A semi-Markov model of disease recurrence in insured dogs

We use a semi-Markov model to analyse the stochastic dynamics of disease occurrence of dogs insured in Canada from 1990 to 1999, and the probability pattern of death from illness. After statistically justifying the use of a stochastic model, we demonstrate that a stationary first-order semi-Markov process is appropriate for analysing the available data set. The probability transition function is estimated and its stationarity is tested statistically. Homogeneity of the semi-Markov model with respect to important covariates (such as geographic location, insurance plan, breed and age) is also statistically examined. We conclude with discussions and implications of our results in veterinary contents. Copyright © 2007 John Wiley & Sons, Ltd.     

Reactions of elemental phoshorus and phosphine with electrophiles in superbasic systems: XIX. Formation of the C-P bond with participation of elemental phosphorus under microwave assistance

Microwave irradiation facilitates phosphorylation of aryl methyl chlorides and styrene with red phosphorus in the presence of strong bases and increases the yield of the main products, tertiary phosphine oxides.     

Low-frequency static characterization of microstructures using acousto-optic modulated stroboscopic interferometer

Micro-electro-mechanical-systems (MEMS) structures such as microcantilevers, micromirrors, accelerometers, gyroscopes, and filters are some of the new types of integrated electro-mechanical microstructures in need of testing tools to measure precisely their static and dynamic properties. The acousto-optic-modulated-stroboscopic-interferometer (AOMSI) is an innovative tool that can be employed to investigate the above-mentioned characteristics for a given environmental condition. In this work, an optical non-contact system employing an acousto-optic-modulator (AOM) to conduct low frequency static characterization of MEMS microstructures is presented. The method is applied to a silicon-on-insulator (SOI) cantilever for demonstration purposes. The theoretical analysis is based on an energy approach. Experimental results are presented and compared with the theory, and are found to be in good agreement.     

Banach 空间二阶积-微分方程组初值问题

该文利用新的比较结果研究Banach 空间二阶积-微分方程组初值问题解的存在性.即使在有限维空间, 其结果也是新的.     

采用优化的DFTB参数对铜(111)表面碳二聚化的分子动力学研究

针对铜表面化学反应,我们发展了一套铜-碳体系的密度泛函紧束缚(DFTB)参数。测试结果表明这套参数可以很好的描述吸附铜或碳原子前后铜表面的几何结构和能量。基于这套参数,我们对Cu(111)表面的碳二聚化过程进行了分子模拟研究。即使在高温下,直接的分子动力学模拟也很难观察到碳二聚体的形成。这是因为高温下铜表面显著的结构弛豫一定程度上阻止了二聚化。为了研究高温下铜表面碳二聚化的机理,我们进行了赝动力学模拟。发现在二聚化的过程中,碳原子形成C-Cu-C桥状结构以后,会绕中间Cu原子转动,最后形成碳二聚体。1300 K下碳二聚化的自由能垒约0.9 eV。     

Robust tracking and model following based on discrete-time neuro-sliding mode control for uncertain time-delay systems

This paper proposes a discrete-time neuro-sliding mode control (NSMC) scheme to realize the problem of robust tracking and model following for a class of uncertain time-delay systems. It is shown that the proposed scheme guarantees the stability of closed-loop system and achieves zero-tracking error in the presence of state delays, input delays, parameter uncertainties, and external disturbances. The selection of sliding surface and the existence of sliding mode are two important issues, which have been addressed. This scheme not only assures robustness against time-delays, system uncertainties and disturbances, but also avoids chattering phenomenon and reaching phase. Moreover, the knowledge of upper bound of uncertainties is not required. Both the theoretical analysis and illustrative example demonstrate the validity of the proposed scheme.     

Elastic–plastic behavior of non-woven fibrous mats

Electrospinning is a novel method for creating non-woven polymer mats that have high surface area and high porosity. These attributes make them ideal candidates for multifunctional composites. Understanding the mechanical properties as a function of fiber properties and mat microstructure can aid in designing these composites. Further, a constitutive model which captures the membrane stress–strain behavior as a function of fiber properties and the geometry of the fibrous network would be a powerful design tool. Here, mats electrospun from amorphous polyamide are used as a model system. The elastic–plastic behavior of single fibers are obtained in tensile tests. Uniaxial monotonic and cyclic tensile tests are conducted on non-woven mats. The mat exhibits elastic–plastic stress–strain behavior. The transverse strain behavior provides important complementary data, showing a negligible initial Poisson's ratio followed by a transverse:axial strain ratio greater than ?1:1 after an axial strain of 0.02. A triangulated framework has been developed to emulate the fibrous network structure of the mat. The micromechanically based model incorporates the elastic–plastic behavior of single fibers into a macroscopic membrane model of the mat. This representative volume element based model is shown to capture the uniaxial elastic–plastic response of the mat under monotonic and cyclic loading. The initial modulus and yield stress of the mat are governed by the fiber properties, the network geometry, and the network density. The transverse strain behavior is linked to discrete deformation mechanisms of the fibrous mat structure including fiber alignment, fiber bending, and network consolidation. The model is further validated in comparison to experiments under different constrained axial loading conditions and found to capture the constraint effect on stiffness, yield, post-yield hardening, and post-yield transverse strain behavior. Due to the direct connection between microstructure and macroscopic behavior, this model should be extendable to other electrospun systems and other two dimensional random fibrous networks.     

Sodium ion ordering and vacancy cluster formation in NaxCoO2 (x=0.71 and 0.84) single crystals by synchrotron X-Ray diffraction

In the rich phase diagram of NaxCoO2, x=0.71 enjoys special stability and is called the Curie-Weiss metal due to its anomalous properties. Similarly, x=0.84 prepared from high temperature melt is a special end point beyond which the system phase separates. Using synchrotron x-ray diffraction on single crystals, we discovered sqrt[12]a and sqrt[13]a superlattice structures which we interpret as the ordering of Na (vacancy) clusters. These results lead to a picture of coexisting local moments and itinerant carriers and form the first step towards understanding the many anomalous properties of cobaltates.     

Reconfigurable Bioinspired Framework Nucleic Acid Nanoplatform Dynamically Manipulated in Living Cells for Subcellular Imaging

In nature, the formation of spider silk fibers begins with dimerizing the pH‐sensitive N‐terminal domains of silk proteins (spidroins) upon lowering pH, and provides a natural masterpiece for programmable assembly. Inspired by the similarity of pH‐dependent dimerization behaviors, introduced here is an i‐motif‐guided model to mimic the initial step of spidroin assembly at the subcellular level. A framework nucleic acid (FNA) nanoplatform is designed using two tetrahedral DNA nanostructures (TDNs) with different branched vertexes carrying a bimolecular i‐motif and a split ATP aptamer. Once TDNs enter acidic lysosomes within living cells, they assemble into a heterodimeric architecture, thereby enabling the formation of a larger‐size framework and meanwhile subcellular imaging in response to endogenous ATP, which can be dynamically manipulated by adjusting intracellular pH and ATP levels with external drug stimuli.