions for the formation of optimal top metal contacts requires knowledge of the mechanistic and energetic aspects of the interactions of metal atoms with the modified surface. This involves (a) the interaction of the metal with the terminal groups of the organic layer, (b) the diffusion of metal atoms through the organic layer and (c) the reactions of metal atoms with the silicon surface atoms. The diffusion through the monolayer and the metal catalyzed breakage of Si-C bonds must be avoided to obtain high quality junctions. In this work, we performed a comprehensive density functional theory investigation to identify the reaction pathways of all these processes. In the absence of a reactive terminal group, gold atoms may penetrate through a compact alkyl monolayer on Si(111) with no energy barrier. However, the presence of thiol terminal groups introduces a high energy barrier which blocks the diffusion of metals into the monolayer. The diffusion barriers increase in the order Ag < Au < Cu and correlate with the stability of metal-thiolate complexes whereas the barriers for the formation of metal silicides increase in the order Cu < Au < Ag in correlation with the increasing metallic radii. The reactivity of gold clusters with functionalized Si(111) surfaces was also investigated. Metal silicide formation can only be avoided by a compact monolayer terminated by a reactive functional group. The mechanistic and energetic picture obtained in this work contributes to understanding of the factors that influence the quality of top metal contacts during the formation of silicon/organic layer/metal junctions. 相似文献
228.
Saraví Cisneros H Erben MF Della Védova CO Laurella S Allegretti PE Furlong JJ 《European journal of mass spectrometry (Chichester, England)》2011,17(2):125-143
Tautomerism of some nitriles has been studied by mass spectrometry. The analysis of the corresponding mass spectra has allowed to assign some fragmentations to specific tautomers and to determine heats of tautomerization through temperature effects and electron energy studies. Experimental determinations are supported by theoretical calculations. The joint analysis of mass spectrometry and DFT-B3LYP data indicate that this tautomeric equilibrium can be studied by the experimental spectrometric strategy employed. 相似文献
229.
Cortez-Espinosa N Aviña-Verduzco JA Ramírez-Chávez E Molina-Torres J Ríos-Chávez P 《Natural product communications》2011,6(6):857-861
Acmella radicans (Asteraceae) produces at least seven alkamides, most with either an isobutyl- or phenylethyl group as the amine moiety. These moieties suggest that the amino acids valine and phenylalanine are the biosynthetic precursors of these alkamides. On the basis of labeled feeding experiments using either L-[2H8]valine or L-[2H8]phenylalanine we present evidence for the involvement of these two amino acids in the biosynthesis of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (affinin) (1), (2Z,4E)-N-(2-phenylethyl)-2,4-octadienamide (2), (2E)-N-(2-phenylethyl)-nona-2-en-6,8-diynamide (3), and 3-phenyl-N-(2-phenylethyl)-2-propenamide (4). Alkamides were isolated from young A. radicans plants and analyzed by gas chromatography-mass spectrometry (GC-MS). Additionally, in cell free in vitro experiments based on isobutyl and phenylethylamide biosynthesis, using a colorimetric assay and GC-MS, valine and phenylalanine decarboxylase activities were assayed in the soluble extract of A. radicans leaves. 相似文献
230.
Luis Alberto Rodríguez‐Picn Anna Patricia Rodríguez‐Picn Alejandro Alvarado‐Iniesta 《商业与工业应用随机模型》2019,35(3):504-521
Most modern products that are highly reliable are complex in their inner and outer structures. This situation indicates quality characterization by the interaction of multiple performance characteristics, which motivates the utilization of robust reliability models to obtain robust estimates. It is paramount to obtaining substantial information about a product's life cycle; therefore, when multiple performance characteristics are dependent, it is important to find models that address the joint distribution of performance degradation of such. In this paper, a reliability model for products with 2 fatigue‐crack growth characteristics related to 2 degradation processes is developed. The proposed model considers the dependence among degradation processes by using copula functions considering the marginal degradation processes as inverse Gaussian processes. The statistical inference is performed by using a Bayesian approach to estimate the parameters of the joint bivariate model. A time‐scale transformation is considered to assure monotone paths of the degradation trajectories. The comparison results of the reliability analysis, under both dependent and independent assumptions, are reported with the implementation of the proposed modeling in a case study, which consists of the crack propagation data of 2 terminals of an electronic device. 相似文献